Utility of the PET/CT in the characterization of the solitary pulmonary nodule
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.25758/set.334 |
Resumo: | Background – Cancer of the lung/trachea and bronchi is the leading cause of death from cancer in the European Union. Dual time in Positron Emission Tomography/Computed Tomography (PET/CT) technique has been referred to in some articles as a great value in pulmonary cancer diagnosis. The aim of this study is to evaluate the PET/CT diagnostic accuracy with dual time in the characterization of the solitary pulmonary nodule (NSP), analyzing the nodule histology and size. Methodology – There were 115 NSPs analyzed, a total of 110 patients, where 65 were malignant. Two images were acquired, one with an average time of 52 minutes and another with 125 minutes after the 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) injection. To analyze those images it was obtained the standard uptake value (SUVmax) and percentage of changes in SUVmax (%variação) were. Results – The %variation shows higher values of diagnostic accuracy than when analyzing SUVmax separately. However there are significant differences in histology and SUVmax, registering also an increase of SUVmax2 in malignant pathologies comparatively with SUVmax1. Conclusion – Dual time technique showed to be more efficient in NSP characterization than when analyzing only one image. |
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Utility of the PET/CT in the characterization of the solitary pulmonary noduleUtilidade do PET/CT na caracterização do nódulo solitário pulmonarDuplo tempoNódulo solitário pulmonarSUVmax%variaçãoDual timeSolitary pulmonary noduleSUVmax%variationBackground – Cancer of the lung/trachea and bronchi is the leading cause of death from cancer in the European Union. Dual time in Positron Emission Tomography/Computed Tomography (PET/CT) technique has been referred to in some articles as a great value in pulmonary cancer diagnosis. The aim of this study is to evaluate the PET/CT diagnostic accuracy with dual time in the characterization of the solitary pulmonary nodule (NSP), analyzing the nodule histology and size. Methodology – There were 115 NSPs analyzed, a total of 110 patients, where 65 were malignant. Two images were acquired, one with an average time of 52 minutes and another with 125 minutes after the 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) injection. To analyze those images it was obtained the standard uptake value (SUVmax) and percentage of changes in SUVmax (%variação) were. Results – The %variation shows higher values of diagnostic accuracy than when analyzing SUVmax separately. However there are significant differences in histology and SUVmax, registering also an increase of SUVmax2 in malignant pathologies comparatively with SUVmax1. Conclusion – Dual time technique showed to be more efficient in NSP characterization than when analyzing only one image. Introdução – O cancro de pulmão/traqueia e brônquios é a principal causa de morte por neoplasia na União Europeia. A técnica de duas aquisições de imagem em tempos diferentes no Positron Emission Tomography/Computed Tomography (PET/CT) tem sido referenciada em alguns artigos como uma mais-valia no diagnóstico do cancro do pulmão. O objectivo deste estudo consiste em avaliar a eficiência diagnóstica do PET/CT com a aquisição das duas imagens em tempos diferentes na caracterização do nódulo solitário pulmonar (NSP), tendo em conta a histologia e o tamanho do nódulo. Metodologia – Foram analisados 115 NSP, num total de 110 pacientes, dos quais 65 nódulos eram malignos. Adquiriram-se duas imagens, a primeira a um tempo médio de 52 minutos e a segunda a um tempo médio de 125 minutos após administração do 18F-2-fluoro-2-deoxi-D-glucose (18F-FDG). Para a análise das imagens obteve-se o standard uptake value máximo (SUVmax) e a percentagem de variação dos SUVmax (%variação). Resultados – A %variação apresenta valores de eficiência diagnóstica superiores à análise dos SUVmax em separado. Existem também diferenças significativas na histologia e no SUVmax, registando-se um aumento do SUVmax2 comparativamente ao SUVmax1 nas patologias malignas. Conclusão – A técnica da aquisição de duas imagens em tempos diferentes mostrou ser mais eficaz na caracterização do NSP do que a análise de apenas uma imagem.Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa)2011-05-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.25758/set.334https://doi.org/10.25758/set.334Saúde e Tecnologia; No. 05 (2011): Maio 2011; 23-28Saúde & Tecnologia; N.º 05 (2011): Maio 2011; 23-281646-9704reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://journals.ipl.pt/stecnologia/article/view/710https://journals.ipl.pt/stecnologia/article/view/710/605Direitos de Autor (c) 2022 Saúde & Tecnologiainfo:eu-repo/semantics/openAccessGraça, AnaGarcia Bernardo, LuciaRafael Infante, JoséRayo Madrid, JuanVieira, Lina2023-01-13T08:30:15Zoai:journals.ipl.pt:article/710Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:21:30.582478Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Utility of the PET/CT in the characterization of the solitary pulmonary nodule Utilidade do PET/CT na caracterização do nódulo solitário pulmonar |
title |
Utility of the PET/CT in the characterization of the solitary pulmonary nodule |
spellingShingle |
Utility of the PET/CT in the characterization of the solitary pulmonary nodule Graça, Ana Duplo tempo Nódulo solitário pulmonar SUVmax %variação Dual time Solitary pulmonary nodule SUVmax %variation |
title_short |
Utility of the PET/CT in the characterization of the solitary pulmonary nodule |
title_full |
Utility of the PET/CT in the characterization of the solitary pulmonary nodule |
title_fullStr |
Utility of the PET/CT in the characterization of the solitary pulmonary nodule |
title_full_unstemmed |
Utility of the PET/CT in the characterization of the solitary pulmonary nodule |
title_sort |
Utility of the PET/CT in the characterization of the solitary pulmonary nodule |
author |
Graça, Ana |
author_facet |
Graça, Ana Garcia Bernardo, Lucia Rafael Infante, José Rayo Madrid, Juan Vieira, Lina |
author_role |
author |
author2 |
Garcia Bernardo, Lucia Rafael Infante, José Rayo Madrid, Juan Vieira, Lina |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Graça, Ana Garcia Bernardo, Lucia Rafael Infante, José Rayo Madrid, Juan Vieira, Lina |
dc.subject.por.fl_str_mv |
Duplo tempo Nódulo solitário pulmonar SUVmax %variação Dual time Solitary pulmonary nodule SUVmax %variation |
topic |
Duplo tempo Nódulo solitário pulmonar SUVmax %variação Dual time Solitary pulmonary nodule SUVmax %variation |
description |
Background – Cancer of the lung/trachea and bronchi is the leading cause of death from cancer in the European Union. Dual time in Positron Emission Tomography/Computed Tomography (PET/CT) technique has been referred to in some articles as a great value in pulmonary cancer diagnosis. The aim of this study is to evaluate the PET/CT diagnostic accuracy with dual time in the characterization of the solitary pulmonary nodule (NSP), analyzing the nodule histology and size. Methodology – There were 115 NSPs analyzed, a total of 110 patients, where 65 were malignant. Two images were acquired, one with an average time of 52 minutes and another with 125 minutes after the 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) injection. To analyze those images it was obtained the standard uptake value (SUVmax) and percentage of changes in SUVmax (%variação) were. Results – The %variation shows higher values of diagnostic accuracy than when analyzing SUVmax separately. However there are significant differences in histology and SUVmax, registering also an increase of SUVmax2 in malignant pathologies comparatively with SUVmax1. Conclusion – Dual time technique showed to be more efficient in NSP characterization than when analyzing only one image. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-05-15 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.25758/set.334 https://doi.org/10.25758/set.334 |
url |
https://doi.org/10.25758/set.334 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://journals.ipl.pt/stecnologia/article/view/710 https://journals.ipl.pt/stecnologia/article/view/710/605 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2022 Saúde & Tecnologia info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2022 Saúde & Tecnologia |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa) |
publisher.none.fl_str_mv |
Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa) |
dc.source.none.fl_str_mv |
Saúde e Tecnologia; No. 05 (2011): Maio 2011; 23-28 Saúde & Tecnologia; N.º 05 (2011): Maio 2011; 23-28 1646-9704 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130661969199104 |