Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies
Autor(a) principal: | |
---|---|
Data de Publicação: | 2023 |
Tipo de documento: | Dissertação |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.22/24664 |
Resumo: | Butylone (BTL) is a chiral synnthetic cathinone available as a racemate and reported in wastewaters. However, there are no studies on its impact on ecosystems and possible enantioselectivity. The objective of this woek was to evaluate: (i) the possible ecotoxicological effects on Daphnia magna of BTL in the form of racemate or its (R)- and (S)- enantiomers; and (ii) the efficiency of advanced oxidation tchnologies (AOT) in the removal and toxicity of BTL and its by-products in wastewaters. Enantiomers were sseparated by liquid chromatography using a chiral semi-preparative column, being obtained with high enantiomeric purity (˃97%). For toxicological studies, daphnia were exposed to concentrations of 0.1; 1 or 10 µg L-1 of the racemate or 0.1 or µg L-1 of each enatiomer. There were a significant morphophysiological, biochemical and repoductive changes depending on the formo f the substance and the development of the organism (juvenile or adult). Different AOTs (ozonation; O3; ultravioleta, UV; and UV/ O3) were apllied to wastewater spiked with BTL and acute toxicity tests (24 and 48h) demonstrated as a higher toxicity reduction of BTL-spiked effluents, with the highest reduction observed after UV and O3, respectively after 24 and 48h of exposure. |
id |
RCAP_a2a128b92ecddb02c95f65d75ecb449e |
---|---|
oai_identifier_str |
oai:recipp.ipp.pt:10400.22/24664 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologiesEmerging contaminantsPsychoactive substancesSynthetic cathinonesEcotoxicityAquatic organismsWastewatersButylone (BTL) is a chiral synnthetic cathinone available as a racemate and reported in wastewaters. However, there are no studies on its impact on ecosystems and possible enantioselectivity. The objective of this woek was to evaluate: (i) the possible ecotoxicological effects on Daphnia magna of BTL in the form of racemate or its (R)- and (S)- enantiomers; and (ii) the efficiency of advanced oxidation tchnologies (AOT) in the removal and toxicity of BTL and its by-products in wastewaters. Enantiomers were sseparated by liquid chromatography using a chiral semi-preparative column, being obtained with high enantiomeric purity (˃97%). For toxicological studies, daphnia were exposed to concentrations of 0.1; 1 or 10 µg L-1 of the racemate or 0.1 or µg L-1 of each enatiomer. There were a significant morphophysiological, biochemical and repoductive changes depending on the formo f the substance and the development of the organism (juvenile or adult). Different AOTs (ozonation; O3; ultravioleta, UV; and UV/ O3) were apllied to wastewater spiked with BTL and acute toxicity tests (24 and 48h) demonstrated as a higher toxicity reduction of BTL-spiked effluents, with the highest reduction observed after UV and O3, respectively after 24 and 48h of exposure.Ribeiro, ClaúdiaRibeiro, Ana Rita LadoAmorim, ManuelaRepositório Científico do Instituto Politécnico do PortoCarvalho, Ana Rita Teixeira2023-11-242024-11-24T00:00:00Z2023-11-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10400.22/24664TID:203469623enginfo:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-07T01:48:11Zoai:recipp.ipp.pt:10400.22/24664Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:59:03.555598Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies |
title |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies |
spellingShingle |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies Carvalho, Ana Rita Teixeira Emerging contaminants Psychoactive substances Synthetic cathinones Ecotoxicity Aquatic organisms Wastewaters |
title_short |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies |
title_full |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies |
title_fullStr |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies |
title_full_unstemmed |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies |
title_sort |
Toxicity of butylone and its enantiomers to Daphnia magna and its degradation by advanced oxidation technologies |
author |
Carvalho, Ana Rita Teixeira |
author_facet |
Carvalho, Ana Rita Teixeira |
author_role |
author |
dc.contributor.none.fl_str_mv |
Ribeiro, Claúdia Ribeiro, Ana Rita Lado Amorim, Manuela Repositório Científico do Instituto Politécnico do Porto |
dc.contributor.author.fl_str_mv |
Carvalho, Ana Rita Teixeira |
dc.subject.por.fl_str_mv |
Emerging contaminants Psychoactive substances Synthetic cathinones Ecotoxicity Aquatic organisms Wastewaters |
topic |
Emerging contaminants Psychoactive substances Synthetic cathinones Ecotoxicity Aquatic organisms Wastewaters |
description |
Butylone (BTL) is a chiral synnthetic cathinone available as a racemate and reported in wastewaters. However, there are no studies on its impact on ecosystems and possible enantioselectivity. The objective of this woek was to evaluate: (i) the possible ecotoxicological effects on Daphnia magna of BTL in the form of racemate or its (R)- and (S)- enantiomers; and (ii) the efficiency of advanced oxidation tchnologies (AOT) in the removal and toxicity of BTL and its by-products in wastewaters. Enantiomers were sseparated by liquid chromatography using a chiral semi-preparative column, being obtained with high enantiomeric purity (˃97%). For toxicological studies, daphnia were exposed to concentrations of 0.1; 1 or 10 µg L-1 of the racemate or 0.1 or µg L-1 of each enatiomer. There were a significant morphophysiological, biochemical and repoductive changes depending on the formo f the substance and the development of the organism (juvenile or adult). Different AOTs (ozonation; O3; ultravioleta, UV; and UV/ O3) were apllied to wastewater spiked with BTL and acute toxicity tests (24 and 48h) demonstrated as a higher toxicity reduction of BTL-spiked effluents, with the highest reduction observed after UV and O3, respectively after 24 and 48h of exposure. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-11-24 2023-11-24T00:00:00Z 2024-11-24T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/24664 TID:203469623 |
url |
http://hdl.handle.net/10400.22/24664 |
identifier_str_mv |
TID:203469623 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/embargoedAccess |
eu_rights_str_mv |
embargoedAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799137074758025216 |