Can dengue virus be sexually transmitted?

Detalhes bibliográficos
Autor(a) principal: Grobusch, Martin P.
Data de Publicação: 2020
Outros Autores: van der Fluit, Karin S., Stijnis, Cornelis, De Pijper, Cornelis A., Hanscheid, Thomas, Gautret, Philippe, Schlagenhauf, Patricia, Goorhuis, Abraham
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/49740
Resumo: © 2020 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
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spelling Can dengue virus be sexually transmitted?DENVDengueSemenSexual transmissionVaginal fluid© 2020 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)It has been well documented that Zika virus (ZIKV) can be sexually transmitted. Dengue virus (DENV) shows many similarities with ZIKV; both belong to the genus Flavivirus and share the same main vector route of transmission. Moreover, they share overall architectural features on a molecular level, with a highly similar structure and distinctive insertions, deletions and mutations of their respective E proteins, and it has been suggested that they use a common pathophysiological pathway. In view of similarities with other sexually transmissible viruses, the question arises as to whether DENV could also be sexually transmissible. Limited animal model data do not suggest otherwise. The presence of dengue virus in - and human-to-human, non-vector transmission from - various bodily fluids other than semen or vaginal secretions has been documented anecdotally. Several anecdotal reports described prolonged presence of DENV in semen, urine and vaginal secretions. In 2019, two cases of likely sexual transmission were reported from Spain and South Korea, respectively. We discuss the evidence for and against a relevant DENV sexual transmission potential, highlight controversies and propose a future research agenda on this issue.ElsevierRepositório da Universidade de LisboaGrobusch, Martin P.van der Fluit, Karin S.Stijnis, CornelisDe Pijper, Cornelis A.Hanscheid, ThomasGautret, PhilippeSchlagenhauf, PatriciaGoorhuis, Abraham2021-09-30T15:15:44Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/49740engTravel Med Infect Dis. 2020 Nov-Dec;38:1017531477-893910.1016/j.tmaid.2020.1017531873-0442info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-11-20T18:09:25Zoai:repositorio.ul.pt:10451/49740Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-11-20T18:09:25Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Can dengue virus be sexually transmitted?
title Can dengue virus be sexually transmitted?
spellingShingle Can dengue virus be sexually transmitted?
Grobusch, Martin P.
DENV
Dengue
Semen
Sexual transmission
Vaginal fluid
title_short Can dengue virus be sexually transmitted?
title_full Can dengue virus be sexually transmitted?
title_fullStr Can dengue virus be sexually transmitted?
title_full_unstemmed Can dengue virus be sexually transmitted?
title_sort Can dengue virus be sexually transmitted?
author Grobusch, Martin P.
author_facet Grobusch, Martin P.
van der Fluit, Karin S.
Stijnis, Cornelis
De Pijper, Cornelis A.
Hanscheid, Thomas
Gautret, Philippe
Schlagenhauf, Patricia
Goorhuis, Abraham
author_role author
author2 van der Fluit, Karin S.
Stijnis, Cornelis
De Pijper, Cornelis A.
Hanscheid, Thomas
Gautret, Philippe
Schlagenhauf, Patricia
Goorhuis, Abraham
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Grobusch, Martin P.
van der Fluit, Karin S.
Stijnis, Cornelis
De Pijper, Cornelis A.
Hanscheid, Thomas
Gautret, Philippe
Schlagenhauf, Patricia
Goorhuis, Abraham
dc.subject.por.fl_str_mv DENV
Dengue
Semen
Sexual transmission
Vaginal fluid
topic DENV
Dengue
Semen
Sexual transmission
Vaginal fluid
description © 2020 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2021-09-30T15:15:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/49740
url http://hdl.handle.net/10451/49740
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Travel Med Infect Dis. 2020 Nov-Dec;38:101753
1477-8939
10.1016/j.tmaid.2020.101753
1873-0442
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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