New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.8/8973 |
Resumo: | This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the Strategic Projects granted to MARE-Marine, Environmental Sciences Centre (UIDP/04292/2020 and UIDB/04292/2020), Associate Laboratory ARNET (LA/P/0069/2020), iMed.Ulisboa (UIDB/04138/2020 and UIDP/04138/2020), and Joana Marto (CEECINST/00145/2018). |
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New insights into the dermocosmetic potential of the red seaweed Gelidium corneumGelidium corneumGreener skincare productsMarine natural productsAntioxidant capacityPhotoprotectionWound healingTopical formulationsIn vivo compatibilityThis work was supported by the Portuguese Foundation for Science and Technology (FCT) through the Strategic Projects granted to MARE-Marine, Environmental Sciences Centre (UIDP/04292/2020 and UIDB/04292/2020), Associate Laboratory ARNET (LA/P/0069/2020), iMed.Ulisboa (UIDB/04138/2020 and UIDP/04138/2020), and Joana Marto (CEECINST/00145/2018).This work addresses the potential of the red seaweed Gelidium corneum as a source of bioactive ingredients for skin health and wellness in response to the growing awareness regarding the significance of sustainable strategies in developing new nature-based dermocosmetic products. Hydroalcoholic extracts from the dried biomass were subjected to sequential liquid–liquid partitions, affording five different fractions (F1–F5). Their cosmetic potential was assessed through a set of in vitro assays concerning their antioxidant, photoprotective, and healing properties. Additionally, their cytotoxicity in HaCaT cells and their capacity to induce inflammation in RAW 264.7 cells were also evaluated. As a proof-of-concept, O/W emulsions were prepared, and emulsion stability was assessed by optical microscopy, droplet size analysis, centrifugation tests, and rheology analysis. Furthermore, in vivo tests were conducted with the final formulation to assess its antioxidant capacity. At subtoxic concentrations, the most lipophilic fraction has provided photoprotection against UV light-induced photooxidation in HaCaT cells. This was conducted together with the aqueous fraction, which also displayed healing capacities. Regarding the physical and stability assays, the best performance was achieved with the formulation containing 1% aqueous extract, which exhibited water retention and antioxidant properties in the in vivo assay. In summary, Gelidium corneum displayed itself as a potential source of bioactive ingredients with multitarget properties for dermatological use.MDPIIC-OnlineMatias, MargaridaMartins, AliceAlves, CelsoSilva, JoanaPinteus, SuseteFitas, ManuelPinto, PedroMarto, JoanaRibeiro, HelenaMurray, PatrickPedrosa, Rui2023-11-29T10:45:02Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.8/8973engMatias, M.; Martins, A.; Alves, C.; Silva, J.; Pinteus, S.; Fitas, M.; Pinto, P.; Marto, J.; Ribeiro, H.; Murray, P.; et al. New Insights into the Dermocosmetic Potential of the Red Seaweed Gelidium corneum. Antioxidants 2023, 12, 1684. https:// doi.org/10.3390/antiox120916842076-392110.3390/antiox12091684info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-17T15:58:37Zoai:iconline.ipleiria.pt:10400.8/8973Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:51:34.485688Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum |
title |
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum |
spellingShingle |
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum Matias, Margarida Gelidium corneum Greener skincare products Marine natural products Antioxidant capacity Photoprotection Wound healing Topical formulations In vivo compatibility |
title_short |
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum |
title_full |
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum |
title_fullStr |
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum |
title_full_unstemmed |
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum |
title_sort |
New insights into the dermocosmetic potential of the red seaweed Gelidium corneum |
author |
Matias, Margarida |
author_facet |
Matias, Margarida Martins, Alice Alves, Celso Silva, Joana Pinteus, Susete Fitas, Manuel Pinto, Pedro Marto, Joana Ribeiro, Helena Murray, Patrick Pedrosa, Rui |
author_role |
author |
author2 |
Martins, Alice Alves, Celso Silva, Joana Pinteus, Susete Fitas, Manuel Pinto, Pedro Marto, Joana Ribeiro, Helena Murray, Patrick Pedrosa, Rui |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
IC-Online |
dc.contributor.author.fl_str_mv |
Matias, Margarida Martins, Alice Alves, Celso Silva, Joana Pinteus, Susete Fitas, Manuel Pinto, Pedro Marto, Joana Ribeiro, Helena Murray, Patrick Pedrosa, Rui |
dc.subject.por.fl_str_mv |
Gelidium corneum Greener skincare products Marine natural products Antioxidant capacity Photoprotection Wound healing Topical formulations In vivo compatibility |
topic |
Gelidium corneum Greener skincare products Marine natural products Antioxidant capacity Photoprotection Wound healing Topical formulations In vivo compatibility |
description |
This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the Strategic Projects granted to MARE-Marine, Environmental Sciences Centre (UIDP/04292/2020 and UIDB/04292/2020), Associate Laboratory ARNET (LA/P/0069/2020), iMed.Ulisboa (UIDB/04138/2020 and UIDP/04138/2020), and Joana Marto (CEECINST/00145/2018). |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-11-29T10:45:02Z 2023 2023-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.8/8973 |
url |
http://hdl.handle.net/10400.8/8973 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Matias, M.; Martins, A.; Alves, C.; Silva, J.; Pinteus, S.; Fitas, M.; Pinto, P.; Marto, J.; Ribeiro, H.; Murray, P.; et al. New Insights into the Dermocosmetic Potential of the Red Seaweed Gelidium corneum. Antioxidants 2023, 12, 1684. https:// doi.org/10.3390/antiox12091684 2076-3921 10.3390/antiox12091684 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799137007291596800 |