Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides

Detalhes bibliográficos
Autor(a) principal: Antunes, Filipe E.
Data de Publicação: 2008
Outros Autores: Coppola, Luigi, Rossi, Cesare Oliviero, Ranieri, Giuseppe Antonio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/3769
https://doi.org/10.1016/j.colsurfb.2008.06.004
Resumo: Vesicles composed of sodium oleate (NaO) and monoolein (MO) are adequate candidates for drug nanoencapsulation and controlled release due to their stability and perceived biocompatibility. The object of the present study is to design hydrogels based on those anionic vesicles and polymers of both non-associative and associative type. The selected macromolecules were k-carrageenan (KC), carboxymethyl cellulose (CMC) and hydrophobically modified carboxymethyl cellulose (HMCMC). While the polymer-vesicle association was probed by rheology, the influence of the polymer on the vesicle stability was monitored by cryo-TEM and calorimetric measurements.
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spelling Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharidesBiovesiclek-CarrageenanCarboxymethyl celluloseSodium oleateMonooleinNetworksVesicles composed of sodium oleate (NaO) and monoolein (MO) are adequate candidates for drug nanoencapsulation and controlled release due to their stability and perceived biocompatibility. The object of the present study is to design hydrogels based on those anionic vesicles and polymers of both non-associative and associative type. The selected macromolecules were k-carrageenan (KC), carboxymethyl cellulose (CMC) and hydrophobically modified carboxymethyl cellulose (HMCMC). While the polymer-vesicle association was probed by rheology, the influence of the polymer on the vesicle stability was monitored by cryo-TEM and calorimetric measurements.http://www.sciencedirect.com/science/article/B6TFS-4SSY8TX-3/1/b7eba2ff0ace8eb0a10542928dfb200d2008info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/3769http://hdl.handle.net/10316/3769https://doi.org/10.1016/j.colsurfb.2008.06.004engColloids and Surfaces B: Biointerfaces. 66:1 (2008) 134-140Antunes, Filipe E.Coppola, LuigiRossi, Cesare OlivieroRanieri, Giuseppe Antonioinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:48:54Zoai:estudogeral.uc.pt:10316/3769Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:59:15.153173Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
title Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
spellingShingle Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
Antunes, Filipe E.
Biovesicle
k-Carrageenan
Carboxymethyl cellulose
Sodium oleate
Monoolein
Networks
title_short Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
title_full Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
title_fullStr Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
title_full_unstemmed Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
title_sort Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
author Antunes, Filipe E.
author_facet Antunes, Filipe E.
Coppola, Luigi
Rossi, Cesare Oliviero
Ranieri, Giuseppe Antonio
author_role author
author2 Coppola, Luigi
Rossi, Cesare Oliviero
Ranieri, Giuseppe Antonio
author2_role author
author
author
dc.contributor.author.fl_str_mv Antunes, Filipe E.
Coppola, Luigi
Rossi, Cesare Oliviero
Ranieri, Giuseppe Antonio
dc.subject.por.fl_str_mv Biovesicle
k-Carrageenan
Carboxymethyl cellulose
Sodium oleate
Monoolein
Networks
topic Biovesicle
k-Carrageenan
Carboxymethyl cellulose
Sodium oleate
Monoolein
Networks
description Vesicles composed of sodium oleate (NaO) and monoolein (MO) are adequate candidates for drug nanoencapsulation and controlled release due to their stability and perceived biocompatibility. The object of the present study is to design hydrogels based on those anionic vesicles and polymers of both non-associative and associative type. The selected macromolecules were k-carrageenan (KC), carboxymethyl cellulose (CMC) and hydrophobically modified carboxymethyl cellulose (HMCMC). While the polymer-vesicle association was probed by rheology, the influence of the polymer on the vesicle stability was monitored by cryo-TEM and calorimetric measurements.
publishDate 2008
dc.date.none.fl_str_mv 2008
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/3769
http://hdl.handle.net/10316/3769
https://doi.org/10.1016/j.colsurfb.2008.06.004
url http://hdl.handle.net/10316/3769
https://doi.org/10.1016/j.colsurfb.2008.06.004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Colloids and Surfaces B: Biointerfaces. 66:1 (2008) 134-140
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv aplication/PDF
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