Action Potential Monitoring Using Neuronanorobots: Neuroelectric Nanosensors

• Autor(a) principal: Martins, Nuno Ricardo Barbosa
• Data de Publicação: 2015
• Outros Autores: Erlhagen, Wolfram, Freitas, Robert
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/1822/51198
• topic: Human brain information; Nanorobotics; Neuronanorobotics

Neuronanorobotics, a key future medical technology that can enable the preservation of human brain information, requires appropriate nanosensors. Action potentials encode the most resource-intensive functional brain data. This paper presents a theoretical design for electrical nanosensors intended for use in neuronanorobots to provide non-destructive, in vivo, continuous, real-time, single-spike monitoring of action potentials initiated and processed within the ~86 × 109 neurons of the human brain as intermediated through the ~2.4 × 1014 human brain synapses. The proposed ~3375 nm3 FET-based neuroelectric nanosensors could detect action potentials with a temporal resolution of at least 0.1 ms, enough for waveform characterization even at the highest human neuron firing rates of 800 Hz.