Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement

Detalhes bibliográficos
Autor(a) principal: Martins, T
Data de Publicação: 2016
Outros Autores: Valentim, AM, Pereira, N, Antunes, LM
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10216/116038
Resumo: Anaesthesia is used daily in fish experimental procedures; however, the use of an inadequate anaesthetic protocol can compromise not only the animal's welfare but also the reliability of results. The use of zebrafish (Danio rerio) in biomedical research has increased in the last decades, highlighting the importance of appropriate anaesthetic regimens for this species. This article reviews the main anaesthetic agents and protocols used in laboratory adult zebrafish, and some of the analgesic methods to be used in this species that still need more research. In addition, a systematized observation of signs is proposed to evaluate adult zebrafish welfare to reduce pain and distress.
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spelling Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinementAnalgesia/utilizationAnesthesia/utilizationAnesthetics/therapeutic useAnimal welfareAnimalsPain Measurement/methodsResearch DesignZebrafish/physiologyAnaesthesia is used daily in fish experimental procedures; however, the use of an inadequate anaesthetic protocol can compromise not only the animal's welfare but also the reliability of results. The use of zebrafish (Danio rerio) in biomedical research has increased in the last decades, highlighting the importance of appropriate anaesthetic regimens for this species. This article reviews the main anaesthetic agents and protocols used in laboratory adult zebrafish, and some of the analgesic methods to be used in this species that still need more research. In addition, a systematized observation of signs is proposed to evaluate adult zebrafish welfare to reduce pain and distress.Laboratory Animals20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10216/116038eng0023-677210.1177/0023677216670686Martins, TValentim, AMPereira, NAntunes, LMinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-09-27T06:47:37Zoai:repositorio-aberto.up.pt:10216/116038Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-09-27T06:47:37Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
title Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
spellingShingle Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
Martins, T
Analgesia/utilization
Anesthesia/utilization
Anesthetics/therapeutic use
Animal welfare
Animals
Pain Measurement/methods
Research Design
Zebrafish/physiology
title_short Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
title_full Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
title_fullStr Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
title_full_unstemmed Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
title_sort Anaesthesia and analgesia in laboratory adult zebrafish: a question of refinement
author Martins, T
author_facet Martins, T
Valentim, AM
Pereira, N
Antunes, LM
author_role author
author2 Valentim, AM
Pereira, N
Antunes, LM
author2_role author
author
author
dc.contributor.author.fl_str_mv Martins, T
Valentim, AM
Pereira, N
Antunes, LM
dc.subject.por.fl_str_mv Analgesia/utilization
Anesthesia/utilization
Anesthetics/therapeutic use
Animal welfare
Animals
Pain Measurement/methods
Research Design
Zebrafish/physiology
topic Analgesia/utilization
Anesthesia/utilization
Anesthetics/therapeutic use
Animal welfare
Animals
Pain Measurement/methods
Research Design
Zebrafish/physiology
description Anaesthesia is used daily in fish experimental procedures; however, the use of an inadequate anaesthetic protocol can compromise not only the animal's welfare but also the reliability of results. The use of zebrafish (Danio rerio) in biomedical research has increased in the last decades, highlighting the importance of appropriate anaesthetic regimens for this species. This article reviews the main anaesthetic agents and protocols used in laboratory adult zebrafish, and some of the analgesic methods to be used in this species that still need more research. In addition, a systematized observation of signs is proposed to evaluate adult zebrafish welfare to reduce pain and distress.
publishDate 2016
dc.date.none.fl_str_mv 2016
2016-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10216/116038
url http://hdl.handle.net/10216/116038
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0023-6772
10.1177/0023677216670686
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Laboratory Animals
publisher.none.fl_str_mv Laboratory Animals
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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