Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis

Detalhes bibliográficos
Autor(a) principal: Dinis-Ferreira, Sofia
Data de Publicação: 2020
Outros Autores: Lemos, Cláudia, Caldeira, Mónica, Homem-Costa, Miguel, Brazão, Maria da Luz, Aveiro, Fernando
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/33001
Resumo: Isolated congenital asplenia is a rare condition that mostly manifests in the early years, usually due to fatal systemic infections. In this paper, however, we present a case of a 36-year-old asymptomatic patient who was referred for suspected hyposplenism, with no history of splenectomy. There were no significant changes on physical examination. Blood analysis revealed leukocytosis and thrombocytosis as well as moderate anisopoikilocytosis and red blood cells with Howell-Jolly bodies. No spleen or other malformations were identified on imaging. Individuals with isolated congenital asplenia have an increased susceptibility to invasive infections and sepsis, with rapid clinical decline and a high mortality rate despite treatment.
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spelling Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare DiagnosisIsolated congenital asplenia,Madeira IslandhyposplenismsepsisPortugalIsolated congenital asplenia is a rare condition that mostly manifests in the early years, usually due to fatal systemic infections. In this paper, however, we present a case of a 36-year-old asymptomatic patient who was referred for suspected hyposplenism, with no history of splenectomy. There were no significant changes on physical examination. Blood analysis revealed leukocytosis and thrombocytosis as well as moderate anisopoikilocytosis and red blood cells with Howell-Jolly bodies. No spleen or other malformations were identified on imaging. Individuals with isolated congenital asplenia have an increased susceptibility to invasive infections and sepsis, with rapid clinical decline and a high mortality rate despite treatment.Repositório ComumDinis-Ferreira, SofiaLemos, CláudiaCaldeira, MónicaHomem-Costa, MiguelBrazão, Maria da LuzAveiro, Fernando2020-07-27T16:22:22Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/33001engDinis-Ferreira S, Lemos C, Caldeira M, Homem-Costa M, da Luz Brazão M, Aveiro F. Isolated congenital asplenia in an asymptomatic10.12890/2020_001429info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T02:16:48Zoai:comum.rcaap.pt:10400.26/33001Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:34:27.167448Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis
title Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis
spellingShingle Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis
Dinis-Ferreira, Sofia
Isolated congenital asplenia,
Madeira Island
hyposplenism
sepsis
Portugal
title_short Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis
title_full Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis
title_fullStr Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis
title_full_unstemmed Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis
title_sort Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis
author Dinis-Ferreira, Sofia
author_facet Dinis-Ferreira, Sofia
Lemos, Cláudia
Caldeira, Mónica
Homem-Costa, Miguel
Brazão, Maria da Luz
Aveiro, Fernando
author_role author
author2 Lemos, Cláudia
Caldeira, Mónica
Homem-Costa, Miguel
Brazão, Maria da Luz
Aveiro, Fernando
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Dinis-Ferreira, Sofia
Lemos, Cláudia
Caldeira, Mónica
Homem-Costa, Miguel
Brazão, Maria da Luz
Aveiro, Fernando
dc.subject.por.fl_str_mv Isolated congenital asplenia,
Madeira Island
hyposplenism
sepsis
Portugal
topic Isolated congenital asplenia,
Madeira Island
hyposplenism
sepsis
Portugal
description Isolated congenital asplenia is a rare condition that mostly manifests in the early years, usually due to fatal systemic infections. In this paper, however, we present a case of a 36-year-old asymptomatic patient who was referred for suspected hyposplenism, with no history of splenectomy. There were no significant changes on physical examination. Blood analysis revealed leukocytosis and thrombocytosis as well as moderate anisopoikilocytosis and red blood cells with Howell-Jolly bodies. No spleen or other malformations were identified on imaging. Individuals with isolated congenital asplenia have an increased susceptibility to invasive infections and sepsis, with rapid clinical decline and a high mortality rate despite treatment.
publishDate 2020
dc.date.none.fl_str_mv 2020-07-27T16:22:22Z
2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/33001
url http://hdl.handle.net/10400.26/33001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Dinis-Ferreira S, Lemos C, Caldeira M, Homem-Costa M, da Luz Brazão M, Aveiro F. Isolated congenital asplenia in an asymptomatic
10.12890/2020_001429
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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