New insights into the dermocosmetic potential of the red seaweed Gelidium corneum

Detalhes bibliográficos
Autor(a) principal: Matias, Margarida
Data de Publicação: 2023
Outros Autores: Martins, Alice, Alves, Celso, Silva, Joana, Pinteus, Susete, Fitas, Manuel, Pinto, Pedro, Marto, Joana, Ribeiro, Helena, Murray, Patrick, Pedrosa, Rui
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.8/8973
Resumo: This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the Strategic Projects granted to MARE-Marine, Environmental Sciences Centre (UIDP/04292/2020 and UIDB/04292/2020), Associate Laboratory ARNET (LA/P/0069/2020), iMed.Ulisboa (UIDB/04138/2020 and UIDP/04138/2020), and Joana Marto (CEECINST/00145/2018).
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spelling New insights into the dermocosmetic potential of the red seaweed Gelidium corneumGelidium corneumGreener skincare productsMarine natural productsAntioxidant capacityPhotoprotectionWound healingTopical formulationsIn vivo compatibilityThis work was supported by the Portuguese Foundation for Science and Technology (FCT) through the Strategic Projects granted to MARE-Marine, Environmental Sciences Centre (UIDP/04292/2020 and UIDB/04292/2020), Associate Laboratory ARNET (LA/P/0069/2020), iMed.Ulisboa (UIDB/04138/2020 and UIDP/04138/2020), and Joana Marto (CEECINST/00145/2018).This work addresses the potential of the red seaweed Gelidium corneum as a source of bioactive ingredients for skin health and wellness in response to the growing awareness regarding the significance of sustainable strategies in developing new nature-based dermocosmetic products. Hydroalcoholic extracts from the dried biomass were subjected to sequential liquid–liquid partitions, affording five different fractions (F1–F5). Their cosmetic potential was assessed through a set of in vitro assays concerning their antioxidant, photoprotective, and healing properties. Additionally, their cytotoxicity in HaCaT cells and their capacity to induce inflammation in RAW 264.7 cells were also evaluated. As a proof-of-concept, O/W emulsions were prepared, and emulsion stability was assessed by optical microscopy, droplet size analysis, centrifugation tests, and rheology analysis. Furthermore, in vivo tests were conducted with the final formulation to assess its antioxidant capacity. At subtoxic concentrations, the most lipophilic fraction has provided photoprotection against UV light-induced photooxidation in HaCaT cells. This was conducted together with the aqueous fraction, which also displayed healing capacities. Regarding the physical and stability assays, the best performance was achieved with the formulation containing 1% aqueous extract, which exhibited water retention and antioxidant properties in the in vivo assay. In summary, Gelidium corneum displayed itself as a potential source of bioactive ingredients with multitarget properties for dermatological use.MDPIIC-OnlineMatias, MargaridaMartins, AliceAlves, CelsoSilva, JoanaPinteus, SuseteFitas, ManuelPinto, PedroMarto, JoanaRibeiro, HelenaMurray, PatrickPedrosa, Rui2023-11-29T10:45:02Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.8/8973engMatias, M.; Martins, A.; Alves, C.; Silva, J.; Pinteus, S.; Fitas, M.; Pinto, P.; Marto, J.; Ribeiro, H.; Murray, P.; et al. New Insights into the Dermocosmetic Potential of the Red Seaweed Gelidium corneum. Antioxidants 2023, 12, 1684. https:// doi.org/10.3390/antiox120916842076-392110.3390/antiox12091684info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-17T15:58:37Zoai:iconline.ipleiria.pt:10400.8/8973Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:51:34.485688Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
title New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
spellingShingle New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
Matias, Margarida
Gelidium corneum
Greener skincare products
Marine natural products
Antioxidant capacity
Photoprotection
Wound healing
Topical formulations
In vivo compatibility
title_short New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
title_full New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
title_fullStr New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
title_full_unstemmed New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
title_sort New insights into the dermocosmetic potential of the red seaweed Gelidium corneum
author Matias, Margarida
author_facet Matias, Margarida
Martins, Alice
Alves, Celso
Silva, Joana
Pinteus, Susete
Fitas, Manuel
Pinto, Pedro
Marto, Joana
Ribeiro, Helena
Murray, Patrick
Pedrosa, Rui
author_role author
author2 Martins, Alice
Alves, Celso
Silva, Joana
Pinteus, Susete
Fitas, Manuel
Pinto, Pedro
Marto, Joana
Ribeiro, Helena
Murray, Patrick
Pedrosa, Rui
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv IC-Online
dc.contributor.author.fl_str_mv Matias, Margarida
Martins, Alice
Alves, Celso
Silva, Joana
Pinteus, Susete
Fitas, Manuel
Pinto, Pedro
Marto, Joana
Ribeiro, Helena
Murray, Patrick
Pedrosa, Rui
dc.subject.por.fl_str_mv Gelidium corneum
Greener skincare products
Marine natural products
Antioxidant capacity
Photoprotection
Wound healing
Topical formulations
In vivo compatibility
topic Gelidium corneum
Greener skincare products
Marine natural products
Antioxidant capacity
Photoprotection
Wound healing
Topical formulations
In vivo compatibility
description This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the Strategic Projects granted to MARE-Marine, Environmental Sciences Centre (UIDP/04292/2020 and UIDB/04292/2020), Associate Laboratory ARNET (LA/P/0069/2020), iMed.Ulisboa (UIDB/04138/2020 and UIDP/04138/2020), and Joana Marto (CEECINST/00145/2018).
publishDate 2023
dc.date.none.fl_str_mv 2023-11-29T10:45:02Z
2023
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.8/8973
url http://hdl.handle.net/10400.8/8973
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Matias, M.; Martins, A.; Alves, C.; Silva, J.; Pinteus, S.; Fitas, M.; Pinto, P.; Marto, J.; Ribeiro, H.; Murray, P.; et al. New Insights into the Dermocosmetic Potential of the Red Seaweed Gelidium corneum. Antioxidants 2023, 12, 1684. https:// doi.org/10.3390/antiox12091684
2076-3921
10.3390/antiox12091684
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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