General practitioners’ deprescribing decisions in older adults with polypharmacy

Detalhes bibliográficos
Autor(a) principal: Jungo, Katharina Tabea
Data de Publicação: 2021
Outros Autores: Mantelli, Sophie, Rozsnyai, Zsofia, Missiou, Aristea, Kitanovska, Biljana Gerasimovska, Weltermann, Birgitta, Mallen, Christian, Collins, Claire, Bonfim, Daiana, Kurpas, Donata, Petrazzuoli, Ferdinando, Dumitra, Gindrovel, Thulesius, Hans, Lingner, Heidrun, Johansen, Kasper Lorenz, Wallis, Katharine, Hoffmann, Kathryn, Peremans, Lieve, Pilv, Liina, Šter, Marija Petek, Bleckwenn, Markus, Sattler, Martin, van der Ploeg, Milly, Torzsa, Péter, Kánská, Petra Bomberová, Vinker, Shlomo, Assenova, Radost, Bravo, Raquel Gomez, Viegas, Rita P.A., Tsopra, Rosy, Pestic, Sanda Kreitmayer, Gintere, Sandra, Koskela, Tuomas H., Lazic, Vanja, Tkachenko, Victoria, Reeve, Emily, Luymes, Clare, Poortvliet, Rosalinde K.E., Rodondi, Nicolas, Gussekloo, Jacobijn, Streit, Sven
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/110137
Resumo: Funding: The work of Katharina Tabea Jungo was supported by the Swiss National Science Foundation (SNSF) (NFP 407440_167465, PI Prof. Streit) and the work of Zsofia Rozsnyai by the Swiss Society of General Internal Medicine (SGAIM) Foundation (PI Prof. Streit). The SGAIM Foundation reviewed the study protocol but did not give us feedback or help usplan, conduct, interpret results, or write this manuscript. The SNSF had the same role but did not review the study protocol. CM is funded by the National Institute for Health Research (NIHR) Applied Research Collaborations (West Midlands), the NIHR School for Primary Caren Research and an NIHR Research Professorship in General Practice (RP 2014–04-026). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. ER is supported by an NHMRC-ARC Dementia Research Development Fellowship.
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spelling General practitioners’ deprescribing decisions in older adults with polypharmacya case vignette study in 31 countriesDeprescribingMultimorbidityOld agePolypharmacyPrimary health careGeriatrics and GerontologySDG 3 - Good Health and Well-beingFunding: The work of Katharina Tabea Jungo was supported by the Swiss National Science Foundation (SNSF) (NFP 407440_167465, PI Prof. Streit) and the work of Zsofia Rozsnyai by the Swiss Society of General Internal Medicine (SGAIM) Foundation (PI Prof. Streit). The SGAIM Foundation reviewed the study protocol but did not give us feedback or help usplan, conduct, interpret results, or write this manuscript. The SNSF had the same role but did not review the study protocol. CM is funded by the National Institute for Health Research (NIHR) Applied Research Collaborations (West Midlands), the NIHR School for Primary Caren Research and an NIHR Research Professorship in General Practice (RP 2014–04-026). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. ER is supported by an NHMRC-ARC Dementia Research Development Fellowship.Background: General practitioners (GPs) should regularly review patients’ medications and, if necessary, deprescribe, as inappropriate polypharmacy may harm patients’ health. However, deprescribing can be challenging for physicians. This study investigates GPs’ deprescribing decisions in 31 countries. Methods: In this case vignette study, GPs were invited to participate in an online survey containing three clinical cases of oldest-old multimorbid patients with potentially inappropriate polypharmacy. Patients differed in terms of dependency in activities of daily living (ADL) and were presented with and without history of cardiovascular disease (CVD). For each case, we asked GPs if they would deprescribe in their usual practice. We calculated proportions of GPs who reported