The origin of island populations of the African malaria mosquito, Anopheles coluzzii

Detalhes bibliográficos
Autor(a) principal: Campos, Melina
Data de Publicação: 2021
Outros Autores: Hanemaaijer, Mark, Gripkey, Hans, Collier, Travis C., Lee, Yoosook, Cornel, Anthony J., Pinto, João, Ayala, Diego, Rompão, Herodes, Lanzaro, Gregory C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/122439
Resumo: Funding Information: This work was supported by grants from the UC Irvine Malaria Initiative Program, Open Philanthropy and NIH R56 grant (R56AI130277). We thank the National Malaria Control Program personnel from São Tomé and Príncipe and, Ministry of Health in São Tomé and Príncipe who facilitated our field collections in São Tomé. We thank the Centre International de Recherches Médicales de Franceville (Franceville, Gabon) for the collections in Gabon. Publisher Copyright: © 2021, The Author(s).
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spelling The origin of island populations of the African malaria mosquito, Anopheles coluzziiAnopheles coluzziimalariaIsland malariaAfricaAfricanGeneticsEcology, Evolution, Behavior and SystematicsInsect ScienceSDG 3 - Good Health and Well-beingSDG 15 - Life on LandFunding Information: This work was supported by grants from the UC Irvine Malaria Initiative Program, Open Philanthropy and NIH R56 grant (R56AI130277). We thank the National Malaria Control Program personnel from São Tomé and Príncipe and, Ministry of Health in São Tomé and Príncipe who facilitated our field collections in São Tomé. We thank the Centre International de Recherches Médicales de Franceville (Franceville, Gabon) for the collections in Gabon. Publisher Copyright: © 2021, The Author(s).Anopheles coluzzii is a major malaria vector throughout its distribution in west-central Africa. Here we present a whole-genome study of 142 specimens from nine countries in continental Africa and three islands in the Gulf of Guinea. This sample set covers a large part of this species’ geographic range. Our population genomic analyses included a description of the structure of mainland populations, island populations, and connectivity between them. Three genetic clusters are identified among mainland populations and genetic distances (FST) fits an isolation-by-distance model. Genomic analyses are applied to estimate the demographic history and ancestry for each island. Taken together with the unique biogeography and history of human occupation for each island, they present a coherent explanation underlying levels of genetic isolation between mainland and island populations. We discuss the relationship of our findings to the suitability of São Tomé and Príncipe islands as candidate sites for potential field trials of genetic-based malaria control strategies.Vector borne diseases and pathogens (VBD)Instituto de Higiene e Medicina Tropical (IHMT)Global Health and Tropical Medicine (GHTM)RUNCampos, MelinaHanemaaijer, MarkGripkey, HansCollier, Travis C.Lee, YoosookCornel, Anthony J.Pinto, JoãoAyala, DiegoRompão, HerodesLanzaro, Gregory C.2021-08-12T23:20:40Z2021-05-262021-05-26T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9application/pdfhttp://hdl.handle.net/10362/122439eng2399-3642PURE: 33050119https://doi.org/10.1038/s42003-021-02168-0info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:04:08Zoai:run.unl.pt:10362/122439Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:44:47.368961Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The origin of island populations of the African malaria mosquito, Anopheles coluzzii
title The origin of island populations of the African malaria mosquito, Anopheles coluzzii
spellingShingle The origin of island populations of the African malaria mosquito, Anopheles coluzzii
Campos, Melina
Anopheles coluzzii
malaria
Island malaria
Africa
African
Genetics
Ecology, Evolution, Behavior and Systematics
Insect Science
SDG 3 - Good Health and Well-being
SDG 15 - Life on Land
title_short The origin of island populations of the African malaria mosquito, Anopheles coluzzii
title_full The origin of island populations of the African malaria mosquito, Anopheles coluzzii
title_fullStr The origin of island populations of the African malaria mosquito, Anopheles coluzzii
title_full_unstemmed The origin of island populations of the African malaria mosquito, Anopheles coluzzii
title_sort The origin of island populations of the African malaria mosquito, Anopheles coluzzii
author Campos, Melina
author_facet Campos, Melina
Hanemaaijer, Mark
Gripkey, Hans
Collier, Travis C.
Lee, Yoosook
Cornel, Anthony J.
Pinto, João
Ayala, Diego
Rompão, Herodes
Lanzaro, Gregory C.
author_role author
author2 Hanemaaijer, Mark
Gripkey, Hans
Collier, Travis C.
Lee, Yoosook
Cornel, Anthony J.
Pinto, João
Ayala, Diego
Rompão, Herodes
Lanzaro, Gregory C.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Vector borne diseases and pathogens (VBD)
Instituto de Higiene e Medicina Tropical (IHMT)
Global Health and Tropical Medicine (GHTM)
RUN
dc.contributor.author.fl_str_mv Campos, Melina
Hanemaaijer, Mark
Gripkey, Hans
Collier, Travis C.
Lee, Yoosook
Cornel, Anthony J.
Pinto, João
Ayala, Diego
Rompão, Herodes
Lanzaro, Gregory C.
dc.subject.por.fl_str_mv Anopheles coluzzii
malaria
Island malaria
Africa
African
Genetics
Ecology, Evolution, Behavior and Systematics
Insect Science
SDG 3 - Good Health and Well-being
SDG 15 - Life on Land
topic Anopheles coluzzii
malaria
Island malaria
Africa
African
Genetics
Ecology, Evolution, Behavior and Systematics
Insect Science
SDG 3 - Good Health and Well-being
SDG 15 - Life on Land
description Funding Information: This work was supported by grants from the UC Irvine Malaria Initiative Program, Open Philanthropy and NIH R56 grant (R56AI130277). We thank the National Malaria Control Program personnel from São Tomé and Príncipe and, Ministry of Health in São Tomé and Príncipe who facilitated our field collections in São Tomé. We thank the Centre International de Recherches Médicales de Franceville (Franceville, Gabon) for the collections in Gabon. Publisher Copyright: © 2021, The Author(s).
publishDate 2021
dc.date.none.fl_str_mv 2021-08-12T23:20:40Z
2021-05-26
2021-05-26T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/122439
url http://hdl.handle.net/10362/122439
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2399-3642
PURE: 33050119
https://doi.org/10.1038/s42003-021-02168-0
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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