Mesalazine induced tubulointersticial nephritis
Main Author: | |
---|---|
Publication Date: | 2015 |
Other Authors: | , , , , , |
Format: | Article |
Language: | eng |
Source: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Download full: | http://hdl.handle.net/10400.16/1926 |
Summary: | Inflammatory bowel disease and its various treatments may affect the kidney in several ways tubulointersticial nephritis is a rare but serious complication of longer-term mesalazine use. There are few cases reported in the literature. We report the first two cases of mesalazine-induced tubulointersticial nephritis, recently diagnosed in our department. The first one refers to a patient with ulcerous colitis and the second one to a patient with Crohn’s disease. Then the authors present a review of literature about the renal involvement in the inflammatory bowel disease. New cases of mesalazine nephrotoxicity should be reported to allow more accurate incidence estimation of this serious adverse effect. Routine monitoring of renal function is simple, inexpensive and allows an early diagnosis of this complication |
id |
RCAP_b0cf7a543b46defc5d37437c3c44ef35 |
---|---|
oai_identifier_str |
oai:repositorio.chporto.pt:10400.16/1926 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Mesalazine induced tubulointersticial nephritisNefrite tubulointersticial associada à mesalazinaInflammatory bowel diseasekidney diseasemesalazinetubulointersticial nephritisDoença inflamatória intestinaldoença renalnefrite tubulointersticialInflammatory bowel disease and its various treatments may affect the kidney in several ways tubulointersticial nephritis is a rare but serious complication of longer-term mesalazine use. There are few cases reported in the literature. We report the first two cases of mesalazine-induced tubulointersticial nephritis, recently diagnosed in our department. The first one refers to a patient with ulcerous colitis and the second one to a patient with Crohn’s disease. Then the authors present a review of literature about the renal involvement in the inflammatory bowel disease. New cases of mesalazine nephrotoxicity should be reported to allow more accurate incidence estimation of this serious adverse effect. Routine monitoring of renal function is simple, inexpensive and allows an early diagnosis of this complicationA doença inflamatória intestinal e as terapêuticas que lhe estão associadas podem afetar o rim de várias formas. A nefrite tubulointersticial é uma complicação rara, mas potencialmente grave inerente à terapêutica com mesalazina. Há alguns casos descritos na literatura. Os autores descrevem os dois primeiros casos de nefrite tubulointersticial associados ao uso de mesalazina, recentemente diagnosticados no nosso Serviço; um deles num doente com colite ulcerosa, outro num doente com doença de Crohn. Apresentam uma revisão da literatura sobre o atingimento renal na doença inflamatória intestinal. Os casos de nefrotoxicidade associada à mesalazina devem continuar a ser descritos para permitir estabelecer uma incidência mais precisa desde efeito adverso. A monitorização da função renal durante o tratamento é simples, barata e pode ajudar a diagnosticar precocemente esta complicaçãoSociedade Portuguesa de NefrologiaRepositório Científico do Centro Hospitalar Universitário de Santo AntónioCampos, A.Santos, S.Santos, J.Malheiro, J.Lobato, L.Vizcaíno, J.Cabrita, A.2016-04-26T11:34:47Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/1926engPort J Nephrol Hypert 2015; 29(2): 158-1642183-1289info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-20T10:58:10Zoai:repositorio.chporto.pt:10400.16/1926Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:38:14.417783Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Mesalazine induced tubulointersticial nephritis Nefrite tubulointersticial associada à mesalazina |
title |
Mesalazine induced tubulointersticial nephritis |
spellingShingle |
Mesalazine induced tubulointersticial nephritis Campos, A. Inflammatory bowel disease kidney disease mesalazine tubulointersticial nephritis Doença inflamatória intestinal doença renal nefrite tubulointersticial |
title_short |
Mesalazine induced tubulointersticial nephritis |
title_full |
Mesalazine induced tubulointersticial nephritis |
title_fullStr |
Mesalazine induced tubulointersticial nephritis |
title_full_unstemmed |
Mesalazine induced tubulointersticial nephritis |
title_sort |
Mesalazine induced tubulointersticial nephritis |
author |
Campos, A. |
author_facet |
Campos, A. Santos, S. Santos, J. Malheiro, J. Lobato, L. Vizcaíno, J. Cabrita, A. |
author_role |
author |
author2 |
Santos, S. Santos, J. Malheiro, J. Lobato, L. Vizcaíno, J. Cabrita, A. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Centro Hospitalar Universitário de Santo António |
dc.contributor.author.fl_str_mv |
Campos, A. Santos, S. Santos, J. Malheiro, J. Lobato, L. Vizcaíno, J. Cabrita, A. |
dc.subject.por.fl_str_mv |
Inflammatory bowel disease kidney disease mesalazine tubulointersticial nephritis Doença inflamatória intestinal doença renal nefrite tubulointersticial |
topic |
Inflammatory bowel disease kidney disease mesalazine tubulointersticial nephritis Doença inflamatória intestinal doença renal nefrite tubulointersticial |
description |
Inflammatory bowel disease and its various treatments may affect the kidney in several ways tubulointersticial nephritis is a rare but serious complication of longer-term mesalazine use. There are few cases reported in the literature. We report the first two cases of mesalazine-induced tubulointersticial nephritis, recently diagnosed in our department. The first one refers to a patient with ulcerous colitis and the second one to a patient with Crohn’s disease. Then the authors present a review of literature about the renal involvement in the inflammatory bowel disease. New cases of mesalazine nephrotoxicity should be reported to allow more accurate incidence estimation of this serious adverse effect. Routine monitoring of renal function is simple, inexpensive and allows an early diagnosis of this complication |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015 2015-01-01T00:00:00Z 2016-04-26T11:34:47Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.16/1926 |
url |
http://hdl.handle.net/10400.16/1926 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Port J Nephrol Hypert 2015; 29(2): 158-164 2183-1289 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Nefrologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Nefrologia |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799133644067962880 |