The apicomplexan parasite Toxoplasma gondii
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.21/14211 |
Resumo: | PTDC/CVT-CVT/31840/2017 |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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The apicomplexan parasite Toxoplasma gondiiToxoplasma gondiiToxoplasmosisParasiteTissue cystEndodyogenyLytic cycleLife cycleOocystApicomplexaEXPL/CVT-EPI/1945/2013PTDC/CVT-CVT/31840/2017PTDC/CVT-CVT/31840/2017EXPL/CVT-EPI/1945/2013Toxoplasma gondii is a ubiquitous zoonotic parasite with an obligatory intracellular lifestyle. It relies on a specialized set of cytoskeletal and secretory organelles for host cell invasion. When infecting its felid definitive host, T. gondii undergoes sexual reproduction in the intestinal epithelium, producing oocysts that are excreted with the feces and sporulate in the environment. In other hosts and/or tissues, T. gondii multiplies by asexual reproduction. Rapidly dividing tachyzoites expand through multiple tissues, particularly nervous and muscular tissues, and eventually convert to slowly dividing bradyzoites which produce tissue cysts, structures that evade the immune system and remain infective within the host. Infection normally occurs through ingestion of sporulated oocysts or tissue cysts. While T. gondii is able to infect virtually all warm-blooded animals, most infections in humans are asymptomatic, with clinical disease occurring most often in immunocompromised hosts or fetuses carried by seronegative mothers that are infected during pregnancy.MDPIRCIPLDelgado, Inês L. S.Zúquete, SaraSantos, DulceBasto, Afonso P.Leitão, AlexandreNolasco, Sofia2022-01-27T11:26:29Z2022-012022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/14211engDelgado IL, Zúquete S, Santos D, Basto AP, Leitão A, Nolasco S. The apicomplexan parasite Toxoplasma gondii. Encyclopedia. 2022;2(1):189-211.10.3390/encyclopedia2010012info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T10:10:04Zoai:repositorio.ipl.pt:10400.21/14211Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:22:03.764177Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The apicomplexan parasite Toxoplasma gondii |
title |
The apicomplexan parasite Toxoplasma gondii |
spellingShingle |
The apicomplexan parasite Toxoplasma gondii Delgado, Inês L. S. Toxoplasma gondii Toxoplasmosis Parasite Tissue cyst Endodyogeny Lytic cycle Life cycle Oocyst Apicomplexa EXPL/CVT-EPI/1945/2013 PTDC/CVT-CVT/31840/2017 |
title_short |
The apicomplexan parasite Toxoplasma gondii |
title_full |
The apicomplexan parasite Toxoplasma gondii |
title_fullStr |
The apicomplexan parasite Toxoplasma gondii |
title_full_unstemmed |
The apicomplexan parasite Toxoplasma gondii |
title_sort |
The apicomplexan parasite Toxoplasma gondii |
author |
Delgado, Inês L. S. |
author_facet |
Delgado, Inês L. S. Zúquete, Sara Santos, Dulce Basto, Afonso P. Leitão, Alexandre Nolasco, Sofia |
author_role |
author |
author2 |
Zúquete, Sara Santos, Dulce Basto, Afonso P. Leitão, Alexandre Nolasco, Sofia |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
RCIPL |
dc.contributor.author.fl_str_mv |
Delgado, Inês L. S. Zúquete, Sara Santos, Dulce Basto, Afonso P. Leitão, Alexandre Nolasco, Sofia |
dc.subject.por.fl_str_mv |
Toxoplasma gondii Toxoplasmosis Parasite Tissue cyst Endodyogeny Lytic cycle Life cycle Oocyst Apicomplexa EXPL/CVT-EPI/1945/2013 PTDC/CVT-CVT/31840/2017 |
topic |
Toxoplasma gondii Toxoplasmosis Parasite Tissue cyst Endodyogeny Lytic cycle Life cycle Oocyst Apicomplexa EXPL/CVT-EPI/1945/2013 PTDC/CVT-CVT/31840/2017 |
description |
PTDC/CVT-CVT/31840/2017 |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-27T11:26:29Z 2022-01 2022-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.21/14211 |
url |
http://hdl.handle.net/10400.21/14211 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Delgado IL, Zúquete S, Santos D, Basto AP, Leitão A, Nolasco S. The apicomplexan parasite Toxoplasma gondii. Encyclopedia. 2022;2(1):189-211. 10.3390/encyclopedia2010012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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