The risk factors for breast cancer: a case-control study.
Autor(a) principal: | |
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Data de Publicação: | 1993 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3072 |
Resumo: | In western countries, female breast cancer is a major cause of death. Many risk factors for breast cancer have been identified, but the magnitude of the risks is clearly different between high and low risk areas. In this hospital-based case-control study we evaluated risk factors for female breast cancer in 158 women with breast cancer and 131 controls. Cases presented a later age at first birth and a lower median number of pregnancies. The risk of breast cancer increased with increasing age at first birth, particularly for women with lower parity. After controlling for other variables the risk significantly decreased with abortion history (OR = 0.5, 95% CI: 0.3-0.7) and oral contraception (OR = 0.5, 95% CI: 0.3-0.9). Premenopausal and postmenopausal women presented different risk factors. Among premenopausal cases the risk was lower for parous women (OR = 0.1, 95% CI: 0.0-0.7) and higher for those with a positive family history (OR = 4.5, 95% CI: 1.3-16). Compared to controls, postmenopausal cases only presented a significantly lower rate of abortions (OR = 0.2, 95% CI: 0.1-0.4). The present study shows that these women can be regarded as belonging to an intermediate risk population. |
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The risk factors for breast cancer: a case-control study.Factores de risco para o cancro da mama: um estudo caso--controlo.In western countries, female breast cancer is a major cause of death. Many risk factors for breast cancer have been identified, but the magnitude of the risks is clearly different between high and low risk areas. In this hospital-based case-control study we evaluated risk factors for female breast cancer in 158 women with breast cancer and 131 controls. Cases presented a later age at first birth and a lower median number of pregnancies. The risk of breast cancer increased with increasing age at first birth, particularly for women with lower parity. After controlling for other variables the risk significantly decreased with abortion history (OR = 0.5, 95% CI: 0.3-0.7) and oral contraception (OR = 0.5, 95% CI: 0.3-0.9). Premenopausal and postmenopausal women presented different risk factors. Among premenopausal cases the risk was lower for parous women (OR = 0.1, 95% CI: 0.0-0.7) and higher for those with a positive family history (OR = 4.5, 95% CI: 1.3-16). Compared to controls, postmenopausal cases only presented a significantly lower rate of abortions (OR = 0.2, 95% CI: 0.1-0.4). The present study shows that these women can be regarded as belonging to an intermediate risk population.In western countries, female breast cancer is a major cause of death. Many risk factors for breast cancer have been identified, but the magnitude of the risks is clearly different between high and low risk areas. In this hospital-based case-control study we evaluated risk factors for female breast cancer in 158 women with breast cancer and 131 controls. Cases presented a later age at first birth and a lower median number of pregnancies. The risk of breast cancer increased with increasing age at first birth, particularly for women with lower parity. After controlling for other variables the risk significantly decreased with abortion history (OR = 0.5, 95% CI: 0.3-0.7) and oral contraception (OR = 0.5, 95% CI: 0.3-0.9). Premenopausal and postmenopausal women presented different risk factors. Among premenopausal cases the risk was lower for parous women (OR = 0.1, 95% CI: 0.0-0.7) and higher for those with a positive family history (OR = 4.5, 95% CI: 1.3-16). Compared to controls, postmenopausal cases only presented a significantly lower rate of abortions (OR = 0.2, 95% CI: 0.1-0.4). The present study shows that these women can be regarded as belonging to an intermediate risk population.Ordem dos Médicos1993-04-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3072oai:ojs.www.actamedicaportuguesa.com:article/3072Acta Médica Portuguesa; Vol. 6 No. 3-4 (1993): Março-Abril; 129-33Acta Médica Portuguesa; Vol. 6 N.º 3-4 (1993): Março-Abril; 129-331646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3072https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3072/2414Gandra, LBarros, HMoreira, ACalheiros, FMagalhães, Ninfo:eu-repo/semantics/openAccess2022-12-20T11:01:36Zoai:ojs.www.actamedicaportuguesa.com:article/3072Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:08.126741Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The risk factors for breast cancer: a case-control study. Factores de risco para o cancro da mama: um estudo caso--controlo. |
title |
The risk factors for breast cancer: a case-control study. |
spellingShingle |
The risk factors for breast cancer: a case-control study. Gandra, L |
title_short |
The risk factors for breast cancer: a case-control study. |
title_full |
The risk factors for breast cancer: a case-control study. |
title_fullStr |
The risk factors for breast cancer: a case-control study. |
title_full_unstemmed |
The risk factors for breast cancer: a case-control study. |
title_sort |
The risk factors for breast cancer: a case-control study. |
author |
Gandra, L |
author_facet |
Gandra, L Barros, H Moreira, A Calheiros, F Magalhães, N |
author_role |
author |
author2 |
Barros, H Moreira, A Calheiros, F Magalhães, N |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Gandra, L Barros, H Moreira, A Calheiros, F Magalhães, N |
description |
In western countries, female breast cancer is a major cause of death. Many risk factors for breast cancer have been identified, but the magnitude of the risks is clearly different between high and low risk areas. In this hospital-based case-control study we evaluated risk factors for female breast cancer in 158 women with breast cancer and 131 controls. Cases presented a later age at first birth and a lower median number of pregnancies. The risk of breast cancer increased with increasing age at first birth, particularly for women with lower parity. After controlling for other variables the risk significantly decreased with abortion history (OR = 0.5, 95% CI: 0.3-0.7) and oral contraception (OR = 0.5, 95% CI: 0.3-0.9). Premenopausal and postmenopausal women presented different risk factors. Among premenopausal cases the risk was lower for parous women (OR = 0.1, 95% CI: 0.0-0.7) and higher for those with a positive family history (OR = 4.5, 95% CI: 1.3-16). Compared to controls, postmenopausal cases only presented a significantly lower rate of abortions (OR = 0.2, 95% CI: 0.1-0.4). The present study shows that these women can be regarded as belonging to an intermediate risk population. |
publishDate |
1993 |
dc.date.none.fl_str_mv |
1993-04-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3072 oai:ojs.www.actamedicaportuguesa.com:article/3072 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3072 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/3072 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3072 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3072/2414 |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 6 No. 3-4 (1993): Março-Abril; 129-33 Acta Médica Portuguesa; Vol. 6 N.º 3-4 (1993): Março-Abril; 129-33 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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