Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/107384 https://doi.org/10.1038/s41598-019-55838-9 |
Resumo: | Chemical contamination may cause genetic erosion in natural populations by wiping out the most sensitive genotypes. This is of upmost concern if the loss of genetic variability is irreversible due to contaminant-driven elimination of alleles, which may happen if tolerance is a recessive or incompletely dominant trait - the recessive tolerance inheritance (working-) hypothesis. Accordingly, this work investigated the tolerance inheritance to lethal levels of a metal-rich acid mine drainage (AMD) and to copper sulphate in a population of Pelophylax perezi. Time-to-death for each egg, after being exposed to 60% of a sample of acid mine drainage and to 9 mg/L Cu, was registered, and, for each egg mass, the median lethal time (LT50) and respective quartiles (LT25 and LT75) were computed. Results suggested that genetically determined tolerance could be probably driven by incomplete dominance (with possible maternal effect influence), preliminarily supporting the initial hypothesis. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Genetically inherited tolerance may unveil trait dominance patterns in an amphibian modelAcidsAdaptation, PhysiologicalAnimalsBiological AssayCopperInheritance PatternsMiningModels, AnimalRanidaeQuantitative Trait, HeritableChemical contamination may cause genetic erosion in natural populations by wiping out the most sensitive genotypes. This is of upmost concern if the loss of genetic variability is irreversible due to contaminant-driven elimination of alleles, which may happen if tolerance is a recessive or incompletely dominant trait - the recessive tolerance inheritance (working-) hypothesis. Accordingly, this work investigated the tolerance inheritance to lethal levels of a metal-rich acid mine drainage (AMD) and to copper sulphate in a population of Pelophylax perezi. Time-to-death for each egg, after being exposed to 60% of a sample of acid mine drainage and to 9 mg/L Cu, was registered, and, for each egg mass, the median lethal time (LT50) and respective quartiles (LT25 and LT75) were computed. Results suggested that genetically determined tolerance could be probably driven by incomplete dominance (with possible maternal effect influence), preliminarily supporting the initial hypothesis.Springer Nature2019-12-16info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/107384http://hdl.handle.net/10316/107384https://doi.org/10.1038/s41598-019-55838-9eng2045-2322Fasola, E.Ribeiro, R.Lopes, I.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-07T08:12:34Zoai:estudogeral.uc.pt:10316/107384Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:23:44.797612Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model |
title |
Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model |
spellingShingle |
Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model Fasola, E. Acids Adaptation, Physiological Animals Biological Assay Copper Inheritance Patterns Mining Models, Animal Ranidae Quantitative Trait, Heritable |
title_short |
Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model |
title_full |
Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model |
title_fullStr |
Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model |
title_full_unstemmed |
Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model |
title_sort |
Genetically inherited tolerance may unveil trait dominance patterns in an amphibian model |
author |
Fasola, E. |
author_facet |
Fasola, E. Ribeiro, R. Lopes, I. |
author_role |
author |
author2 |
Ribeiro, R. Lopes, I. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Fasola, E. Ribeiro, R. Lopes, I. |
dc.subject.por.fl_str_mv |
Acids Adaptation, Physiological Animals Biological Assay Copper Inheritance Patterns Mining Models, Animal Ranidae Quantitative Trait, Heritable |
topic |
Acids Adaptation, Physiological Animals Biological Assay Copper Inheritance Patterns Mining Models, Animal Ranidae Quantitative Trait, Heritable |
description |
Chemical contamination may cause genetic erosion in natural populations by wiping out the most sensitive genotypes. This is of upmost concern if the loss of genetic variability is irreversible due to contaminant-driven elimination of alleles, which may happen if tolerance is a recessive or incompletely dominant trait - the recessive tolerance inheritance (working-) hypothesis. Accordingly, this work investigated the tolerance inheritance to lethal levels of a metal-rich acid mine drainage (AMD) and to copper sulphate in a population of Pelophylax perezi. Time-to-death for each egg, after being exposed to 60% of a sample of acid mine drainage and to 9 mg/L Cu, was registered, and, for each egg mass, the median lethal time (LT50) and respective quartiles (LT25 and LT75) were computed. Results suggested that genetically determined tolerance could be probably driven by incomplete dominance (with possible maternal effect influence), preliminarily supporting the initial hypothesis. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-12-16 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/107384 http://hdl.handle.net/10316/107384 https://doi.org/10.1038/s41598-019-55838-9 |
url |
http://hdl.handle.net/10316/107384 https://doi.org/10.1038/s41598-019-55838-9 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2045-2322 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Springer Nature |
publisher.none.fl_str_mv |
Springer Nature |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799134123815600128 |