Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation

Detalhes bibliográficos
Autor(a) principal: Rodrigues, Patrícia Monteiro
Data de Publicação: 2023
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/58964
Resumo: Tese de mestrado, Engenharia Biomédica e Biofísica, 2023, Universidade de Lisboa, Faculdade de Ciências
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spelling Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound NeuromodulationUltrassonsNeuromodulação UltrassónicaNão InvasivoRemoção de PulsoTeses de mestrado - 2023Departamento de FísicaTese de mestrado, Engenharia Biomédica e Biofísica, 2023, Universidade de Lisboa, Faculdade de CiênciasUltrasound neuromodulation is a promising ultrasound modality since it combines high spatial resolution and high coverage of the brain while remaining minimally invasive. It is performed by exciting a transducer with an alternating pulse signal at its resonance frequency. These pulse signals are typically sent in bursts. The piezoelectric transducer converts this signal into an acoustic wave, resulting in multiple acoustic waves within each burst. Bulk ceramic piezoelectric transducers have a high-quality factor, meaning that for a single pulse excitation, it produces several pulses with decaying amplitude. The main goal of this dissertation was to explore potential power savings in the ultrasound transmitter by removing pulses from a long burst of pulses and bursts from the neuromodulation cycle while minimizing the decay of the acoustic wave amplitude. This goal was accomplished by developing an experimental setup for ultrasound stimulation using two different transducers: High-Intensity Focused Ultrasound and Air-Backing transducers. In this study, it was also simulated two different approaches: removing pulses by short and open circuits. The results showed that using the Air-Backing transducer, it’s possible to save more energy than with the other transducer. The simulations from the Air-Backing transducer, in which only a percentage of the pulse amplitude was removed, showed better results than the total removal of the pulses, and among the results presented, the 30% amplitude removal is the case with the highest efficiency. Another comparison made in this project suggests that performing pulse removal through a short circuit generates very positive results while performing pulse removal through an open circuit was not beneficial to the hypothesis under study. Future work to be done should include experiments and simulations with neurons since the behavior of ultrasound in neurons is still not fully understood, and the obtained results may prove to be quite different from the simulations.Evans, Guiomar Gaspar de Andrade, 1966-Costa, Tiago Miguel Lopes Marta daRepositório da Universidade de LisboaRodrigues, Patrícia Monteiro2023-08-23T10:14:32Z202320232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10451/58964enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:07:56Zoai:repositorio.ul.pt:10451/58964Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:09:01.733126Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation
title Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation
spellingShingle Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation
Rodrigues, Patrícia Monteiro
Ultrassons
Neuromodulação Ultrassónica
Não Invasivo
Remoção de Pulso
Teses de mestrado - 2023
Departamento de Física
title_short Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation
title_full Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation
title_fullStr Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation
title_full_unstemmed Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation
title_sort Ultrasound Waveform Optimization for Power Efficient Focused Ultrasound Neuromodulation
author Rodrigues, Patrícia Monteiro
author_facet Rodrigues, Patrícia Monteiro
author_role author
dc.contributor.none.fl_str_mv Evans, Guiomar Gaspar de Andrade, 1966-
Costa, Tiago Miguel Lopes Marta da
Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Rodrigues, Patrícia Monteiro
dc.subject.por.fl_str_mv Ultrassons
Neuromodulação Ultrassónica
Não Invasivo
Remoção de Pulso
Teses de mestrado - 2023
Departamento de Física
topic Ultrassons
Neuromodulação Ultrassónica
Não Invasivo
Remoção de Pulso
Teses de mestrado - 2023
Departamento de Física
description Tese de mestrado, Engenharia Biomédica e Biofísica, 2023, Universidade de Lisboa, Faculdade de Ciências
publishDate 2023
dc.date.none.fl_str_mv 2023-08-23T10:14:32Z
2023
2023
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/58964
url http://hdl.handle.net/10451/58964
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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