Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney

Detalhes bibliográficos
Autor(a) principal: Botelho, Ana R.
Data de Publicação: 2023
Outros Autores: Silva, Hugo F., Martins, Inês S., Carneiro, Isa, Carvalho, Sónia D., Henrique, Rui M., Tuchin, Valery V., Oliveira, Luís M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/22542
Resumo: A fast calculation method was used to obtain the spectral optical properties of human normal and pathological (chromophobe renal cell carcinoma) kidney tissues. Using total transmittance, total reflectance and collimated transmittance spectra acquired from ex vivo kidney samples, the spectral optical properties of both tissues, namely the absorption, the scattering and the reduced scattering coefficients, as well as the scattering anisotropy, dispersion and light penetration depth, were calculated between 200 and 1000 nm. Analysis of the mean ab sorption coefficient spectra of the kidney tissues showed that both contain melanin and lipofuscin, and that 83 % of the melanin in the normal kidney converts into lipofuscin in the pathological kidney.
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spelling Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidneyHuman kidneyChromophobe renal cell carcinomaSpectral absorption coefficientMelaninLipofuscinRenal cancer discriminationA fast calculation method was used to obtain the spectral optical properties of human normal and pathological (chromophobe renal cell carcinoma) kidney tissues. Using total transmittance, total reflectance and collimated transmittance spectra acquired from ex vivo kidney samples, the spectral optical properties of both tissues, namely the absorption, the scattering and the reduced scattering coefficients, as well as the scattering anisotropy, dispersion and light penetration depth, were calculated between 200 and 1000 nm. Analysis of the mean ab sorption coefficient spectra of the kidney tissues showed that both contain melanin and lipofuscin, and that 83 % of the melanin in the normal kidney converts into lipofuscin in the pathological kidney.ElsevierRepositório Científico do Instituto Politécnico do PortoBotelho, Ana R.Silva, Hugo F.Martins, Inês S.Carneiro, IsaCarvalho, Sónia D.Henrique, Rui M.Tuchin, Valery V.Oliveira, Luís M.2023-03-17T17:27:29Z2023-02-052023-02-05T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/22542engBotelho, A. R., Silva, H. F., Martins, I. S., Carneiro, I. C., Carvalho, S. D., Henrique, R. M., Tuchin, V. V., & Oliveira, L. M. (2023). Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 286, 122002. https://doi.org/10.1016/j.saa.2022.1220021386-142510.1016/j.saa.2022.1220021873-3557info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-20T01:55:33Zoai:recipp.ipp.pt:10400.22/22542Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:45:02.616485Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney
title Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney
spellingShingle Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney
Botelho, Ana R.
Human kidney
Chromophobe renal cell carcinoma
Spectral absorption coefficient
Melanin
Lipofuscin
Renal cancer discrimination
title_short Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney
title_full Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney
title_fullStr Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney
title_full_unstemmed Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney
title_sort Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney
author Botelho, Ana R.
author_facet Botelho, Ana R.
Silva, Hugo F.
Martins, Inês S.
Carneiro, Isa
Carvalho, Sónia D.
Henrique, Rui M.
Tuchin, Valery V.
Oliveira, Luís M.
author_role author
author2 Silva, Hugo F.
Martins, Inês S.
Carneiro, Isa
Carvalho, Sónia D.
Henrique, Rui M.
Tuchin, Valery V.
Oliveira, Luís M.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Botelho, Ana R.
Silva, Hugo F.
Martins, Inês S.
Carneiro, Isa
Carvalho, Sónia D.
Henrique, Rui M.
Tuchin, Valery V.
Oliveira, Luís M.
dc.subject.por.fl_str_mv Human kidney
Chromophobe renal cell carcinoma
Spectral absorption coefficient
Melanin
Lipofuscin
Renal cancer discrimination
topic Human kidney
Chromophobe renal cell carcinoma
Spectral absorption coefficient
Melanin
Lipofuscin
Renal cancer discrimination
description A fast calculation method was used to obtain the spectral optical properties of human normal and pathological (chromophobe renal cell carcinoma) kidney tissues. Using total transmittance, total reflectance and collimated transmittance spectra acquired from ex vivo kidney samples, the spectral optical properties of both tissues, namely the absorption, the scattering and the reduced scattering coefficients, as well as the scattering anisotropy, dispersion and light penetration depth, were calculated between 200 and 1000 nm. Analysis of the mean ab sorption coefficient spectra of the kidney tissues showed that both contain melanin and lipofuscin, and that 83 % of the melanin in the normal kidney converts into lipofuscin in the pathological kidney.
publishDate 2023
dc.date.none.fl_str_mv 2023-03-17T17:27:29Z
2023-02-05
2023-02-05T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/22542
url http://hdl.handle.net/10400.22/22542
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Botelho, A. R., Silva, H. F., Martins, I. S., Carneiro, I. C., Carvalho, S. D., Henrique, R. M., Tuchin, V. V., & Oliveira, L. M. (2023). Fast calculation of spectral optical properties and pigment content detection in human normal and pathological kidney. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 286, 122002. https://doi.org/10.1016/j.saa.2022.122002
1386-1425
10.1016/j.saa.2022.122002
1873-3557
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799131535033499648

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