Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia
| Autor(a) principal: | |
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| Data de Publicação: | 2015 |
| Outros Autores: | , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | https://doi.org/10.1186/s13071-015-0976-1 |
Resumo: | WOS:000357470300003 PMID: 26152578 |
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oai:run.unl.pt:10362/36945 |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Exposure to Leishmania spp. and sand flies in domestic animals in northwestern EthiopiaDomestic animalsEthiopiaLeishmania donovaniPCRPhlebotomus orientalisSand fly salivaSerologyVisceral leishmaniasisParasitologyInfectious Diseasesveterinary(all)SDG 3 - Good Health and Well-beingWOS:000357470300003 PMID: 26152578Background: Human visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L. donovani foci, and the role of these animals as reservoirs for human L. donovani infection remains unclear. Methods: We conducted a study of domestic animals (goats, sheep, cows, dogs, and donkeys) in three L. donovani foci in northwestern Ethiopia. Domestic animals were screened for Leishmania DNA and for anti-L. donovani IgG. Serum anti-sand fly saliva antibodies were used as a marker of exposure to the vector sand fly, Phlebotomus orientalis. Results: Of 546 animals tested, 32 (5.9 %) were positive for Leishmania DNA, with positive animals identified among all species studied. Sequencing indicated that the animals were infected with parasites of the L. donovani complex but could not distinguish between L. infantum and L. donovani. A total of 18.9 % of the animals were seropositive for anti-L. donovani IgG, and 23.1 % of the animals were seropositive for anti-P. orientalis saliva IgG, with the highest seroprevalence observed in dogs and sheep. A positive correlation was found between anti-P. orientalis saliva and anti-L. donovani IgGs in cows, goats, and sheep. Conclusions: The detection of L. donovani complex DNA in the blood of domestic animals, the reported seroprevalence to the L. donovani antigen, and the widespread exposure to sand fly saliva among domestic animals indicate that they are frequently exposed to Leishmania infection and are likely to participate in the epidemiology of Leishmania infection, either as potential blood sources for sand flies or possibly as parasite hosts.Instituto de Higiene e Medicina Tropical (IHMT)Vector borne diseases and pathogens (VBD)Global Health and Tropical Medicine (GHTM)RUNRohousova, IvaTalmi-Frank, DalitKostalova, TatianaPolanska, NikolaLestinova, TerezaKassahun, AysheshmYasur-Landau, DanielMaia, CarlaKing, RoniVotypka, JanJaffe, Charles L.Warburg, AlonHailu, AsratVolf, PetrBaneth, Gad2018-05-14T22:02:24Z2015-07-082015-07-08T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.1186/s13071-015-0976-1engPURE: 1732124http://www.scopus.com/inward/record.url?scp=84935502580&partnerID=8YFLogxKhttps://doi.org/10.1186/s13071-015-0976-1info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:20:30Zoai:run.unl.pt:10362/36945Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:30:43.327041Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia |
| title |
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia |
| spellingShingle |
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia Rohousova, Iva Domestic animals Ethiopia Leishmania donovani PCR Phlebotomus orientalis Sand fly saliva Serology Visceral leishmaniasis Parasitology Infectious Diseases veterinary(all) SDG 3 - Good Health and Well-being |
| title_short |
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia |
| title_full |
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia |
| title_fullStr |
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia |
| title_full_unstemmed |
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia |
| title_sort |
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia |
| author |
Rohousova, Iva |
| author_facet |
Rohousova, Iva Talmi-Frank, Dalit Kostalova, Tatiana Polanska, Nikola Lestinova, Tereza Kassahun, Aysheshm Yasur-Landau, Daniel Maia, Carla King, Roni Votypka, Jan Jaffe, Charles L. Warburg, Alon Hailu, Asrat Volf, Petr Baneth, Gad |
| author_role |
author |
| author2 |
Talmi-Frank, Dalit Kostalova, Tatiana Polanska, Nikola Lestinova, Tereza Kassahun, Aysheshm Yasur-Landau, Daniel Maia, Carla King, Roni Votypka, Jan Jaffe, Charles L. Warburg, Alon Hailu, Asrat Volf, Petr Baneth, Gad |
| author2_role |
author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Instituto de Higiene e Medicina Tropical (IHMT) Vector borne diseases and pathogens (VBD) Global Health and Tropical Medicine (GHTM) RUN |
| dc.contributor.author.fl_str_mv |
Rohousova, Iva Talmi-Frank, Dalit Kostalova, Tatiana Polanska, Nikola Lestinova, Tereza Kassahun, Aysheshm Yasur-Landau, Daniel Maia, Carla King, Roni Votypka, Jan Jaffe, Charles L. Warburg, Alon Hailu, Asrat Volf, Petr Baneth, Gad |
| dc.subject.por.fl_str_mv |
Domestic animals Ethiopia Leishmania donovani PCR Phlebotomus orientalis Sand fly saliva Serology Visceral leishmaniasis Parasitology Infectious Diseases veterinary(all) SDG 3 - Good Health and Well-being |
| topic |
Domestic animals Ethiopia Leishmania donovani PCR Phlebotomus orientalis Sand fly saliva Serology Visceral leishmaniasis Parasitology Infectious Diseases veterinary(all) SDG 3 - Good Health and Well-being |
| description |
WOS:000357470300003 PMID: 26152578 |
| publishDate |
2015 |
| dc.date.none.fl_str_mv |
2015-07-08 2015-07-08T00:00:00Z 2018-05-14T22:02:24Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://doi.org/10.1186/s13071-015-0976-1 |
| url |
https://doi.org/10.1186/s13071-015-0976-1 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
PURE: 1732124 http://www.scopus.com/inward/record.url?scp=84935502580&partnerID=8YFLogxK https://doi.org/10.1186/s13071-015-0976-1 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
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application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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