Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/24365 |
Resumo: | Microencapsulation procedures have recently focused attention on designing novel mi-crospheres via green synthesis strategies. The use of chitosan (CS) as an encapsulating material has increased interest due to its unique bioactive properties and the various crosslinking possibilities offered by their functional groups. The consolidation of the microspheres by physical crosslinking using sodium tripolyphosphate (TPP) combined with chemical crosslinking using vanillin (VA) open new opportunities in the framework of green dual crosslinking strategies. The developed strategy, a straightforward technique based on an aqueous medium avoiding complex separa-tion/washing steps, offers advantages over the processes based on VA, mostly using water-in-oil emulsion approaches. Thus, in this work, the combination of TPP crosslinking (3, 5, and 10 wt.%) via spray-coagulation technique with two VA crosslinking methods (in situ and post-treatment using 1 wt.% VA) were employed in the preparation of microspheres. The microspheres were characterized concerning morphology, particle size, physicochemical properties, thermal stability, and swelling behavior. Results revealed that the combination of 5 wt.% TPP with in situ VA crosslinking led to microspheres with promising properties, being an attractive alternative for natural bioactives encapsulation due to the green connotations associated with the process. |
id |
RCAP_a0cab0202eb0ee106c2f190d02630782 |
---|---|
oai_identifier_str |
oai:bibliotecadigital.ipb.pt:10198/24365 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillinChitosan microspheresDual crosslinking strategiesGreen crosslinkerTripolyphos-phateVanillinMicroencapsulation procedures have recently focused attention on designing novel mi-crospheres via green synthesis strategies. The use of chitosan (CS) as an encapsulating material has increased interest due to its unique bioactive properties and the various crosslinking possibilities offered by their functional groups. The consolidation of the microspheres by physical crosslinking using sodium tripolyphosphate (TPP) combined with chemical crosslinking using vanillin (VA) open new opportunities in the framework of green dual crosslinking strategies. The developed strategy, a straightforward technique based on an aqueous medium avoiding complex separa-tion/washing steps, offers advantages over the processes based on VA, mostly using water-in-oil emulsion approaches. Thus, in this work, the combination of TPP crosslinking (3, 5, and 10 wt.%) via spray-coagulation technique with two VA crosslinking methods (in situ and post-treatment using 1 wt.% VA) were employed in the preparation of microspheres. The microspheres were characterized concerning morphology, particle size, physicochemical properties, thermal stability, and swelling behavior. Results revealed that the combination of 5 wt.% TPP with in situ VA crosslinking led to microspheres with promising properties, being an attractive alternative for natural bioactives encapsulation due to the green connotations associated with the process.Financial support by national funds FCT/MCTES to CIMO (UIDB/00690/2020). National funding by the FCT—Foundation for Science and Technology, through the institutional scientific employment program—contract with I.P.F. Further support was obtained through the Valor Natural project (Mobilized Project Norte-01-0247-FEDER-024479) and the GreenHealth project (Norte-01- 0145-FEDER-000042).Biblioteca Digital do IPBCorrea, Rodolpho FagundesColucci, GiovanaHalla, NoureddinePinto, João A.Santamaria-Echart, ArantzazuBlanco, Silvia PriscilaFernandes, Isabel P.Barreiro, M.F.2018-01-19T10:00:00Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/24365engCorrea, Rodolpho Fagundes; Colucci, Giovana; Halla, Noureddine; Pinto, João Alves; Santamaria-Echart, Arantzazu; Blanco, Silvia Priscila; Fernandes, Isabel Patrícia; Barreiro, Maria Filomena (2021). Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin. Molecules. ISSN 1420-3049. 26:8, p. 1-161420-304910.3390/molecules26082325info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:54:30Zoai:bibliotecadigital.ipb.pt:10198/24365Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:15:12.750132Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin |
title |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin |
spellingShingle |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin Correa, Rodolpho Fagundes Chitosan microspheres Dual crosslinking strategies Green crosslinker Tripolyphos-phate Vanillin |
title_short |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin |
title_full |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin |
title_fullStr |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin |
title_full_unstemmed |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin |
title_sort |
Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin |
author |
Correa, Rodolpho Fagundes |
author_facet |
Correa, Rodolpho Fagundes Colucci, Giovana Halla, Noureddine Pinto, João A. Santamaria-Echart, Arantzazu Blanco, Silvia Priscila Fernandes, Isabel P. Barreiro, M.F. |
author_role |
author |
author2 |
Colucci, Giovana Halla, Noureddine Pinto, João A. Santamaria-Echart, Arantzazu Blanco, Silvia Priscila Fernandes, Isabel P. Barreiro, M.F. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Correa, Rodolpho Fagundes Colucci, Giovana Halla, Noureddine Pinto, João A. Santamaria-Echart, Arantzazu Blanco, Silvia Priscila Fernandes, Isabel P. Barreiro, M.F. |
dc.subject.por.fl_str_mv |
Chitosan microspheres Dual crosslinking strategies Green crosslinker Tripolyphos-phate Vanillin |
topic |
Chitosan microspheres Dual crosslinking strategies Green crosslinker Tripolyphos-phate Vanillin |
description |
Microencapsulation procedures have recently focused attention on designing novel mi-crospheres via green synthesis strategies. The use of chitosan (CS) as an encapsulating material has increased interest due to its unique bioactive properties and the various crosslinking possibilities offered by their functional groups. The consolidation of the microspheres by physical crosslinking using sodium tripolyphosphate (TPP) combined with chemical crosslinking using vanillin (VA) open new opportunities in the framework of green dual crosslinking strategies. The developed strategy, a straightforward technique based on an aqueous medium avoiding complex separa-tion/washing steps, offers advantages over the processes based on VA, mostly using water-in-oil emulsion approaches. Thus, in this work, the combination of TPP crosslinking (3, 5, and 10 wt.%) via spray-coagulation technique with two VA crosslinking methods (in situ and post-treatment using 1 wt.% VA) were employed in the preparation of microspheres. The microspheres were characterized concerning morphology, particle size, physicochemical properties, thermal stability, and swelling behavior. Results revealed that the combination of 5 wt.% TPP with in situ VA crosslinking led to microspheres with promising properties, being an attractive alternative for natural bioactives encapsulation due to the green connotations associated with the process. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-19T10:00:00Z 2021 2021-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/24365 |
url |
http://hdl.handle.net/10198/24365 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Correa, Rodolpho Fagundes; Colucci, Giovana; Halla, Noureddine; Pinto, João Alves; Santamaria-Echart, Arantzazu; Blanco, Silvia Priscila; Fernandes, Isabel Patrícia; Barreiro, Maria Filomena (2021). Development of chitosan microspheres through a green dual crosslinking strategy based on tripolyphosphate and vanillin. Molecules. ISSN 1420-3049. 26:8, p. 1-16 1420-3049 10.3390/molecules26082325 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799135433975660544 |