Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45
| Autor(a) principal: | |
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| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/135390 |
Resumo: | Funding: The Portuguese Mental Health Study was carried out by the Department of Mental Health, Faculty of Medical Sciences, NOVA University of Lisbon, with collaboration of the Portuguese Catholic University, and was funded by Champalimaud Foundation, Gulbenkian Foundation, Foundation for Science and Technology (FCT) and Ministry of Health |
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Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45A World Mental Health Surveys reportAnxiety disordersdepressioninternalizing disorderslatent class growth analysisApplied PsychologyPsychiatry and Mental healthSDG 3 - Good Health and Well-beingFunding: The Portuguese Mental Health Study was carried out by the Department of Mental Health, Faculty of Medical Sciences, NOVA University of Lisbon, with collaboration of the Portuguese Catholic University, and was funded by Champalimaud Foundation, Gulbenkian Foundation, Foundation for Science and Technology (FCT) and Ministry of HealthBackground Depressive and anxiety disorders are highly comorbid, which has been theorized to be due to an underlying internalizing vulnerability. We aimed to identify groups of participants with differing vulnerabilities by examining the course of internalizing psychopathology up to age 45. Methods We used data from 24158 participants (aged 45+) in 23 population-based cross-sectional World Mental Health Surveys. Internalizing disorders were assessed with the Composite International Diagnostic Interview (CIDI). We applied latent class growth analysis (LCGA) and investigated the characteristics of identified classes using logistic or linear regression. Results The best-fitting LCGA solution identified eight classes: A healthy class (81.9%), three childhood-onset classes with mild (3.7%), moderate (2.0%), or severe (1.1%) internalizing comorbidity, two puberty-onset classes with mild (4.0%) or moderate (1.4%) comorbidity, and two adult-onset classes with mild comorbidity (2.7% and 3.2%). The childhood-onset severe class had particularly unfavorable sociodemographic outcomes compared to the healthy class, with increased risks of being never or previously married (OR = 2.2 and 2.0, p < 0.001), not being employed (OR = 3.5, p < 0.001), and having a low/low-Average income (OR = 2.2, p < 0.001). Moderate or severe (v. mild) comorbidity was associated with 12-month internalizing disorders (OR = 1.9 and 4.8, p < 0.001), disability (B = 1.1-2.3, p < 0.001), and suicidal ideation (OR = 4.2, p < 0.001 for severe comorbidity only). Adult (v. childhood) onset was associated with lower rates of 12-month internalizing disorders (OR = 0.2, p < 0.001). Conclusions We identified eight transdiagnostic trajectories of internalizing psychopathology. Unfavorable outcomes were concentrated in the 1% of participants with childhood onset and severe comorbidity. Early identification of this group may offer opportunities for preventive interventions.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centro de Estudos de Doenças Crónicas (CEDOC)RUNDe Vries, Ymkje AnnaAl-Hamzawi, AliAlonso, JordiAndrade, Laura HelenaBenjet, CorinaBruffaerts, RonnyBunting, BrendanDe Girolamo, GiovanniFlorescu, SilviaGureje, OyeHaro, Josep MariaKaram, AimeeKaram, Elie G.Kawakami, NoritoKovess-Masfety, VivianeLee, SingMneimneh, ZeinaNavarro-Mateu, FernandoOjagbemi, AkinPosada-Villa, JoséScott, KateStagnaro, Juan CarlosTorres, YolandaXavier, MiguelZarkov, Zahari N.Kessler, Ronald C.De Jonge, Peter2022-03-29T01:36:15Z2022-08-102022-08-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/135390eng0033-2917PURE: 26488301https://doi.org/10.1017/S0033291720004031info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:13:44Zoai:run.unl.pt:10362/135390Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:48:23.076707Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45 A World Mental Health Surveys report |
| title |
Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45 |
| spellingShingle |
Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45 De Vries, Ymkje Anna Anxiety disorders depression internalizing disorders latent class growth analysis Applied Psychology Psychiatry and Mental health SDG 3 - Good Health and Well-being |
| title_short |
Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45 |
| title_full |
Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45 |
| title_fullStr |
Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45 |
| title_full_unstemmed |
Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45 |
| title_sort |
Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45 |
| author |
De Vries, Ymkje Anna |
| author_facet |
De Vries, Ymkje Anna Al-Hamzawi, Ali Alonso, Jordi Andrade, Laura Helena Benjet, Corina Bruffaerts, Ronny Bunting, Brendan De Girolamo, Giovanni Florescu, Silvia Gureje, Oye Haro, Josep Maria Karam, Aimee Karam, Elie G. Kawakami, Norito Kovess-Masfety, Viviane Lee, Sing Mneimneh, Zeina Navarro-Mateu, Fernando Ojagbemi, Akin Posada-Villa, José Scott, Kate Stagnaro, Juan Carlos Torres, Yolanda Xavier, Miguel Zarkov, Zahari N. Kessler, Ronald C. De Jonge, Peter |
| author_role |
author |
| author2 |
Al-Hamzawi, Ali Alonso, Jordi Andrade, Laura Helena Benjet, Corina Bruffaerts, Ronny Bunting, Brendan De Girolamo, Giovanni Florescu, Silvia Gureje, Oye Haro, Josep Maria Karam, Aimee Karam, Elie G. Kawakami, Norito Kovess-Masfety, Viviane Lee, Sing Mneimneh, Zeina Navarro-Mateu, Fernando Ojagbemi, Akin Posada-Villa, José Scott, Kate Stagnaro, Juan Carlos Torres, Yolanda Xavier, Miguel Zarkov, Zahari N. Kessler, Ronald C. De Jonge, Peter |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Centro de Estudos de Doenças Crónicas (CEDOC) RUN |
| dc.contributor.author.fl_str_mv |
De Vries, Ymkje Anna Al-Hamzawi, Ali Alonso, Jordi Andrade, Laura Helena Benjet, Corina Bruffaerts, Ronny Bunting, Brendan De Girolamo, Giovanni Florescu, Silvia Gureje, Oye Haro, Josep Maria Karam, Aimee Karam, Elie G. Kawakami, Norito Kovess-Masfety, Viviane Lee, Sing Mneimneh, Zeina Navarro-Mateu, Fernando Ojagbemi, Akin Posada-Villa, José Scott, Kate Stagnaro, Juan Carlos Torres, Yolanda Xavier, Miguel Zarkov, Zahari N. Kessler, Ronald C. De Jonge, Peter |
| dc.subject.por.fl_str_mv |
Anxiety disorders depression internalizing disorders latent class growth analysis Applied Psychology Psychiatry and Mental health SDG 3 - Good Health and Well-being |
| topic |
Anxiety disorders depression internalizing disorders latent class growth analysis Applied Psychology Psychiatry and Mental health SDG 3 - Good Health and Well-being |
| description |
Funding: The Portuguese Mental Health Study was carried out by the Department of Mental Health, Faculty of Medical Sciences, NOVA University of Lisbon, with collaboration of the Portuguese Catholic University, and was funded by Champalimaud Foundation, Gulbenkian Foundation, Foundation for Science and Technology (FCT) and Ministry of Health |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-03-29T01:36:15Z 2022-08-10 2022-08-10T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/135390 |
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http://hdl.handle.net/10362/135390 |
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eng |
| language |
eng |
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0033-2917 PURE: 26488301 https://doi.org/10.1017/S0033291720004031 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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