Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)

Detalhes bibliográficos
Autor(a) principal: Gonçalves-Pereira, J.
Data de Publicação: 2013
Outros Autores: Povoa, Pedro, Lobo, C., Carneiro, A. H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/149793
Resumo: Funding Information: This work was mostly supported by an unrestricted grant from ASSUCIP (Associação dos Amigos da Unidade de Cuidados Intensivos Polivalente, Hospital Geral de Santo António, Porto, Portugal) as well as by grants from GIS (Grupo de Infecção e Sepsis, Hospital de São João, Porto, Portugal) Merck Sharp & Dohme and Eli Lilly. CL received a grant from Fundação para a Ciência e Tecnologia (PIC/IC/83312/2007). All other authors report that they have no other competing interests to declare related to the topic of this manuscript.
id RCAP_b0b07217ebb3ba0bf5cf2272b75b384a
oai_identifier_str oai:run.unl.pt:10362/149793
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)Blood culturesBloodstream infectionCommunity-acquired sepsisIntensive-care unitSeptic shockMicrobiology (medical)Infectious DiseasesSDG 3 - Good Health and Well-beingFunding Information: This work was mostly supported by an unrestricted grant from ASSUCIP (Associação dos Amigos da Unidade de Cuidados Intensivos Polivalente, Hospital Geral de Santo António, Porto, Portugal) as well as by grants from GIS (Grupo de Infecção e Sepsis, Hospital de São João, Porto, Portugal) Merck Sharp & Dohme and Eli Lilly. CL received a grant from Fundação para a Ciência e Tecnologia (PIC/IC/83312/2007). All other authors report that they have no other competing interests to declare related to the topic of this manuscript.Clin Microbiol Infect 2013; 19: 242-248 The impact of bloodstream infection (BSI) on admission to hospital on the outcome of patients with community-acquired sepsis (CAS) admitted to intensive-care units (ICU) is largely unknown. We selected 803 adult patients consecutively admitted with CAS to one of 17 Portuguese ICU, in whom blood cultures were collected before initiation of antibiotic therapy during a 12-month period. A BSI was identified on hospital admission in 160 (19.9%) patients. Those with and without BSI had similar mean Simplified Acute Physiology Score (SAPS) II and age. The presence of BSI was independently associated with mortality in ICU (adjusted odds ratio 1.86; 95% confidence interval 1.20-2.89; p 0.005). On the 4th day in ICU, patients with BSI were found to be significantly more dependent on vasopressor support (p 0.002) but not on ventilatory support. Cumulative ICU mortality was significantly higher in BSI patients from the 9th day onwards. A seasonal variation of BSI isolates was noted: gram-negative BSI were more common in the summer, whereas in the winter, gram-positive infections were more frequent (p 0.024), without mortality differences.Centro de Estudos de Doenças Crónicas (CEDOC)NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNGonçalves-Pereira, J.Povoa, PedroLobo, C.Carneiro, A. H.2023-02-27T22:22:48Z2013-032013-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://hdl.handle.net/10362/149793eng1198-743XPURE: 48423237https://doi.org/10.1111/j.1469-0691.2012.03776.xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:31:38Zoai:run.unl.pt:10362/149793Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:53:51.695377Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)
title Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)
spellingShingle Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)
Gonçalves-Pereira, J.
Blood cultures
Bloodstream infection
Community-acquired sepsis
Intensive-care unit
Septic shock
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
title_short Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)
title_full Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)
title_fullStr Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)
title_full_unstemmed Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)
title_sort Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study)
author Gonçalves-Pereira, J.
author_facet Gonçalves-Pereira, J.
Povoa, Pedro
Lobo, C.
Carneiro, A. H.
author_role author
author2 Povoa, Pedro
Lobo, C.
Carneiro, A. H.
author2_role author
author
author
dc.contributor.none.fl_str_mv Centro de Estudos de Doenças Crónicas (CEDOC)
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Gonçalves-Pereira, J.
Povoa, Pedro
Lobo, C.
Carneiro, A. H.
dc.subject.por.fl_str_mv Blood cultures
Bloodstream infection
Community-acquired sepsis
Intensive-care unit
Septic shock
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
topic Blood cultures
Bloodstream infection
Community-acquired sepsis
Intensive-care unit
Septic shock
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
description Funding Information: This work was mostly supported by an unrestricted grant from ASSUCIP (Associação dos Amigos da Unidade de Cuidados Intensivos Polivalente, Hospital Geral de Santo António, Porto, Portugal) as well as by grants from GIS (Grupo de Infecção e Sepsis, Hospital de São João, Porto, Portugal) Merck Sharp & Dohme and Eli Lilly. CL received a grant from Fundação para a Ciência e Tecnologia (PIC/IC/83312/2007). All other authors report that they have no other competing interests to declare related to the topic of this manuscript.
publishDate 2013
dc.date.none.fl_str_mv 2013-03
2013-03-01T00:00:00Z
2023-02-27T22:22:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/149793
url http://hdl.handle.net/10362/149793
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1198-743X
PURE: 48423237
https://doi.org/10.1111/j.1469-0691.2012.03776.x
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799138128877846528

Registros relacionados