Cholesterol-based compounds: Recent advances in synthesis and applications
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/8497 |
Resumo: | This review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compounds |
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Cholesterol-based compounds: Recent advances in synthesis and applicationsBioactive compoundsBioimagingCholesterolDrug deliveryGelatorsLiquid crystalsSynthesisThis review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compoundsThanks are due to the University of Aveiro, Instituto Politécnico de Bragança, FCT/MEC for financial support of the QOPNA (FCT UID/QUI/00062/2013) and CIMO (UID/AGR/00690/2013) research units, through national funds, and where applicable cofinanced by the FEDER, within the PT2020 Partnership Agreement; and also to the Portuguese NMR Network. This work was also supported by the Integrated Programme of SR&TD “pAGE–Protein aggregation Across the Lifespan” (reference CENTRO-01-0145-FEDER-000003), co-funded by the Centro 2020 program, Portugal 2020, European Union, through the European Regional Development Fund. H. M. T. Albuquerque thanks the pAGE project for his Post-Doc grant (BPD/UI98/4861/2017).Biblioteca Digital do IPBAlbuquerque, HélioSantos, Clementina M.M.Silva, Artur2018-01-19T10:00:00Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/8497engAlbuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur (2019). Cholesterol-based compounds: Recent advances in synthesis and applications. Molecules. ISSN 1420-3049. 24:1, p. 1-6810.3390/molecules24010116info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:42:46Zoai:bibliotecadigital.ipb.pt:10198/8497Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:09:00.687369Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Cholesterol-based compounds: Recent advances in synthesis and applications |
title |
Cholesterol-based compounds: Recent advances in synthesis and applications |
spellingShingle |
Cholesterol-based compounds: Recent advances in synthesis and applications Albuquerque, Hélio Bioactive compounds Bioimaging Cholesterol Drug delivery Gelators Liquid crystals Synthesis |
title_short |
Cholesterol-based compounds: Recent advances in synthesis and applications |
title_full |
Cholesterol-based compounds: Recent advances in synthesis and applications |
title_fullStr |
Cholesterol-based compounds: Recent advances in synthesis and applications |
title_full_unstemmed |
Cholesterol-based compounds: Recent advances in synthesis and applications |
title_sort |
Cholesterol-based compounds: Recent advances in synthesis and applications |
author |
Albuquerque, Hélio |
author_facet |
Albuquerque, Hélio Santos, Clementina M.M. Silva, Artur |
author_role |
author |
author2 |
Santos, Clementina M.M. Silva, Artur |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Albuquerque, Hélio Santos, Clementina M.M. Silva, Artur |
dc.subject.por.fl_str_mv |
Bioactive compounds Bioimaging Cholesterol Drug delivery Gelators Liquid crystals Synthesis |
topic |
Bioactive compounds Bioimaging Cholesterol Drug delivery Gelators Liquid crystals Synthesis |
description |
This review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compounds |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-19T10:00:00Z 2019 2019-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/8497 |
url |
http://hdl.handle.net/10198/8497 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Albuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur (2019). Cholesterol-based compounds: Recent advances in synthesis and applications. Molecules. ISSN 1420-3049. 24:1, p. 1-68 10.3390/molecules24010116 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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