High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers

Detalhes bibliográficos
Autor(a) principal: Moura, Duarte Alexandre Campos Serra
Data de Publicação: 2016
Outros Autores: Caridade, S. G., Sousa, M. P., Cunha, E., Rocha, Helena, Mano, J. F., Paiva, M. C., Alves, N. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/43832
Resumo: In this work, novel free-standing (FS) films based on chitosan, alginate and graphene oxide (GO) were developed through layer-by-layer assembly. First, GO was synthesized from graphite and multi-walled carbon nanotubes using a modified Hummer's method, yielding oxidized graphene flakes (o-GFs) and oxidized graphene nanoribbons (o-GNRs), respectively, which were then characterized. Then FS films were produced and their morphological, thermal and mechanical properties, as well as the o-GF and o-GNR dispersion along the films were assessed. Their degradation and swelling profiles as well as their biological behavior were evaluated. Graphite and nanotubes were successfully oxidized and exfoliated forming stable suspensions that could be combined with chitosan (CHI) and alginate (ALG) solutions by layer-by-layer processing. The addition of o-GFs and o-GNRs resulted in rougher, hydrophilic FS films with significantly improved mechanical properties relative to CHI/ALG films. The presence of o-GFs or o-GNRs did not affect the thermal stability and the addition of o-GFs resulted in films with enhanced cytocompatibility. The results demonstrate the high potential of the GO reinforced films for biomedical applications, in particular o-GF films, for wound healing, and cardiac and bone engineering applications.
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spelling High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymersGrapheneHigh performance free-standing filmsLayer-by-layer assemblyNatural polymersScience & TechnologyIn this work, novel free-standing (FS) films based on chitosan, alginate and graphene oxide (GO) were developed through layer-by-layer assembly. First, GO was synthesized from graphite and multi-walled carbon nanotubes using a modified Hummer's method, yielding oxidized graphene flakes (o-GFs) and oxidized graphene nanoribbons (o-GNRs), respectively, which were then characterized. Then FS films were produced and their morphological, thermal and mechanical properties, as well as the o-GF and o-GNR dispersion along the films were assessed. Their degradation and swelling profiles as well as their biological behavior were evaluated. Graphite and nanotubes were successfully oxidized and exfoliated forming stable suspensions that could be combined with chitosan (CHI) and alginate (ALG) solutions by layer-by-layer processing. The addition of o-GFs and o-GNRs resulted in rougher, hydrophilic FS films with significantly improved mechanical properties relative to CHI/ALG films. The presence of o-GFs or o-GNRs did not affect the thermal stability and the addition of o-GFs resulted in films with enhanced cytocompatibility. The results demonstrate the high potential of the GO reinforced films for biomedical applications, in particular o-GF films, for wound healing, and cardiac and bone engineering applications.The authors acknowledge the Portuguese Foundation for Science and Technology (FCT) and the European program FEDER/ COMPETE for the financial support through project BioSeaGlue: EXPL/CTM-BIO/0646/2013 (FCOMP-01-0124-FEDER-041105) and for project PEst-C/CTM/LA0025/2013 (Strategic Project – LA 25 – 2013-2014). This work was also financially supported by FCT through the scholarships SFRH/BPD/96797/2013 granted to Sofia G. Caridade, SFRH/BD/97606/2013 granted to Maria Sousa, and SFRH/BD/87214/2012 granted to Eunice Cunha.Royal Society of ChemistryUniversidade do MinhoMoura, Duarte Alexandre Campos SerraCaridade, S. G.Sousa, M. P.Cunha, E.Rocha, HelenaMano, J. F.Paiva, M. C.Alves, N. M.2016-112016-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/43832engMoura D., Caridade S. G., Sousa M. P., Cunha E., Mano J. F., Paiva M. C., Alves N. M. High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers, Journal Of Materials Chemistry B, Vol. 4, Issue 47, pp. 7718-7730, doi:10.1039/C6TB02344D, 20162050-750X10.1039/C6TB02344Dhttp://dx.doi.org/10.1039/C6TB02344Dinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:22:17Zoai:repositorium.sdum.uminho.pt:1822/43832Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:15:44.946265Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers
title High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers
spellingShingle High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers
Moura, Duarte Alexandre Campos Serra
Graphene
High performance free-standing films
Layer-by-layer assembly
Natural polymers
Science & Technology
title_short High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers
title_full High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers
title_fullStr High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers
title_full_unstemmed High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers
title_sort High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers
author Moura, Duarte Alexandre Campos Serra
author_facet Moura, Duarte Alexandre Campos Serra
Caridade, S. G.
Sousa, M. P.
Cunha, E.
Rocha, Helena
Mano, J. F.
Paiva, M. C.
Alves, N. M.
author_role author
author2 Caridade, S. G.
Sousa, M. P.
Cunha, E.
Rocha, Helena
Mano, J. F.
Paiva, M. C.
Alves, N. M.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Moura, Duarte Alexandre Campos Serra
Caridade, S. G.
Sousa, M. P.
Cunha, E.
Rocha, Helena
Mano, J. F.
Paiva, M. C.
Alves, N. M.
dc.subject.por.fl_str_mv Graphene
High performance free-standing films
Layer-by-layer assembly
Natural polymers
Science & Technology
topic Graphene
High performance free-standing films
Layer-by-layer assembly
Natural polymers
Science & Technology
description In this work, novel free-standing (FS) films based on chitosan, alginate and graphene oxide (GO) were developed through layer-by-layer assembly. First, GO was synthesized from graphite and multi-walled carbon nanotubes using a modified Hummer's method, yielding oxidized graphene flakes (o-GFs) and oxidized graphene nanoribbons (o-GNRs), respectively, which were then characterized. Then FS films were produced and their morphological, thermal and mechanical properties, as well as the o-GF and o-GNR dispersion along the films were assessed. Their degradation and swelling profiles as well as their biological behavior were evaluated. Graphite and nanotubes were successfully oxidized and exfoliated forming stable suspensions that could be combined with chitosan (CHI) and alginate (ALG) solutions by layer-by-layer processing. The addition of o-GFs and o-GNRs resulted in rougher, hydrophilic FS films with significantly improved mechanical properties relative to CHI/ALG films. The presence of o-GFs or o-GNRs did not affect the thermal stability and the addition of o-GFs resulted in films with enhanced cytocompatibility. The results demonstrate the high potential of the GO reinforced films for biomedical applications, in particular o-GF films, for wound healing, and cardiac and bone engineering applications.
publishDate 2016
dc.date.none.fl_str_mv 2016-11
2016-11-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/43832
url http://hdl.handle.net/1822/43832
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Moura D., Caridade S. G., Sousa M. P., Cunha E., Mano J. F., Paiva M. C., Alves N. M. High performance free-standing films by layer-by-layer assembly of graphene flakes and ribbons with natural polymers, Journal Of Materials Chemistry B, Vol. 4, Issue 47, pp. 7718-7730, doi:10.1039/C6TB02344D, 2016
2050-750X
10.1039/C6TB02344D
http://dx.doi.org/10.1039/C6TB02344D
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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