Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy

Detalhes bibliográficos
Autor(a) principal: Fraga, Maria
Data de Publicação: 2014
Outros Autores: Nunes da Silva, Maria João, Lucas, Margarida, Victorino, Rui M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/45855
Resumo: Copyright © Ordem dos Médicos 2014
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spelling Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsyNefrite tubulointersticial e uveíte com granulomas não caseosos na biópsia ósseaBone marrowGranulomaUveitisNephritis, interstitialCopyright © Ordem dos Médicos 2014The Tubulointerstitial Nephritis and Uveitis syndrome is a very rare condition, probably under-diagnosed in clinical practice. It is characterized by the combination of an interstitial nephritis and uveitis, and is an exclusion diagnosis. Tissue non caseating granuloma can be rarely present, with only 6 cases reported on bone marrow. We present a case of a 55 year old female with a 3-month history of asthenia and weight loss. Blood tests showed anemia and renal insufficiency. Renal biopsy revealed interstitial nephritis and the bone marrow biopsy showed caseating granuloma. One month later anterior uveitis of the left eye appeared. An extensive exclusion of all possible causes allowed a diagnosis of Tubulointerstitial Nephritis and Uveitis syndrome with caseating granuloma in bone marrow. As ocular and renal manifestations may not occur simultaneously, Tubulointerstitial Nephritis and Uveitis Syndrome should be systematically considered in cases of interstitial nephritis and/or uveitis, and tissue granulomas can be part of this rare syndrome.Ordem dos MédicosRepositório da Universidade de LisboaFraga, MariaNunes da Silva, Maria JoãoLucas, MargaridaVictorino, Rui M.2021-01-19T16:55:38Z20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/45855engActa Med Port 2014 Mar-Apr;27(2):268-2700870-399X10.20344/amp.39811646-0758info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:47:52Zoai:repositorio.ul.pt:10451/45855Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:58:12.298612Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy
Nefrite tubulointersticial e uveíte com granulomas não caseosos na biópsia óssea
title Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy
spellingShingle Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy
Fraga, Maria
Bone marrow
Granuloma
Uveitis
Nephritis, interstitial
title_short Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy
title_full Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy
title_fullStr Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy
title_full_unstemmed Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy
title_sort Tubulointerstitial nephritis and uveitis syndrome with non caseating granuloma in bone marrow biopsy
author Fraga, Maria
author_facet Fraga, Maria
Nunes da Silva, Maria João
Lucas, Margarida
Victorino, Rui M.
author_role author
author2 Nunes da Silva, Maria João
Lucas, Margarida
Victorino, Rui M.
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Fraga, Maria
Nunes da Silva, Maria João
Lucas, Margarida
Victorino, Rui M.
dc.subject.por.fl_str_mv Bone marrow
Granuloma
Uveitis
Nephritis, interstitial
topic Bone marrow
Granuloma
Uveitis
Nephritis, interstitial
description Copyright © Ordem dos Médicos 2014
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01T00:00:00Z
2021-01-19T16:55:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/45855
url http://hdl.handle.net/10451/45855
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Med Port 2014 Mar-Apr;27(2):268-270
0870-399X
10.20344/amp.3981
1646-0758
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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