Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review

Detalhes bibliográficos
Autor(a) principal: Raimundo Fernandes, S
Data de Publicação: 2017
Outros Autores: Baldaia, C, Pinto Marques, H, Tortosa, F, Ramalho, F
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/2730
Resumo: Clear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.
id RCAP_b15e282ac2ec4f43d8d44a7f571a0126
oai_identifier_str oai:repositorio.chlc.min-saude.pt:10400.17/2730
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature ReviewCHLC CHBPTAdenocarcinoma, Clear Cell/diagnosisAdenocarcinoma, Clear Cell/pathologyBile Duct Neoplasms/diagnosisBile Duct Neoplasms/pathologyBile Ducts, Intrahepatic/pathologyCholangiocarcinoma/diagnosisCholangiocarcinoma/pathologyClear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.Sociedad Española de Patologia DigestivaRepositório do Centro Hospitalar Universitário de Lisboa Central, EPERaimundo Fernandes, SBaldaia, CPinto Marques, HTortosa, FRamalho, F2017-07-20T15:39:38Z2017-052017-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2730engRev Esp Enferm Dig. 2017 May;109(5):382-38510.17235/reed.2017.4239/2016info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:39:21Zoai:repositorio.chlc.min-saude.pt:10400.17/2730Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:20:03.951652Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review
title Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review
spellingShingle Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review
Raimundo Fernandes, S
CHLC CHBPT
Adenocarcinoma, Clear Cell/diagnosis
Adenocarcinoma, Clear Cell/pathology
Bile Duct Neoplasms/diagnosis
Bile Duct Neoplasms/pathology
Bile Ducts, Intrahepatic/pathology
Cholangiocarcinoma/diagnosis
Cholangiocarcinoma/pathology
title_short Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review
title_full Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review
title_fullStr Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review
title_full_unstemmed Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review
title_sort Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Case Report and Literature Review
author Raimundo Fernandes, S
author_facet Raimundo Fernandes, S
Baldaia, C
Pinto Marques, H
Tortosa, F
Ramalho, F
author_role author
author2 Baldaia, C
Pinto Marques, H
Tortosa, F
Ramalho, F
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Raimundo Fernandes, S
Baldaia, C
Pinto Marques, H
Tortosa, F
Ramalho, F
dc.subject.por.fl_str_mv CHLC CHBPT
Adenocarcinoma, Clear Cell/diagnosis
Adenocarcinoma, Clear Cell/pathology
Bile Duct Neoplasms/diagnosis
Bile Duct Neoplasms/pathology
Bile Ducts, Intrahepatic/pathology
Cholangiocarcinoma/diagnosis
Cholangiocarcinoma/pathology
topic CHLC CHBPT
Adenocarcinoma, Clear Cell/diagnosis
Adenocarcinoma, Clear Cell/pathology
Bile Duct Neoplasms/diagnosis
Bile Duct Neoplasms/pathology
Bile Ducts, Intrahepatic/pathology
Cholangiocarcinoma/diagnosis
Cholangiocarcinoma/pathology
description Clear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.
publishDate 2017
dc.date.none.fl_str_mv 2017-07-20T15:39:38Z
2017-05
2017-05-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/2730
url http://hdl.handle.net/10400.17/2730
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rev Esp Enferm Dig. 2017 May;109(5):382-385
10.17235/reed.2017.4239/2016
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedad Española de Patologia Digestiva
publisher.none.fl_str_mv Sociedad Española de Patologia Digestiva
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799131297015136256

Registros relacionados