Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.18/3515 |
Resumo: | Dientamoeba fragilis is an inhabitant of human gastrointestinal tract with a worldwide distribution. The first description considered this protozoan a rare and harmless commensal, since then it has struggled to gain recognition as a pathogen. Commercial multiplex real-time PCR was used to detect D. fragilis in fecal samples from hospitalized children (⩽18 years) with acute gastrointestinal disease, admitted to two hospitals of Lisbon area, with different demographic characteristics. A total of 176 children were studied, 103 (58·5%) male, 144 (81·8%) children between 0 and 5 years and 32 (18·2%) above 6 years old. The overall protozoa frequency considering the four tested microorganisms were 8·5% (15/176), and the most frequently found protozoan was D. fragilis, 6·3% (11/176). Dientamoeba fragilis frequency was higher among older children (21·9%), than younger children (2·8%), and greater in boys (6·8%) than in girls (5·5%). All positive children presented with diarrhoea associated with vomiting, fever and abdominal pain. Infection was associated with the age of children (P < 0·001), school attendance (P = 0·002) and consumption of certain foods (P = 0·014), e.g. cakes with crème and ham. The frequency of diantamoebiasis found in a cohort of hospitalized Portuguese children, with acute gastrointestinal disease, could be considered a very high value when compared with the protozoan frequency normally associated with this pathology. |
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Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013Cambridge University PressDientamoeba fragilisAcute GastroenteritisFrequencyHospitalized ChildrenPortugalInfecções GastrointestinaisDientamoeba fragilis is an inhabitant of human gastrointestinal tract with a worldwide distribution. The first description considered this protozoan a rare and harmless commensal, since then it has struggled to gain recognition as a pathogen. Commercial multiplex real-time PCR was used to detect D. fragilis in fecal samples from hospitalized children (⩽18 years) with acute gastrointestinal disease, admitted to two hospitals of Lisbon area, with different demographic characteristics. A total of 176 children were studied, 103 (58·5%) male, 144 (81·8%) children between 0 and 5 years and 32 (18·2%) above 6 years old. The overall protozoa frequency considering the four tested microorganisms were 8·5% (15/176), and the most frequently found protozoan was D. fragilis, 6·3% (11/176). Dientamoeba fragilis frequency was higher among older children (21·9%), than younger children (2·8%), and greater in boys (6·8%) than in girls (5·5%). All positive children presented with diarrhoea associated with vomiting, fever and abdominal pain. Infection was associated with the age of children (P < 0·001), school attendance (P = 0·002) and consumption of certain foods (P = 0·014), e.g. cakes with crème and ham. The frequency of diantamoebiasis found in a cohort of hospitalized Portuguese children, with acute gastrointestinal disease, could be considered a very high value when compared with the protozoan frequency normally associated with this pathology.Cambridge University PressRepositório Científico do Instituto Nacional de SaúdeJúlio, C.Furtado, CristinaRocha, R.Escobar, C.Brito, M.J.Oleastro, Mónica2016-04-01T00:30:10Z2015-092015-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/3515engParasitology. 2015 Sep;142(11):1398-403. doi: 10.1017/S0031182015000906. Epub 2015 Jul 210031-182010.1017/S0031182015000906info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:39:48Zoai:repositorio.insa.pt:10400.18/3515Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:38:20.619915Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013 Cambridge University Press |
title |
Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013 |
spellingShingle |
Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013 Júlio, C. Dientamoeba fragilis Acute Gastroenteritis Frequency Hospitalized Children Portugal Infecções Gastrointestinais |
title_short |
Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013 |
title_full |
Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013 |
title_fullStr |
Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013 |
title_full_unstemmed |
Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013 |
title_sort |
Detection of Dientamoeba fragilis in Portuguese children with acute gastroenteritis between 2011 and 2013 |
author |
Júlio, C. |
author_facet |
Júlio, C. Furtado, Cristina Rocha, R. Escobar, C. Brito, M.J. Oleastro, Mónica |
author_role |
author |
author2 |
Furtado, Cristina Rocha, R. Escobar, C. Brito, M.J. Oleastro, Mónica |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
dc.contributor.author.fl_str_mv |
Júlio, C. Furtado, Cristina Rocha, R. Escobar, C. Brito, M.J. Oleastro, Mónica |
dc.subject.por.fl_str_mv |
Dientamoeba fragilis Acute Gastroenteritis Frequency Hospitalized Children Portugal Infecções Gastrointestinais |
topic |
Dientamoeba fragilis Acute Gastroenteritis Frequency Hospitalized Children Portugal Infecções Gastrointestinais |
description |
Dientamoeba fragilis is an inhabitant of human gastrointestinal tract with a worldwide distribution. The first description considered this protozoan a rare and harmless commensal, since then it has struggled to gain recognition as a pathogen. Commercial multiplex real-time PCR was used to detect D. fragilis in fecal samples from hospitalized children (⩽18 years) with acute gastrointestinal disease, admitted to two hospitals of Lisbon area, with different demographic characteristics. A total of 176 children were studied, 103 (58·5%) male, 144 (81·8%) children between 0 and 5 years and 32 (18·2%) above 6 years old. The overall protozoa frequency considering the four tested microorganisms were 8·5% (15/176), and the most frequently found protozoan was D. fragilis, 6·3% (11/176). Dientamoeba fragilis frequency was higher among older children (21·9%), than younger children (2·8%), and greater in boys (6·8%) than in girls (5·5%). All positive children presented with diarrhoea associated with vomiting, fever and abdominal pain. Infection was associated with the age of children (P < 0·001), school attendance (P = 0·002) and consumption of certain foods (P = 0·014), e.g. cakes with crème and ham. The frequency of diantamoebiasis found in a cohort of hospitalized Portuguese children, with acute gastrointestinal disease, could be considered a very high value when compared with the protozoan frequency normally associated with this pathology. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-09 2015-09-01T00:00:00Z 2016-04-01T00:30:10Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/3515 |
url |
http://hdl.handle.net/10400.18/3515 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Parasitology. 2015 Sep;142(11):1398-403. doi: 10.1017/S0031182015000906. Epub 2015 Jul 21 0031-1820 10.1017/S0031182015000906 |
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info:eu-repo/semantics/embargoedAccess |
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embargoedAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Cambridge University Press |
publisher.none.fl_str_mv |
Cambridge University Press |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799132120186093568 |