Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/77071 |
Resumo: | Hydrogels are known for their leading role in biomaterial systems involving pharmaceuticals that fascinate material scientists to work on the wide variety of biomedical applications. The physical and mechanical properties of hydrogels, along with their biodegradability and biocompatibility characteristics, have made them an attractive and flexible tool with various applications such as imaging, diagnosis and treatment. The water-cherishing nature of hydrogels and their capacity to swell—contingent upon a few ecological signals or the simple presence of water—is alluring for drug conveyance applications. Currently, there are several problems relating to drug delivery, to which hydrogel may provide a possible solution. Hence, it is pertinent to collate updates on hydrogels pertaining to biomedical applications. The primary objective of this review article is to garner information regarding classification, properties, methods of preparations, and of the polymers used with particular emphasis on injectable hydrogels. This review also covers the regulatory and other commerce specific information. Further, it enlists several patents and clinical trials of hydrogels with related indications and offers a consolidated resource for all facets associated with the biomedical hydrogels. |
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Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive reviewHydrogelBiomaterialPatentsInjectableRegulatoryDrug deliveryScience & TechnologyHydrogels are known for their leading role in biomaterial systems involving pharmaceuticals that fascinate material scientists to work on the wide variety of biomedical applications. The physical and mechanical properties of hydrogels, along with their biodegradability and biocompatibility characteristics, have made them an attractive and flexible tool with various applications such as imaging, diagnosis and treatment. The water-cherishing nature of hydrogels and their capacity to swell—contingent upon a few ecological signals or the simple presence of water—is alluring for drug conveyance applications. Currently, there are several problems relating to drug delivery, to which hydrogel may provide a possible solution. Hence, it is pertinent to collate updates on hydrogels pertaining to biomedical applications. The primary objective of this review article is to garner information regarding classification, properties, methods of preparations, and of the polymers used with particular emphasis on injectable hydrogels. This review also covers the regulatory and other commerce specific information. Further, it enlists several patents and clinical trials of hydrogels with related indications and offers a consolidated resource for all facets associated with the biomedical hydrogels.The authors are highly grateful towards Jamia Hamdard and DST for providing support in the form of DST PURSE. In addition, we would to thank Universiti Malaya for providing the facilities.Multidisciplinary Digital Publishing Institute (MDPI)Universidade do MinhoMohapatra, SradhanjaliMirza, Mohd. AamirHilles, Ayah RebhiZakir, FoziyahGomes, Andreia CAnsari, Mohammad JavedIqbal, ZeenatMahmood, Syed2021-11-122021-11-12T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/77071engMohapatra, S.; Mirza, M.A.; Hilles, A.R.; Zakir, F.; Gomes, A.C.; Ansari, M.J.; Iqbal, Z.; Mahmood, S. Biomedical Application, Patent Repository, Clinical Trial and Regulatory Updates on Hydrogel: An Extensive Review. Gels 2021, 7, 207. https://doi.org/10.3390/gels70402072310-286110.3390/gels7040207207https://www.mdpi.com/2310-2861/7/4/207info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:51:12Zoai:repositorium.sdum.uminho.pt:1822/77071Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:50:03.021061Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review |
title |
Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review |
spellingShingle |
Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review Mohapatra, Sradhanjali Hydrogel Biomaterial Patents Injectable Regulatory Drug delivery Science & Technology |
title_short |
Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review |
title_full |
Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review |
title_fullStr |
Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review |
title_full_unstemmed |
Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review |
title_sort |
Biomedical application, patent repository, clinical trial and regulatory updates on hydrogel: an extensive review |
author |
Mohapatra, Sradhanjali |
author_facet |
Mohapatra, Sradhanjali Mirza, Mohd. Aamir Hilles, Ayah Rebhi Zakir, Foziyah Gomes, Andreia C Ansari, Mohammad Javed Iqbal, Zeenat Mahmood, Syed |
author_role |
author |
author2 |
Mirza, Mohd. Aamir Hilles, Ayah Rebhi Zakir, Foziyah Gomes, Andreia C Ansari, Mohammad Javed Iqbal, Zeenat Mahmood, Syed |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Mohapatra, Sradhanjali Mirza, Mohd. Aamir Hilles, Ayah Rebhi Zakir, Foziyah Gomes, Andreia C Ansari, Mohammad Javed Iqbal, Zeenat Mahmood, Syed |
dc.subject.por.fl_str_mv |
Hydrogel Biomaterial Patents Injectable Regulatory Drug delivery Science & Technology |
topic |
Hydrogel Biomaterial Patents Injectable Regulatory Drug delivery Science & Technology |
description |
Hydrogels are known for their leading role in biomaterial systems involving pharmaceuticals that fascinate material scientists to work on the wide variety of biomedical applications. The physical and mechanical properties of hydrogels, along with their biodegradability and biocompatibility characteristics, have made them an attractive and flexible tool with various applications such as imaging, diagnosis and treatment. The water-cherishing nature of hydrogels and their capacity to swell—contingent upon a few ecological signals or the simple presence of water—is alluring for drug conveyance applications. Currently, there are several problems relating to drug delivery, to which hydrogel may provide a possible solution. Hence, it is pertinent to collate updates on hydrogels pertaining to biomedical applications. The primary objective of this review article is to garner information regarding classification, properties, methods of preparations, and of the polymers used with particular emphasis on injectable hydrogels. This review also covers the regulatory and other commerce specific information. Further, it enlists several patents and clinical trials of hydrogels with related indications and offers a consolidated resource for all facets associated with the biomedical hydrogels. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-11-12 2021-11-12T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/77071 |
url |
http://hdl.handle.net/1822/77071 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Mohapatra, S.; Mirza, M.A.; Hilles, A.R.; Zakir, F.; Gomes, A.C.; Ansari, M.J.; Iqbal, Z.; Mahmood, S. Biomedical Application, Patent Repository, Clinical Trial and Regulatory Updates on Hydrogel: An Extensive Review. Gels 2021, 7, 207. https://doi.org/10.3390/gels7040207 2310-2861 10.3390/gels7040207 207 https://www.mdpi.com/2310-2861/7/4/207 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute (MDPI) |
publisher.none.fl_str_mv |
Multidisciplinary Digital Publishing Institute (MDPI) |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133084194439168 |