Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.48560/rspo.23306 |
Resumo: | Purpose:To compare the results between photorefractive keratectomy (PRK) with Custom-Q or with Wavefront-optimized (WFO) profiles in terms of asphericity and spherical aberrations, 6 months post-operative. Setting:Tertiary referral center (Centro Hospitalar e Universitário da Universidade de Coimbra, Coimbra, Portugal). Patients and Methods: Fifty-nine eyes (43 patients) were enrolled on this retrospective case series, including patients with myopia and/or astigmatism, submitted to refractive surgery with PRK (Allegretto WAVE Eye-Q Excimer Laser System, Alcon), in a Custom-Q ablation (38 eyes) or Wavefront-optimized procedure (21 eyes). We included patients with a minimum follow-up of 6 months; age over 21 years; stable refractive error for 2 years; spherical equivalent (SE) inferior to 5.50 diopters (D); percentage of altered tissue under 40% and expected final corneal curvature above 35 D. Eyes with other ophthalmological pathologies were excluded. Baseline and post-operative asphericity and optical aberrations were evaluated with Pentacam (Oculus Optikgeräte, Wetzlar, Germany). Results: The demographic and preoperative refractive data was similar between groups (all p≥0.05). Post-operative spherical equivalent in the Custom-Q and Wavefront-optimized groups was within 0.50D in 100% and 78.90% of eyes, respectively and within 0.25D in 97.06% and 73.70% of eyes, respectively. Variation of Q-value was 0.62±0.34. (range -0.07-1.24) for Custom Q group, and 0.65±0.39 (range -0.05-1.40) in the Wavefront-optimized group (p=0.82). In a multivariate linear regression model, variation of Q-value was not influenced by the ablation profile (B=0.04, p=0.49, 95%CI [-0.08,0.17]). SE was a strong predictor (B=-0.30, p<0.01, 95%CI[-0.39,-0.21]). There was a significant increase in RMS higher-order aberrations (p<0.01for both groups) and no difference between groups (p=0.53). Discussion and Conclusion: In our sample,Custom-Q ablation was not significantly different from Wavefront optimized ablation regarding post-operative asphericity. Although the increase in higher-order aberrations, both techniques were effective and safe for myopic and/or astigmatic correction up to -5.50D SE. |
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Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correctionQueratectomia Fotorrrefrativa Custom-Q versus Wavefront Optimized para Miopia com ou sem AstigmatismoArtigos OriginaisPurpose:To compare the results between photorefractive keratectomy (PRK) with Custom-Q or with Wavefront-optimized (WFO) profiles in terms of asphericity and spherical aberrations, 6 months post-operative. Setting:Tertiary referral center (Centro Hospitalar e Universitário da Universidade de Coimbra, Coimbra, Portugal). Patients and Methods: Fifty-nine eyes (43 patients) were enrolled on this retrospective case series, including patients with myopia and/or astigmatism, submitted to refractive surgery with PRK (Allegretto WAVE Eye-Q Excimer Laser System, Alcon), in a Custom-Q ablation (38 eyes) or Wavefront-optimized procedure (21 eyes). We included patients with a minimum follow-up of 6 months; age over 21 years; stable refractive error for 2 years; spherical equivalent (SE) inferior to 5.50 diopters (D); percentage of altered tissue under 40% and expected final corneal curvature above 35 D. Eyes with other ophthalmological pathologies were excluded. Baseline and post-operative asphericity and optical aberrations were evaluated with Pentacam (Oculus Optikgeräte, Wetzlar, Germany). Results: The demographic and preoperative refractive data was similar between groups (all p≥0.05). Post-operative spherical equivalent in the Custom-Q and Wavefront-optimized groups was within 0.50D in 100% and 78.90% of eyes, respectively and within 0.25D in 97.06% and 73.70% of eyes, respectively. Variation of Q-value was 0.62±0.34. (range -0.07-1.24) for Custom Q group, and 0.65±0.39 (range -0.05-1.40) in the Wavefront-optimized group (p=0.82). In a multivariate linear regression model, variation of Q-value was not influenced by the ablation profile (B=0.04, p=0.49, 95%CI [-0.08,0.17]). SE was a strong predictor (B=-0.30, p<0.01, 95%CI[-0.39,-0.21]). There was a significant increase in RMS higher-order aberrations (p<0.01for both groups) and no difference between groups (p=0.53). Discussion and Conclusion: In our sample,Custom-Q ablation was not significantly different from Wavefront optimized ablation regarding post-operative asphericity. Although the increase in higher-order aberrations, both techniques were effective and safe for myopic and/or astigmatic correction up to -5.50D SE.Objetivo:Comparar os resultados entre queratectomia fotorefrativa (PRK) com perfis Custom-Qou Wavefront-optimized(WFO) relativamente à asfericidade e aberrações esféricas, 6 meses após a cirurgia. Local:Centro de Referência Terciário (Centro Hospitalar e Universitário da Universidade de Coimbra, Coimbra, Portugal). Participantes e Métodos:Neste estudo retrospetivo foram incluídos 59 olhos (43 doentes) com miopia e/ou astigmatismo submetidos a cirurgia refrativa com PRK (Allegretto WAVE Eye-Q Excimer Laser System, Alcon). Trinta e oito olhos foram tratados com o procedimento Custom-Qe 21 olhos com o procedimento Wavefront-optimized. Foram incluídos doentes com um seguimento mínimo de 6 meses; idade acima de 21 anos; erro refrativo estável por 2 anos; equivalente esférico inferior a 5.50 dioptrias (D); percentagem de tecido alterado inferior a 40% e curvatura final da córnea esperada acima de 35 dioptrias. Foram excluídos olhos com outras patologias