Heart failure in Europe
| Autor(a) principal: | |
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| Data de Publicação: | 2024 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/172737 |
Resumo: | Funding Information: This work was supported by the following companies since the start of EORP and for the period of the ESC Heart Failure III study: Abbott Vascular Int. (2018\u20132021), Amgen Cardiovascular (2016\u20132018), AstraZeneca AB (2017\u20132020), Bayer AG (2016\u20132018), Boehringer Ingelheim (2016\u20132019), Bristol Myers Squibb (2017\u20132019), Daichii Sankyo Europe GmbH (2017\u20132020), Edwards Lifesciences (2016\u20132019), Novartis Pharma AG (2018\u20132020), Servier (2015\u20132021), and Vifor (2019\u20132021). Publisher Copyright: © 2024 European Society of Cardiology. |
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Heart failure in EuropeGuideline-directed medical therapy use and decision making in chronic and acute, pre-existing and de novo, heart failure with reduced, mildly reduced, and preserved ejection fraction – the ESC EORP Heart Failure III RegistryEjection fractionGuideline-directed medical therapyHeart failureImplementationQuality of careRegistryCardiology and Cardiovascular MedicineFunding Information: This work was supported by the following companies since the start of EORP and for the period of the ESC Heart Failure III study: Abbott Vascular Int. (2018\u20132021), Amgen Cardiovascular (2016\u20132018), AstraZeneca AB (2017\u20132020), Bayer AG (2016\u20132018), Boehringer Ingelheim (2016\u20132019), Bristol Myers Squibb (2017\u20132019), Daichii Sankyo Europe GmbH (2017\u20132020), Edwards Lifesciences (2016\u20132019), Novartis Pharma AG (2018\u20132020), Servier (2015\u20132021), and Vifor (2019\u20132021). Publisher Copyright: © 2024 European Society of Cardiology.Aims: We analysed baseline characteristics and guideline-directed medical therapy (GDMT) use and decisions in the European Society of Cardiology (ESC) Heart Failure (HF) III Registry. Methods and results: Between 1 November 2018 and 31 December 2020, 10 162 patients with acute HF (AHF, 39%, age 70 [62–79], 36% women) or outpatient visit for HF (61%, age 66 [58–75], 33% women), with HF with reduced (HFrEF, 57%), mildly reduced (HFmrEF, 17%) or preserved (HFpEF, 26%) ejection fraction were enrolled from 220 centres in 41 European or ESC-affiliated countries. With AHF, 97% were hospitalized, 2.2% received intravenous treatment in the emergency department, and 0.9% received intravenous treatment in an outpatient clinic. AHF was seen by most by a general cardiologist (51%) and outpatient HF most by a HF specialist (48%). A majority had been hospitalized for HF before, but 26% of AHF and 6.1% of outpatient HF had de novo HF. Baseline use, initiation and discontinuation of GDMT varied according to AHF versus outpatient HF, de novo versus pre-existing HF, and by ejection fraction. After the AHF event or outpatient HF visit, use of any renin–angiotensin system inhibitor, angiotensin receptor–neprilysin inhibitor, beta-blocker, mineralocorticoid receptor antagonist and loop diuretics was 89%, 29%, 92%, 78%, and 85% in HFrEF; 89%, 9.7%, 90%, 64%, and 81% in HFmrEF; and 77%, 3.1%, 80%, 48%, and 80% in HFpEF. Conclusion: Use and initiation of GDMT was high in cardiology centres in Europe, compared to previous reports from cohorts and registries including more primary care and general medicine and regions more local or outside of Europe and ESC-affiliated countries.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNLund, Lars H.Crespo-Leiro, Maria GenerosaLaroche, CécileZaliaduonyte, DianaSaad, Aly M.Fonseca, CandidaČelutkienė, JelenaZdravkovic, MarijaBielecka-Dabrowa, Agata M.Agostoni, PiergiuseppeXuereb, Robert G.Neronova, Kseniya V.Lelonek, MalgorzataCavusoglu, YukselGellen, BarnabasAbdelhamid, MagdyHammoudi, NaimaAnker, Stefan D.Chioncel, OvidiuFilippatos, GerasimosLainscak, MitjaMcDonagh, Theresa A.Mebazaa, AlexandrePiepoli, MassimoRuschitzka, F.Seferović, Petar M.Savarese, GianluigiMetra, MarcoRosano, Giuseppe M.C.Maggioni, Aldo P.Vahanian, A.Budaj, A.Dagres, N.Danchin, N.Delgado, V.Emberson, J.Friberg, O.Gale, C. P.Heyndrickx, G.Iung, B.James, S.Kappetein, A. P.Maggioni, A. P.Maniadakis, N.Tralhão, A.Brízido, C.Rocha, B.Presume, J.2024-09-30T22:31:34Z2024-09-102024-09-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/172737eng1388-9842PURE: 99817336https://doi.org/10.1002/ejhf.3445info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-10-07T01:39:19Zoai:run.unl.pt:10362/172737Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-10-07T01:39:19Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Heart failure in Europe Guideline-directed medical therapy use and decision making in chronic and acute, pre-existing and de novo, heart failure with reduced, mildly reduced, and preserved ejection fraction – the ESC EORP Heart Failure III Registry |
