Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health

Detalhes bibliográficos
Autor(a) principal: Melo, Xavier
Data de Publicação: 2017
Outros Autores: Santos, Diana A., Ornelas, Rui, Fernhall, Bo, Santa-Clara, Helena, Sardinha, Luís B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.13/3833
Resumo: Purpose: We examined whether exposure to high PP in adolescence predicts carotid artery intima-media thickness (IMT) and stiffness indices at young adulthood. Methods: Seventy-nine participants had their brachial systolic (SBP) and diastolic blood (DBP) pressures taken at the age of 15–16 years and later at young adulthood (29–31 years). Carotid IMT, distensibility and stiffness index b were measured at young adulthood. Linear and logistical regression analysis were performed. Results: PP at adolescence and at young adulthood predicted vascular health independently of sex, body mass index, and mean arterial pressure, explaining up to 37% of the variance. When analyzing its single constituents, at adolescence DBP was more predictive of vascular health, whereas DBP and SBP were equally important at young adulthood. Adolescents with high PP were at risk for increased carotid IMT (OR: 4.04–4.09), even if PP decreased at young adulthood. Young adults with high PP were at risk for increased stiffness regardless of adolescence PP (OR: 4.64–7.35). Conclusion: PP at adolescence and young adulthood may be a better predictor of early pathological changes in carotid artery structure and stiffness. Whereas carotid IMT in young adults appears to be influenced by PP at adolescence, carotid stiffness depends primarily on current PP.
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spelling Pulse pressure tracking from adolescence to young adulthood: contributions to vascular healthAtherosclerosisarteriosclerosisBlood pressureIntima media thicknessArterial stiffnessEpidemiology.Faculdade de Ciências SociaisPurpose: We examined whether exposure to high PP in adolescence predicts carotid artery intima-media thickness (IMT) and stiffness indices at young adulthood. Methods: Seventy-nine participants had their brachial systolic (SBP) and diastolic blood (DBP) pressures taken at the age of 15–16 years and later at young adulthood (29–31 years). Carotid IMT, distensibility and stiffness index b were measured at young adulthood. Linear and logistical regression analysis were performed. Results: PP at adolescence and at young adulthood predicted vascular health independently of sex, body mass index, and mean arterial pressure, explaining up to 37% of the variance. When analyzing its single constituents, at adolescence DBP was more predictive of vascular health, whereas DBP and SBP were equally important at young adulthood. Adolescents with high PP were at risk for increased carotid IMT (OR: 4.04–4.09), even if PP decreased at young adulthood. Young adults with high PP were at risk for increased stiffness regardless of adolescence PP (OR: 4.64–7.35). Conclusion: PP at adolescence and young adulthood may be a better predictor of early pathological changes in carotid artery structure and stiffness. Whereas carotid IMT in young adults appears to be influenced by PP at adolescence, carotid stiffness depends primarily on current PP.European Society of Hypertension (ESH)DigitUMaMelo, XavierSantos, Diana A.Ornelas, RuiFernhall, BoSanta-Clara, HelenaSardinha, Luís B.2021-11-18T14:28:12Z2017-01-01T00:00:00Z2017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.13/3833engMelo, X., Santos, D. A., Ornelas, R., Fernhall, B., Santa-Clara, H., & Sardinha, L. B. (2018). Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health. Blood pressure, 27(1), 19-24. https://doi.org/10.1080/08037051.2017.1360724 Melo, X., Santos, D. A., Ornelas, R., Fernhall, B., Santa-Clara, H., & Sardinha, L. B. (2018). Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health. Blood pressure, 27(1), 19-24. https://doi.org/10.1080/08037051.2017.1360710.1080/08037051.2017.1360724info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-05T12:56:54Zoai:digituma.uma.pt:10400.13/3833Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:07:18.510197Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health
title Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health
spellingShingle Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health
Melo, Xavier
Atherosclerosis
arteriosclerosis
Blood pressure
Intima media thickness
Arterial stiffness
Epidemiology
.
Faculdade de Ciências Sociais
title_short Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health
title_full Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health
title_fullStr Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health
title_full_unstemmed Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health
title_sort Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health
author Melo, Xavier
author_facet Melo, Xavier
Santos, Diana A.
Ornelas, Rui
Fernhall, Bo
Santa-Clara, Helena
Sardinha, Luís B.
author_role author
author2 Santos, Diana A.
Ornelas, Rui
Fernhall, Bo
Santa-Clara, Helena
Sardinha, Luís B.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv DigitUMa
dc.contributor.author.fl_str_mv Melo, Xavier
Santos, Diana A.
Ornelas, Rui
Fernhall, Bo
Santa-Clara, Helena
Sardinha, Luís B.
dc.subject.por.fl_str_mv Atherosclerosis
arteriosclerosis
Blood pressure
Intima media thickness
Arterial stiffness
Epidemiology
.
Faculdade de Ciências Sociais
topic Atherosclerosis
arteriosclerosis
Blood pressure
Intima media thickness
Arterial stiffness
Epidemiology
.
Faculdade de Ciências Sociais
description Purpose: We examined whether exposure to high PP in adolescence predicts carotid artery intima-media thickness (IMT) and stiffness indices at young adulthood. Methods: Seventy-nine participants had their brachial systolic (SBP) and diastolic blood (DBP) pressures taken at the age of 15–16 years and later at young adulthood (29–31 years). Carotid IMT, distensibility and stiffness index b were measured at young adulthood. Linear and logistical regression analysis were performed. Results: PP at adolescence and at young adulthood predicted vascular health independently of sex, body mass index, and mean arterial pressure, explaining up to 37% of the variance. When analyzing its single constituents, at adolescence DBP was more predictive of vascular health, whereas DBP and SBP were equally important at young adulthood. Adolescents with high PP were at risk for increased carotid IMT (OR: 4.04–4.09), even if PP decreased at young adulthood. Young adults with high PP were at risk for increased stiffness regardless of adolescence PP (OR: 4.64–7.35). Conclusion: PP at adolescence and young adulthood may be a better predictor of early pathological changes in carotid artery structure and stiffness. Whereas carotid IMT in young adults appears to be influenced by PP at adolescence, carotid stiffness depends primarily on current PP.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01T00:00:00Z
2017-01-01T00:00:00Z
2021-11-18T14:28:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.13/3833
url http://hdl.handle.net/10400.13/3833
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Melo, X., Santos, D. A., Ornelas, R., Fernhall, B., Santa-Clara, H., & Sardinha, L. B. (2018). Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health. Blood pressure, 27(1), 19-24. https://doi.org/10.1080/08037051.2017.1360724 Melo, X., Santos, D. A., Ornelas, R., Fernhall, B., Santa-Clara, H., & Sardinha, L. B. (2018). Pulse pressure tracking from adolescence to young adulthood: contributions to vascular health. Blood pressure, 27(1), 19-24. https://doi.org/10.1080/08037051.2017.13607
10.1080/08037051.2017.1360724
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv European Society of Hypertension (ESH)
publisher.none.fl_str_mv European Society of Hypertension (ESH)
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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