Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications

Detalhes bibliográficos
Autor(a) principal: Navarro-Sempere, Alicia
Data de Publicação: 2021
Outros Autores: García, Magdalena, Rodrigues, Armindo, Garcia, Patrícia, Camarinho, Ricardo, Segovia, Yolanda
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10045/117285
Resumo: Mercury accumulation has been proposed as a toxic factor that causes neurodegenerative diseases. However, the hazardous health effects of gaseous elemental mercury exposure on the spinal cord in volcanic areas have not been reported previously in the literature. To evaluate the presence of volcanogenic inorganic mercury in the spinal cord, a study was carried out in São Miguel island (Azores, Portugal) by comparing the spinal cord of mice exposed chronically to an active volcanic environment (Furnas village) with individuals not exposed (Rabo de Peixe village), through the autometallographic silver enhancement histochemical method. Moreover, a morphometric and quantification analysis of the axons was carried out. Results exhibited mercury deposits at the lumbar level of the spinal cord in the specimens captured at the site with volcanic activity (Furnas village). A decrease in axon calibre and axonal atrophy was also observed in these specimens. Given that these are relevant hallmarks in the neurodegenerative pathologies, our results highlight the importance of the surveillance of the health of populations chronically exposed to active volcanic environments.
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spelling Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health ImplicationsAutometallographyEnvironmental PollutantsHeavy MetalsNeurotoxicityMotor NeuronsAxonsMotor Neuron DiseasesMus musculusMercury accumulation has been proposed as a toxic factor that causes neurodegenerative diseases. However, the hazardous health effects of gaseous elemental mercury exposure on the spinal cord in volcanic areas have not been reported previously in the literature. To evaluate the presence of volcanogenic inorganic mercury in the spinal cord, a study was carried out in São Miguel island (Azores, Portugal) by comparing the spinal cord of mice exposed chronically to an active volcanic environment (Furnas village) with individuals not exposed (Rabo de Peixe village), through the autometallographic silver enhancement histochemical method. Moreover, a morphometric and quantification analysis of the axons was carried out. Results exhibited mercury deposits at the lumbar level of the spinal cord in the specimens captured at the site with volcanic activity (Furnas village). A decrease in axon calibre and axonal atrophy was also observed in these specimens. Given that these are relevant hallmarks in the neurodegenerative pathologies, our results highlight the importance of the surveillance of the health of populations chronically exposed to active volcanic environments.This research was supported by the University of Alicante VIGROB-186.SpringerRepositório da Universidade dos AçoresNavarro-Sempere, AliciaGarcía, MagdalenaRodrigues, ArmindoGarcia, PatríciaCamarinho, RicardoSegovia, Yolanda2022-11-21T17:37:23Z2021-082021-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10045/117285engNavarro-Sempere, A., Garcia, M., Rodrigues, A., Garcia, P.V., Camarinho, R. & Segovia Y. (2022). Occurrence of volcanogenic inorganic mercury in wild mice spinal cord: potential health implications. "Biological Trace Elements Research", 200(6), 2838-2847. DOI:10.1007/s12011-021-02890-00163-498410.1007/s12011-021-02890-01559-0720PMC913284334415497000686876200002info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-12-20T14:34:55Zoai:repositorio.uac.pt:10400.3/6435Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:28:32.954323Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications
title Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications
spellingShingle Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications
Navarro-Sempere, Alicia
Autometallography
Environmental Pollutants
Heavy Metals
Neurotoxicity
Motor Neurons
Axons
Motor Neuron Diseases
Mus musculus
title_short Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications
title_full Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications
title_fullStr Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications
title_full_unstemmed Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications
title_sort Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications
author Navarro-Sempere, Alicia
author_facet Navarro-Sempere, Alicia
García, Magdalena
Rodrigues, Armindo
Garcia, Patrícia
Camarinho, Ricardo
Segovia, Yolanda
author_role author
author2 García, Magdalena
Rodrigues, Armindo
Garcia, Patrícia
Camarinho, Ricardo
Segovia, Yolanda
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade dos Açores
dc.contributor.author.fl_str_mv Navarro-Sempere, Alicia
García, Magdalena
Rodrigues, Armindo
Garcia, Patrícia
Camarinho, Ricardo
Segovia, Yolanda
dc.subject.por.fl_str_mv Autometallography
Environmental Pollutants
Heavy Metals
Neurotoxicity
Motor Neurons
Axons
Motor Neuron Diseases
Mus musculus
topic Autometallography
Environmental Pollutants
Heavy Metals
Neurotoxicity
Motor Neurons
Axons
Motor Neuron Diseases
Mus musculus
description Mercury accumulation has been proposed as a toxic factor that causes neurodegenerative diseases. However, the hazardous health effects of gaseous elemental mercury exposure on the spinal cord in volcanic areas have not been reported previously in the literature. To evaluate the presence of volcanogenic inorganic mercury in the spinal cord, a study was carried out in São Miguel island (Azores, Portugal) by comparing the spinal cord of mice exposed chronically to an active volcanic environment (Furnas village) with individuals not exposed (Rabo de Peixe village), through the autometallographic silver enhancement histochemical method. Moreover, a morphometric and quantification analysis of the axons was carried out. Results exhibited mercury deposits at the lumbar level of the spinal cord in the specimens captured at the site with volcanic activity (Furnas village). A decrease in axon calibre and axonal atrophy was also observed in these specimens. Given that these are relevant hallmarks in the neurodegenerative pathologies, our results highlight the importance of the surveillance of the health of populations chronically exposed to active volcanic environments.
publishDate 2021
dc.date.none.fl_str_mv 2021-08
2021-08-01T00:00:00Z
2022-11-21T17:37:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10045/117285
url http://hdl.handle.net/10045/117285
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Navarro-Sempere, A., Garcia, M., Rodrigues, A., Garcia, P.V., Camarinho, R. & Segovia Y. (2022). Occurrence of volcanogenic inorganic mercury in wild mice spinal cord: potential health implications. "Biological Trace Elements Research", 200(6), 2838-2847. DOI:10.1007/s12011-021-02890-0
0163-4984
10.1007/s12011-021-02890-0
1559-0720
PMC9132843
34415497
000686876200002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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