Cholesterol-based compounds: Recent advances in synthesis and applications

Detalhes bibliográficos
Autor(a) principal: Albuquerque, Hélio
Data de Publicação: 2018
Outros Autores: Santos, Clementina M.M., Silva, Artur
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/8497
Resumo: This review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compounds
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spelling Cholesterol-based compounds: Recent advances in synthesis and applicationsBioactive compoundsBioimagingCholesterolDrug deliveryGelatorsLiquid crystalsSynthesisThis review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compoundsThanks are due to the University of Aveiro, Instituto Politécnico de Bragança, FCT/MEC for financial support of the QOPNA (FCT UID/QUI/00062/2013) and CIMO (UID/AGR/00690/2013) research units, through national funds, and where applicable cofinanced by the FEDER, within the PT2020 Partnership Agreement; and also to the Portuguese NMR Network. This work was also supported by the Integrated Programme of SR&TD “pAGE–Protein aggregation Across the Lifespan” (reference CENTRO-01-0145-FEDER-000003), co-funded by the Centro 2020 program, Portugal 2020, European Union, through the European Regional Development Fund. H. M. T. Albuquerque thanks the pAGE project for his Post-Doc grant (BPD/UI98/4861/2017).Biblioteca Digital do IPBAlbuquerque, HélioSantos, Clementina M.M.Silva, Artur2018-01-19T10:00:00Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/8497engAlbuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur (2019). Cholesterol-based compounds: Recent advances in synthesis and applications. Molecules. ISSN 1420-3049. 24:1, p. 1-6810.3390/molecules24010116info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:42:46Zoai:bibliotecadigital.ipb.pt:10198/8497Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:09:00.687369Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cholesterol-based compounds: Recent advances in synthesis and applications
title Cholesterol-based compounds: Recent advances in synthesis and applications
spellingShingle Cholesterol-based compounds: Recent advances in synthesis and applications
Albuquerque, Hélio
Bioactive compounds
Bioimaging
Cholesterol
Drug delivery
Gelators
Liquid crystals
Synthesis
title_short Cholesterol-based compounds: Recent advances in synthesis and applications
title_full Cholesterol-based compounds: Recent advances in synthesis and applications
title_fullStr Cholesterol-based compounds: Recent advances in synthesis and applications
title_full_unstemmed Cholesterol-based compounds: Recent advances in synthesis and applications
title_sort Cholesterol-based compounds: Recent advances in synthesis and applications
author Albuquerque, Hélio
author_facet Albuquerque, Hélio
Santos, Clementina M.M.
Silva, Artur
author_role author
author2 Santos, Clementina M.M.
Silva, Artur
author2_role author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Albuquerque, Hélio
Santos, Clementina M.M.
Silva, Artur
dc.subject.por.fl_str_mv Bioactive compounds
Bioimaging
Cholesterol
Drug delivery
Gelators
Liquid crystals
Synthesis
topic Bioactive compounds
Bioimaging
Cholesterol
Drug delivery
Gelators
Liquid crystals
Synthesis
description This review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compounds
publishDate 2018
dc.date.none.fl_str_mv 2018-01-19T10:00:00Z
2019
2019-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/8497
url http://hdl.handle.net/10198/8497
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Albuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur (2019). Cholesterol-based compounds: Recent advances in synthesis and applications. Molecules. ISSN 1420-3049. 24:1, p. 1-68
10.3390/molecules24010116
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
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instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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