| title |
Heart failure in Europe |
| spellingShingle |
Heart failure in Europe Lund, Lars H. Ejection fraction Guideline-directed medical therapy Heart failure Implementation Quality of care Registry Cardiology and Cardiovascular Medicine |
| title_short |
Heart failure in Europe |
| title_full |
Heart failure in Europe |
| title_fullStr |
Heart failure in Europe |
| title_full_unstemmed |
Heart failure in Europe |
| title_sort |
Heart failure in Europe |
| author |
Lund, Lars H. |
| author_facet |
Lund, Lars H. Crespo-Leiro, Maria Generosa Laroche, Cécile Zaliaduonyte, Diana Saad, Aly M. Fonseca, Candida Čelutkienė, Jelena Zdravkovic, Marija Bielecka-Dabrowa, Agata M. Agostoni, Piergiuseppe Xuereb, Robert G. Neronova, Kseniya V. Lelonek, Malgorzata Cavusoglu, Yuksel Gellen, Barnabas Abdelhamid, Magdy Hammoudi, Naima Anker, Stefan D. Chioncel, Ovidiu Filippatos, Gerasimos Lainscak, Mitja McDonagh, Theresa A. Mebazaa, Alexandre Piepoli, Massimo Ruschitzka, F. Seferović, Petar M. Savarese, Gianluigi Metra, Marco Rosano, Giuseppe M.C. Maggioni, Aldo P. Vahanian, A. Budaj, A. Dagres, N. Danchin, N. Delgado, V. Emberson, J. Friberg, O. Gale, C. P. Heyndrickx, G. Iung, B. James, S. Kappetein, A. P. Maggioni, A. P. Maniadakis, N. Tralhão, A. Brízido, C. Rocha, B. Presume, J. |
| author_role |
author |
| author2 |
Crespo-Leiro, Maria Generosa Laroche, Cécile Zaliaduonyte, Diana Saad, Aly M. Fonseca, Candida Čelutkienė, Jelena Zdravkovic, Marija Bielecka-Dabrowa, Agata M. Agostoni, Piergiuseppe Xuereb, Robert G. Neronova, Kseniya V. Lelonek, Malgorzata Cavusoglu, Yuksel Gellen, Barnabas Abdelhamid, Magdy Hammoudi, Naima Anker, Stefan D. Chioncel, Ovidiu Filippatos, Gerasimos Lainscak, Mitja McDonagh, Theresa A. Mebazaa, Alexandre Piepoli, Massimo Ruschitzka, F. Seferović, Petar M. Savarese, Gianluigi Metra, Marco Rosano, Giuseppe M.C. Maggioni, Aldo P. Vahanian, A. Budaj, A. Dagres, N. Danchin, N. Delgado, V. Emberson, J. Friberg, O. Gale, C. P. Heyndrickx, G. Iung, B. James, S. Kappetein, A. P. Maggioni, A. P. Maniadakis, N. Tralhão, A. Brízido, C. Rocha, B. Presume, J. |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
| dc.contributor.author.fl_str_mv |
Lund, Lars H. Crespo-Leiro, Maria Generosa Laroche, Cécile Zaliaduonyte, Diana Saad, Aly M. Fonseca, Candida Čelutkienė, Jelena Zdravkovic, Marija Bielecka-Dabrowa, Agata M. Agostoni, Piergiuseppe Xuereb, Robert G. Neronova, Kseniya V. Lelonek, Malgorzata Cavusoglu, Yuksel Gellen, Barnabas Abdelhamid, Magdy Hammoudi, Naima Anker, Stefan D. Chioncel, Ovidiu Filippatos, Gerasimos Lainscak, Mitja McDonagh, Theresa A. Mebazaa, Alexandre Piepoli, Massimo Ruschitzka, F. Seferović, Petar M. Savarese, Gianluigi Metra, Marco Rosano, Giuseppe M.C. Maggioni, Aldo P. Vahanian, A. Budaj, A. Dagres, N. Danchin, N. Delgado, V. Emberson, J. Friberg, O. Gale, C. P. Heyndrickx, G. Iung, B. James, S. Kappetein, A. P. Maggioni, A. P. Maniadakis, N. Tralhão, A. Brízido, C. Rocha, B. Presume, J. |
| dc.subject.por.fl_str_mv |
Ejection fraction Guideline-directed medical therapy Heart failure Implementation Quality of care Registry Cardiology and Cardiovascular Medicine |
| topic |
Ejection fraction Guideline-directed medical therapy Heart failure Implementation Quality of care Registry Cardiology and Cardiovascular Medicine |
| description |
Funding Information: This work was supported by the following companies since the start of EORP and for the period of the ESC Heart Failure III study: Abbott Vascular Int. (2018\u20132021), Amgen Cardiovascular (2016\u20132018), AstraZeneca AB (2017\u20132020), Bayer AG (2016\u20132018), Boehringer Ingelheim (2016\u20132019), Bristol Myers Squibb (2017\u20132019), Daichii Sankyo Europe GmbH (2017\u20132020), Edwards Lifesciences (2016\u20132019), Novartis Pharma AG (2018\u20132020), Servier (2015\u20132021), and Vifor (2019\u20132021). Publisher Copyright: © 2024 European Society of Cardiology. |
| publishDate |
2024 |
| dc.date.none.fl_str_mv |
2024-09-30T22:31:34Z 2024-09-10 2024-09-10T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10362/172737 |
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http://hdl.handle.net/10362/172737 |
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eng |
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eng |
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1388-9842 PURE: 99817336 https://doi.org/10.1002/ejhf.3445 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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mluisa.alvim@gmail.com |
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