Utility of the PET/CT in the characterization of the solitary pulmonary nodule

Detalhes bibliográficos
Autor(a) principal: Graça, Ana
Data de Publicação: 2011
Outros Autores: Garcia Bernardo, Lucia, Rafael Infante, José, Rayo Madrid, Juan, Vieira, Lina
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25758/set.334
Resumo: Background – Cancer of the lung/trachea and bronchi is the leading cause of death from cancer in the European Union. Dual time in Positron Emission Tomography/Computed Tomography (PET/CT) technique has been referred to in some articles as a great value in pulmonary cancer diagnosis. The aim of this study is to evaluate the PET/CT diagnostic accuracy with dual time in the characterization of the solitary pulmonary nodule (NSP), analyzing the nodule histology and size. Methodology – There were 115 NSPs analyzed, a total of 110 patients, where 65 were malignant. Two images were acquired, one with an average time of 52 minutes and another with 125 minutes after the 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) injection. To analyze those images it was obtained the standard uptake value (SUVmax) and percentage of changes in SUVmax (%variação) were. Results – The %variation shows higher values of diagnostic accuracy than when analyzing SUVmax separately. However there are significant differences in histology and SUVmax, registering also an increase of SUVmax2 in malignant pathologies comparatively with SUVmax1. Conclusion – Dual time technique showed to be more efficient in NSP characterization than when analyzing only one image. 
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spelling Utility of the PET/CT in the characterization of the solitary pulmonary noduleUtilidade do PET/CT na caracterização do nódulo solitário pulmonarDuplo tempoNódulo solitário pulmonarSUVmax%variaçãoDual timeSolitary pulmonary noduleSUVmax%variationBackground – Cancer of the lung/trachea and bronchi is the leading cause of death from cancer in the European Union. Dual time in Positron Emission Tomography/Computed Tomography (PET/CT) technique has been referred to in some articles as a great value in pulmonary cancer diagnosis. The aim of this study is to evaluate the PET/CT diagnostic accuracy with dual time in the characterization of the solitary pulmonary nodule (NSP), analyzing the nodule histology and size. Methodology – There were 115 NSPs analyzed, a total of 110 patients, where 65 were malignant. Two images were acquired, one with an average time of 52 minutes and another with 125 minutes after the 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) injection. To analyze those images it was obtained the standard uptake value (SUVmax) and percentage of changes in SUVmax (%variação) were. Results – The %variation shows higher values of diagnostic accuracy than when analyzing SUVmax separately. However there are significant differences in histology and SUVmax, registering also an increase of SUVmax2 in malignant pathologies comparatively with SUVmax1. Conclusion – Dual time technique showed to be more efficient in NSP characterization than when analyzing only one image. Introdução – O cancro de pulmão/traqueia e brônquios é a principal causa de morte por neoplasia na União Europeia. A técnica de duas aquisições de imagem em tempos diferentes no Positron Emission Tomography/Computed Tomography (PET/CT) tem sido referenciada em alguns artigos como uma mais-valia no diagnóstico do cancro do pulmão. O objectivo deste estudo consiste em avaliar a eficiência diagnóstica do PET/CT com a aquisição das duas imagens em tempos diferentes na caracterização do nódulo solitário pulmonar (NSP), tendo em conta a histologia e o tamanho do nódulo. Metodologia – Foram analisados 115 NSP, num total de 110 pacientes, dos quais 65 nódulos eram malignos. Adquiriram-se duas imagens, a primeira a um tempo médio de 52 minutos e a segunda a um tempo médio de 125 minutos após administração do 18F-2-fluoro-2-deoxi-D-glucose (18F-FDG). Para a análise das imagens obteve-se o standard uptake value máximo (SUVmax) e a percentagem de variação dos SUVmax (%variação). Resultados – A %variação apresenta valores de eficiência diagnóstica superiores à análise dos SUVmax em separado. Existem também diferenças significativas na histologia e no SUVmax, registando-se um aumento do SUVmax2 comparativamente ao SUVmax1 nas patologias malignas. Conclusão – A técnica da aquisição de duas imagens em tempos diferentes mostrou ser mais eficaz na caracterização do NSP do que a análise de apenas uma imagem.Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa)2011-05-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.25758/set.334https://doi.org/10.25758/set.334Saúde e Tecnologia; No. 05 (2011): Maio 2011; 23-28Saúde & Tecnologia; N.º 05 (2011): Maio 2011; 23-281646-9704reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://journals.ipl.pt/stecnologia/article/view/710https://journals.ipl.pt/stecnologia/article/view/710/605Direitos de Autor (c) 2022 Saúde & Tecnologiainfo:eu-repo/semantics/openAccessGraça, AnaGarcia Bernardo, LuciaRafael Infante, JoséRayo Madrid, JuanVieira, Lina2023-01-13T08:30:15Zoai:journals.ipl.pt:article/710Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:21:30.582478Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Utility of the PET/CT in the characterization of the solitary pulmonary nodule
Utilidade do PET/CT na caracterização do nódulo solitário pulmonar
title Utility of the PET/CT in the characterization of the solitary pulmonary nodule
spellingShingle Utility of the PET/CT in the characterization of the solitary pulmonary nodule
Graça, Ana
Duplo tempo
Nódulo solitário pulmonar
SUVmax
%variação
Dual time
Solitary pulmonary nodule
SUVmax
%variation
title_short Utility of the PET/CT in the characterization of the solitary pulmonary nodule
title_full Utility of the PET/CT in the characterization of the solitary pulmonary nodule
title_fullStr Utility of the PET/CT in the characterization of the solitary pulmonary nodule
title_full_unstemmed Utility of the PET/CT in the characterization of the solitary pulmonary nodule
title_sort Utility of the PET/CT in the characterization of the solitary pulmonary nodule
author Graça, Ana
author_facet Graça, Ana
Garcia Bernardo, Lucia
Rafael Infante, José
Rayo Madrid, Juan
Vieira, Lina
author_role author
author2 Garcia Bernardo, Lucia
Rafael Infante, José
Rayo Madrid, Juan
Vieira, Lina
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Graça, Ana
Garcia Bernardo, Lucia
Rafael Infante, José
Rayo Madrid, Juan
Vieira, Lina
dc.subject.por.fl_str_mv Duplo tempo
Nódulo solitário pulmonar
SUVmax
%variação
Dual time
Solitary pulmonary nodule
SUVmax
%variation
topic Duplo tempo
Nódulo solitário pulmonar
SUVmax
%variação
Dual time
Solitary pulmonary nodule
SUVmax
%variation
description Background – Cancer of the lung/trachea and bronchi is the leading cause of death from cancer in the European Union. Dual time in Positron Emission Tomography/Computed Tomography (PET/CT) technique has been referred to in some articles as a great value in pulmonary cancer diagnosis. The aim of this study is to evaluate the PET/CT diagnostic accuracy with dual time in the characterization of the solitary pulmonary nodule (NSP), analyzing the nodule histology and size. Methodology – There were 115 NSPs analyzed, a total of 110 patients, where 65 were malignant. Two images were acquired, one with an average time of 52 minutes and another with 125 minutes after the 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) injection. To analyze those images it was obtained the standard uptake value (SUVmax) and percentage of changes in SUVmax (%variação) were. Results – The %variation shows higher values of diagnostic accuracy than when analyzing SUVmax separately. However there are significant differences in histology and SUVmax, registering also an increase of SUVmax2 in malignant pathologies comparatively with SUVmax1. Conclusion – Dual time technique showed to be more efficient in NSP characterization than when analyzing only one image. 
publishDate 2011
dc.date.none.fl_str_mv 2011-05-15
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.25758/set.334
https://doi.org/10.25758/set.334
url https://doi.org/10.25758/set.334
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://journals.ipl.pt/stecnologia/article/view/710
https://journals.ipl.pt/stecnologia/article/view/710/605
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2022 Saúde & Tecnologia
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2022 Saúde & Tecnologia
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa)
publisher.none.fl_str_mv Escola Superior de Tecnologia da Saúde de Lisboa (Instituto Politécnico de Lisboa)
dc.source.none.fl_str_mv Saúde e Tecnologia; No. 05 (2011): Maio 2011; 23-28
Saúde & Tecnologia; N.º 05 (2011): Maio 2011; 23-28
1646-9704
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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