Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination

Detalhes bibliográficos
Autor(a) principal: Brock, Jonas
Data de Publicação: 2020
Outros Autores: Lange, Martin, Guelbenzu‑Gonzalo, Maria, Meunier, Natascha, Vaz, Ana Margarida, Tratalos, Jamie A., Dittrich, Peter, Gunn, Michael, More, Simon J., Graham, David, Thulke, Hans‑Hermann
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.5/24130
Resumo: Research Areas: Veterinary Sciences
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spelling Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccinationInfectious Bovine Rhinotracheitis (IBR)Infection dynamicsIrelandSeasonal calvingSerosurveillanceDairyResearch Areas: Veterinary SciencesMany studies report age as a risk factor for BoHV-1 infection or seropositivity. However, it is unclear whether this pattern refects true epidemiological causation or is a consequence of study design and other issues. Here, we seek to understand the age-related dynamics of BoHV-1 seroprevalence in seasonal calving Irish dairy herds and provide decision support for the design and implementation of efective BoHV-1 testing strategies. We analysed seroprevalence data from dairy herds taken during two Irish seroprevalence surveys conducted between 2010 and 2017. Age-dependent seroprevalence profles were constructed for herds that were seropositive and unvaccinated. Some of these profles revealed a sudden increase in seroprevalence between adjacent age-cohorts, from absent or low to close to 100% of seropositive animals. By coupling the outcome of our data analysis with simulation output of an individual-based model at the herd scale, we have shown that these sudden increases are related to extensive virus circulation within a herd for a limited time, which may then subsequently remain latent over the following years. BoHV-1 outbreaks in dairy cattle herds afect animals independent of age and lead to almost 100% seroconversion in all age groups, or at least in all animals within a single epidemiological unit. In the absence of circulating infection, there is a year-on-year increase in the age-cohort at which seroprevalence changes from low to high. The fndings of this study inform recommendations regarding testing regimes in the context of contingency planning or an eradication programme in seasonal calving dairy herds.BMCRepositório da Universidade de LisboaBrock, JonasLange, MartinGuelbenzu‑Gonzalo, MariaMeunier, NataschaVaz, Ana MargaridaTratalos, Jamie A.Dittrich, PeterGunn, MichaelMore, Simon J.Graham, DavidThulke, Hans‑Hermann2022-04-20T21:38:07Z2020-09-252020-09-25T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/24130engBrock J, Lange M, Guelbenzu-Gonzalo M, Meunier N, Vaz AM, Tratalos JA, Dittrich P, Gunn M, More SJ, Graham D. 2020. Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination. Veterinary Research, 51(1):124. Doi 10.1186/s13567-020-00842-50928-424910.1186/s13567-020-00842-51297-9716info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-06T14:53:46Zoai:www.repository.utl.pt:10400.5/24130Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:08:14.804682Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination
title Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination
spellingShingle Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination
Brock, Jonas
Infectious Bovine Rhinotracheitis (IBR)
Infection dynamics
Ireland
Seasonal calving
Serosurveillance
Dairy
title_short Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination
title_full Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination
title_fullStr Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination
title_full_unstemmed Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination
title_sort Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination
author Brock, Jonas
author_facet Brock, Jonas
Lange, Martin
Guelbenzu‑Gonzalo, Maria
Meunier, Natascha
Vaz, Ana Margarida
Tratalos, Jamie A.
Dittrich, Peter
Gunn, Michael
More, Simon J.
Graham, David
Thulke, Hans‑Hermann
author_role author
author2 Lange, Martin
Guelbenzu‑Gonzalo, Maria
Meunier, Natascha
Vaz, Ana Margarida
Tratalos, Jamie A.
Dittrich, Peter
Gunn, Michael
More, Simon J.
Graham, David
Thulke, Hans‑Hermann
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Brock, Jonas
Lange, Martin
Guelbenzu‑Gonzalo, Maria
Meunier, Natascha
Vaz, Ana Margarida
Tratalos, Jamie A.
Dittrich, Peter
Gunn, Michael
More, Simon J.
Graham, David
Thulke, Hans‑Hermann
dc.subject.por.fl_str_mv Infectious Bovine Rhinotracheitis (IBR)
Infection dynamics
Ireland
Seasonal calving
Serosurveillance
Dairy
topic Infectious Bovine Rhinotracheitis (IBR)
Infection dynamics
Ireland
Seasonal calving
Serosurveillance
Dairy
description Research Areas: Veterinary Sciences
publishDate 2020
dc.date.none.fl_str_mv 2020-09-25
2020-09-25T00:00:00Z
2022-04-20T21:38:07Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/24130
url http://hdl.handle.net/10400.5/24130
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brock J, Lange M, Guelbenzu-Gonzalo M, Meunier N, Vaz AM, Tratalos JA, Dittrich P, Gunn M, More SJ, Graham D. 2020. Epidemiology of age-dependent prevalence of Bovine Herpes Virus Type 1 (BoHV-1) in dairy herds with and without vaccination. Veterinary Research, 51(1):124. Doi 10.1186/s13567-020-00842-5
0928-4249
10.1186/s13567-020-00842-5
1297-9716
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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