they would deprescribe and performed a multilevel logistic regression to examine the association between history of CVD and level of dependency on GPs’ deprescribing decisions. Results: Of 3,175 invited GPs, 54% responded (N = 1,706). The mean age was 50 years and 60% of respondents were female. Despite differences across GP characteristics, such as age (with older GPs being more likely to take deprescribing decisions), and across countries, overall more than 80% of GPs reported they would deprescribe the dosage of at least one medication in oldest-old patients (> 80 years) with polypharmacy irrespective of history of CVD. The odds of deprescribing was higher in patients with a higher level of dependency in ADL (OR =1.5, 95%CI 1.25 to 1.80) and absence of CVD (OR =3.04, 95%CI 2.58 to 3.57). Interpretation: The majority of GPs in this study were willing to deprescribe one or more medications in oldest-old multimorbid patients with polypharmacy. Willingness was higher in patients with increased dependency in ADL and lower in patients with CVD.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNJungo, Katharina TabeaMantelli, SophieRozsnyai, ZsofiaMissiou, AristeaKitanovska, Biljana GerasimovskaWeltermann, BirgittaMallen, ChristianCollins, ClaireBonfim, DaianaKurpas, DonataPetrazzuoli, FerdinandoDumitra, GindrovelThulesius, HansLingner, HeidrunJohansen, Kasper LorenzWallis, KatharineHoffmann, KathrynPeremans, LievePilv, LiinaŠter, Marija PetekBleckwenn, MarkusSattler, Martinvan der Ploeg, MillyTorzsa, PéterKánská, Petra BomberováVinker, ShlomoAssenova, RadostBravo, Raquel GomezViegas, Rita P.A.Tsopra, RosyPestic, Sanda KreitmayerGintere, SandraKoskela, Tuomas H.Lazic, VanjaTkachenko, VictoriaReeve, EmilyLuymes, ClarePoortvliet, Rosalinde K.E.Rodondi, NicolasGussekloo, JacobijnStreit, Sven2021-01-12T23:24:07Z2021-01-072021-01-07T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/110137eng1471-2318PURE: 27460121https://doi.org/10.1186/s12877-020-01953-6info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:54:10Zoai:run.unl.pt:10362/110137Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:41:34.812264Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv General practitioners’ deprescribing decisions in older adults with polypharmacy
a case vignette study in 31 countries
title General practitioners’ deprescribing decisions in older adults with polypharmacy
spellingShingle General practitioners’ deprescribing decisions in older adults with polypharmacy
Jungo, Katharina Tabea
Deprescribing
Multimorbidity
Old age
Polypharmacy
Primary health care
Geriatrics and Gerontology
SDG 3 - Good Health and Well-being
title_short General practitioners’ deprescribing decisions in older adults with polypharmacy
title_full General practitioners’ deprescribing decisions in older adults with polypharmacy
title_fullStr General practitioners’ deprescribing decisions in older adults with polypharmacy
title_full_unstemmed General practitioners’ deprescribing decisions in older adults with polypharmacy
title_sort General practitioners’ deprescribing decisions in older adults with polypharmacy
author Jungo, Katharina Tabea
author_facet Jungo, Katharina Tabea
Mantelli, Sophie
Rozsnyai, Zsofia
Missiou, Aristea
Kitanovska, Biljana Gerasimovska
Weltermann, Birgitta
Mallen, Christian
Collins, Claire
Bonfim, Daiana
Kurpas, Donata
Petrazzuoli, Ferdinando
Dumitra, Gindrovel
Thulesius, Hans
Lingner, Heidrun
Johansen, Kasper Lorenz
Wallis, Katharine
Hoffmann, Kathryn
Peremans, Lieve
Pilv, Liina
Šter, Marija Petek
Bleckwenn, Markus
Sattler, Martin
van der Ploeg, Milly
Torzsa, Péter
Kánská, Petra Bomberová
Vinker, Shlomo
Assenova, Radost
Bravo, Raquel Gomez
Viegas, Rita P.A.
Tsopra, Rosy
Pestic, Sanda Kreitmayer
Gintere, Sandra
Koskela, Tuomas H.