oftalmológicas. A asfericidade basal e pós-operatória e as aberrações ópticas foram avaliadas com Pentacam(Oculus Optikgeräte, Wetzlar, Germany). Resultados:Os dois grupos eram semelhantes quanto aos dados demográficos e dados refrativos pré-operatórios (p≥ 0.05). O equivalente esférico no pós-operatório foi inferior a 0.50D em 100% dos olhos no grupo Custom-Qe 78.90% dos olhos no grupo Wavefront-optimized, e foi inferior a 0.25D em 97.06% e 73.70% dos olhos, respetivamente. A variação do valor Q foi de 0.62±0.34 (intervalo -0.07-1.24) no grupo Custom-Qe 0.65±0.39 (intervalo -0.05-1.40) no grupo Wavefront-optimized(p=0.82). A variação do valor Q não foi influenciada pelo perfil de ablação (B=0.04, p=0.49, 95%CI [-0.08,0.17]) e o equivalente esférico foi um forte preditor (B=-0.30, p<0.01, 95%CI[-0.39,-0.21]). Verificou-se uma diferença significativa nas aberrações de alta ordem em cada grupo (p<0.01) apesar de não se ter observado uma diferença significativa entre os grupos (p=0.53). Discussão e conclusão: Na nossa amostra, a ablação com o perfilCustom-Qnão foi significativamente diferente do perfil Wavefront-optimizedrelativamente à asfericidade pós-operatória. Apesar do aumento nas aberrações de alta ordem, ambas as técnicas foram eficazes e seguras para a correção de miopia e/ou astigmatismo até -5.50D.Ajnet2021-09-29T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.48560/rspo.23306eng1646-69501646-6950Simão, Jorge MiguelOsório, InêsNeves, EmmanuelRaimundo, MiguelRosa, AndreiaQuadrado, Maria JoãoMurta, Joaquiminfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-22T17:06:14Zoai:ojs.revistas.rcaap.pt:article/23306Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:01:45.483168Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction Queratectomia Fotorrrefrativa Custom-Q versus Wavefront Optimized para Miopia com ou sem Astigmatismo |
title |
Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction |
spellingShingle |
Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction Simão, Jorge Miguel Artigos Originais |
title_short |
Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction |
title_full |
Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction |
title_fullStr |
Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction |
title_full_unstemmed |
Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction |
title_sort |
Custom-Q versus Wavefront Optimized Photorefractive Keratectomy for Myopia with or without Astigmatism correction |
author |
Simão, Jorge Miguel |
author_facet |
Simão, Jorge Miguel Osório, Inês Neves, Emmanuel Raimundo, Miguel Rosa, Andreia Quadrado, Maria João Murta, Joaquim |
author_role |
author |
author2 |
Osório, Inês Neves, Emmanuel Raimundo, Miguel Rosa, Andreia Quadrado, Maria João Murta, Joaquim |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Simão, Jorge Miguel Osório, Inês Neves, Emmanuel Raimundo, Miguel Rosa, Andreia Quadrado, Maria João Murta, Joaquim |
dc.subject.por.fl_str_mv |
Artigos Originais |
topic |
Artigos Originais |
description |
Purpose:To compare the results between photorefractive keratectomy (PRK) with Custom-Q or with Wavefront-optimized (WFO) profiles in terms of asphericity and spherical aberrations, 6 months post-operative. Setting:Tertiary referral center (Centro Hospitalar e Universitário da Universidade de Coimbra, Coimbra, Portugal). Patients and Methods: Fifty-nine eyes (43 patients) were enrolled on this retrospective case series, including patients with myopia and/or astigmatism, submitted to refractive surgery with PRK (Allegretto WAVE Eye-Q Excimer Laser System, Alcon), in a Custom-Q ablation (38 eyes) or Wavefront-optimized procedure (21 eyes). We included patients with a minimum follow-up of 6 months; age over 21 years; stable refractive error for 2 years; spherical equivalent (SE) inferior to 5.50 diopters (D); percentage of altered tissue under 40% and expected final corneal curvature above 35 D. Eyes with other ophthalmological pathologies were excluded. Baseline and post-operative asphericity and optical aberrations were evaluated with Pentacam (Oculus Optikgeräte, Wetzlar, Germany). Results: The demographic and preoperative refractive data was similar between groups (all p≥0.05). Post-operative spherical equivalent in the Custom-Q and Wavefront-optimized groups was within 0.50D in 100% and 78.90% of eyes, respectively and within 0.25D in 97.06% and 73.70% of eyes, respectively. Variation of Q-value was 0.62±0.34. (range -0.07-1.24) for Custom Q group, and 0.65±0.39 (range -0.05-1.40) in the Wavefront-optimized group (p=0.82). In a multivariate linear regression model, variation of Q-value was not influenced by the ablation profile (B=0.04, p=0.49, 95%CI [-0.08,0.17]). SE was a strong predictor (B=-0.30, p<0.01, 95%CI[-0.39,-0.21]). There was a significant increase in RMS higher-order aberrations (p<0.01for both groups) and no difference between groups (p=0.53). Discussion and Conclusion: In our sample,Custom-Q ablation was not significantly different from Wavefront optimized ablation regarding post-operative asphericity. Although the increase in higher-order aberrations, both techniques were effective and safe for myopic and/or astigmatic correction up to -5.50D SE. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-09-29T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.48560/rspo.23306 |
url |
https://doi.org/10.48560/rspo.23306 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1646-6950 1646-6950 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Ajnet |
publisher.none.fl_str_mv |
Ajnet |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799130482707791872 |