Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/80819 https://doi.org/10.1016/j.ijpharm.2013.02.049 |
Resumo: | Mutual diffusion coefficients, D, densities, ρ, and viscosities, η, are reported for aqueous solutions of L-3,4-dihydroxyphenylalanine (L-Dopa) at 298.15K and 310.15K at concentrations from (0.00025 to 0.0075) moldm(-3). The aim of this study is to contribute to a better understanding of the structure of these systems and the thermodynamic behaviour of L-Dopa in solution. Thus, from these experimental data it was possible to estimate some parameters, such as the hydrodynamic radius, Rh, apparent molar volumes, ϕV, and diffusion coefficients at infinitesimal concentration, D(0), essential for a better understanding of disperse systems. From the measured diffusion coefficients, activity coefficients, γ, for aqueous L-Dopa solutions were also estimated by using Nernst-Hartley equation. The effect of the viscosity on the estimated hydrodynamic radius was also studied. |
id |
RCAP_9eb87f774d6f308e7e9dc626d6d7bfde |
---|---|
oai_identifier_str |
oai:estudogeral.uc.pt:10316/80819 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutionsMutual diffusion coefficients, D, densities, ρ, and viscosities, η, are reported for aqueous solutions of L-3,4-dihydroxyphenylalanine (L-Dopa) at 298.15K and 310.15K at concentrations from (0.00025 to 0.0075) moldm(-3). The aim of this study is to contribute to a better understanding of the structure of these systems and the thermodynamic behaviour of L-Dopa in solution. Thus, from these experimental data it was possible to estimate some parameters, such as the hydrodynamic radius, Rh, apparent molar volumes, ϕV, and diffusion coefficients at infinitesimal concentration, D(0), essential for a better understanding of disperse systems. From the measured diffusion coefficients, activity coefficients, γ, for aqueous L-Dopa solutions were also estimated by using Nernst-Hartley equation. The effect of the viscosity on the estimated hydrodynamic radius was also studied.2013-04-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/80819http://hdl.handle.net/10316/80819https://doi.org/10.1016/j.ijpharm.2013.02.049por1873-347623467077Barros, Marisa C. F.Ribeiro, Ana C. F.Valente, Artur J. M.Lobo, Victor M. M.Cabral, Ana M. T. D. P. V.Veiga, Francisco J. B.Teijeiro, CarmenEsteso, Miguel A.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2021-11-08T11:08:39Zoai:estudogeral.uc.pt:10316/80819Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:03:06.223593Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions |
title |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions |
spellingShingle |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions Barros, Marisa C. F. |
title_short |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions |
title_full |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions |
title_fullStr |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions |
title_full_unstemmed |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions |
title_sort |
Mass transport techniques as a tool for a better understanding of the structure of L-Dopa in aqueous solutions |
author |
Barros, Marisa C. F. |
author_facet |
Barros, Marisa C. F. Ribeiro, Ana C. F. Valente, Artur J. M. Lobo, Victor M. M. Cabral, Ana M. T. D. P. V. Veiga, Francisco J. B. Teijeiro, Carmen Esteso, Miguel A. |
author_role |
author |
author2 |
Ribeiro, Ana C. F. Valente, Artur J. M. Lobo, Victor M. M. Cabral, Ana M. T. D. P. V. Veiga, Francisco J. B. Teijeiro, Carmen Esteso, Miguel A. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Barros, Marisa C. F. Ribeiro, Ana C. F. Valente, Artur J. M. Lobo, Victor M. M. Cabral, Ana M. T. D. P. V. Veiga, Francisco J. B. Teijeiro, Carmen Esteso, Miguel A. |
description |
Mutual diffusion coefficients, D, densities, ρ, and viscosities, η, are reported for aqueous solutions of L-3,4-dihydroxyphenylalanine (L-Dopa) at 298.15K and 310.15K at concentrations from (0.00025 to 0.0075) moldm(-3). The aim of this study is to contribute to a better understanding of the structure of these systems and the thermodynamic behaviour of L-Dopa in solution. Thus, from these experimental data it was possible to estimate some parameters, such as the hydrodynamic radius, Rh, apparent molar volumes, ϕV, and diffusion coefficients at infinitesimal concentration, D(0), essential for a better understanding of disperse systems. From the measured diffusion coefficients, activity coefficients, γ, for aqueous L-Dopa solutions were also estimated by using Nernst-Hartley equation. The effect of the viscosity on the estimated hydrodynamic radius was also studied. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-04-15 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/80819 http://hdl.handle.net/10316/80819 https://doi.org/10.1016/j.ijpharm.2013.02.049 |
url |
http://hdl.handle.net/10316/80819 https://doi.org/10.1016/j.ijpharm.2013.02.049 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
1873-3476 23467077 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799133923582672896 |