Lazic, Vanja
Tkachenko, Victoria
Reeve, Emily
Luymes, Clare
Poortvliet, Rosalinde K.E.
Rodondi, Nicolas
Gussekloo, Jacobijn
Streit, Sven
author_role author
author2 Mantelli, Sophie
Rozsnyai, Zsofia
Missiou, Aristea
Kitanovska, Biljana Gerasimovska
Weltermann, Birgitta
Mallen, Christian
Collins, Claire
Bonfim, Daiana
Kurpas, Donata
Petrazzuoli, Ferdinando
Dumitra, Gindrovel
Thulesius, Hans
Lingner, Heidrun
Johansen, Kasper Lorenz
Wallis, Katharine
Hoffmann, Kathryn
Peremans, Lieve
Pilv, Liina
Šter, Marija Petek
Bleckwenn, Markus
Sattler, Martin
van der Ploeg, Milly
Torzsa, Péter
Kánská, Petra Bomberová
Vinker, Shlomo
Assenova, Radost
Bravo, Raquel Gomez
Viegas, Rita P.A.
Tsopra, Rosy
Pestic, Sanda Kreitmayer
Gintere, Sandra
Koskela, Tuomas H.
Lazic, Vanja
Tkachenko, Victoria
Reeve, Emily
Luymes, Clare
Poortvliet, Rosalinde K.E.
Rodondi, Nicolas
Gussekloo, Jacobijn
Streit, Sven
author2_role author
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author
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dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Jungo, Katharina Tabea
Mantelli, Sophie
Rozsnyai, Zsofia
Missiou, Aristea
Kitanovska, Biljana Gerasimovska
Weltermann, Birgitta
Mallen, Christian
Collins, Claire
Bonfim, Daiana
Kurpas, Donata
Petrazzuoli, Ferdinando
Dumitra, Gindrovel
Thulesius, Hans
Lingner, Heidrun
Johansen, Kasper Lorenz
Wallis, Katharine
Hoffmann, Kathryn
Peremans, Lieve
Pilv, Liina
Šter, Marija Petek
Bleckwenn, Markus
Sattler, Martin
van der Ploeg, Milly
Torzsa, Péter
Kánská, Petra Bomberová
Vinker, Shlomo
Assenova, Radost
Bravo, Raquel Gomez
Viegas, Rita P.A.
Tsopra, Rosy
Pestic, Sanda Kreitmayer
Gintere, Sandra
Koskela, Tuomas H.
Lazic, Vanja
Tkachenko, Victoria
Reeve, Emily
Luymes, Clare
Poortvliet, Rosalinde K.E.
Rodondi, Nicolas
Gussekloo, Jacobijn
Streit, Sven
dc.subject.por.fl_str_mv Deprescribing
Multimorbidity
Old age
Polypharmacy
Primary health care
Geriatrics and Gerontology
SDG 3 - Good Health and Well-being
topic Deprescribing
Multimorbidity
Old age
Polypharmacy
Primary health care
Geriatrics and Gerontology
SDG 3 - Good Health and Well-being
description Funding: The work of Katharina Tabea Jungo was supported by the Swiss National Science Foundation (SNSF) (NFP 407440_167465, PI Prof. Streit) and the work of Zsofia Rozsnyai by the Swiss Society of General Internal Medicine (SGAIM) Foundation (PI Prof. Streit). The SGAIM Foundation reviewed the study protocol but did not give us feedback or help usplan, conduct, interpret results, or write this manuscript. The SNSF had the same role but did not review the study protocol. CM is funded by the National Institute for Health Research (NIHR) Applied Research Collaborations (West Midlands), the NIHR School for Primary Caren Research and an NIHR Research Professorship in General Practice (RP 2014–04-026). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. ER is supported by an NHMRC-ARC Dementia Research Development Fellowship.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-12T23:24:07Z
2021-01-07
2021-01-07T00:00:00Z
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url http://hdl.handle.net/10362/110137
dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 1471-2318
PURE: 27460121
https://doi.org/10.1186/s12877-020-01953-6
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