In sickness and in health: the oxygen reactive species and the bone

Detalhes bibliográficos
Autor(a) principal: Reis, Joana
Data de Publicação: 2021
Outros Autores: Ramos, António
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/20.500.11960/3331
Resumo: Oxidative stress plays a central role in physiological and pathological bone conditions. Its role in signalment and control of bone cell population differentiation, activity, and fate is increasingly recognized. The possibilities of its use and manipulation with therapeutic goals are virtually unending. However, how redox balance interplays with the response to mechanical stimuli is yet to be fully understood. The present work summarizes current knowledge on these aspects, in an integrative and broad introductory perspective.
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spelling In sickness and in health: the oxygen reactive species and the boneOxidative stressBoneMechanobiologyRedox balanceMechanotransductionOxidative stress plays a central role in physiological and pathological bone conditions. Its role in signalment and control of bone cell population differentiation, activity, and fate is increasingly recognized. The possibilities of its use and manipulation with therapeutic goals are virtually unending. However, how redox balance interplays with the response to mechanical stimuli is yet to be fully understood. The present work summarizes current knowledge on these aspects, in an integrative and broad introductory perspective.2023-05-29T15:30:20Z2021-11-23T00:00:00Z2021-11-232022-12-07T15:43:27Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/20.500.11960/3331por2296-418510.3389/fbioe.2021.745911Reis, JoanaRamos, Antónioinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-06-01T06:45:13Zoai:repositorio.ipvc.pt:20.500.11960/3331Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:59:33.901034Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv In sickness and in health: the oxygen reactive species and the bone
title In sickness and in health: the oxygen reactive species and the bone
spellingShingle In sickness and in health: the oxygen reactive species and the bone
Reis, Joana
Oxidative stress
Bone
Mechanobiology
Redox balance
Mechanotransduction
title_short In sickness and in health: the oxygen reactive species and the bone
title_full In sickness and in health: the oxygen reactive species and the bone
title_fullStr In sickness and in health: the oxygen reactive species and the bone
title_full_unstemmed In sickness and in health: the oxygen reactive species and the bone
title_sort In sickness and in health: the oxygen reactive species and the bone
author Reis, Joana
author_facet Reis, Joana
Ramos, António
author_role author
author2 Ramos, António
author2_role author
dc.contributor.author.fl_str_mv Reis, Joana
Ramos, António
dc.subject.por.fl_str_mv Oxidative stress
Bone
Mechanobiology
Redox balance
Mechanotransduction
topic Oxidative stress
Bone
Mechanobiology
Redox balance
Mechanotransduction
description Oxidative stress plays a central role in physiological and pathological bone conditions. Its role in signalment and control of bone cell population differentiation, activity, and fate is increasingly recognized. The possibilities of its use and manipulation with therapeutic goals are virtually unending. However, how redox balance interplays with the response to mechanical stimuli is yet to be fully understood. The present work summarizes current knowledge on these aspects, in an integrative and broad introductory perspective.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-23T00:00:00Z
2021-11-23
2022-12-07T15:43:27Z
2023-05-29T15:30:20Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/20.500.11960/3331
url http://hdl.handle.net/20.500.11960/3331
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 2296-4185
10.3389/fbioe.2021.745911
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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