Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/3769 https://doi.org/10.1016/j.colsurfb.2008.06.004 |
Resumo: | Vesicles composed of sodium oleate (NaO) and monoolein (MO) are adequate candidates for drug nanoencapsulation and controlled release due to their stability and perceived biocompatibility. The object of the present study is to design hydrogels based on those anionic vesicles and polymers of both non-associative and associative type. The selected macromolecules were k-carrageenan (KC), carboxymethyl cellulose (CMC) and hydrophobically modified carboxymethyl cellulose (HMCMC). While the polymer-vesicle association was probed by rheology, the influence of the polymer on the vesicle stability was monitored by cryo-TEM and calorimetric measurements. |
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Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharidesBiovesiclek-CarrageenanCarboxymethyl celluloseSodium oleateMonooleinNetworksVesicles composed of sodium oleate (NaO) and monoolein (MO) are adequate candidates for drug nanoencapsulation and controlled release due to their stability and perceived biocompatibility. The object of the present study is to design hydrogels based on those anionic vesicles and polymers of both non-associative and associative type. The selected macromolecules were k-carrageenan (KC), carboxymethyl cellulose (CMC) and hydrophobically modified carboxymethyl cellulose (HMCMC). While the polymer-vesicle association was probed by rheology, the influence of the polymer on the vesicle stability was monitored by cryo-TEM and calorimetric measurements.http://www.sciencedirect.com/science/article/B6TFS-4SSY8TX-3/1/b7eba2ff0ace8eb0a10542928dfb200d2008info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/3769http://hdl.handle.net/10316/3769https://doi.org/10.1016/j.colsurfb.2008.06.004engColloids and Surfaces B: Biointerfaces. 66:1 (2008) 134-140Antunes, Filipe E.Coppola, LuigiRossi, Cesare OlivieroRanieri, Giuseppe Antonioinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:48:54Zoai:estudogeral.uc.pt:10316/3769Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:59:15.153173Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides |
title |
Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides |
spellingShingle |
Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides Antunes, Filipe E. Biovesicle k-Carrageenan Carboxymethyl cellulose Sodium oleate Monoolein Networks |
title_short |
Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides |
title_full |
Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides |
title_fullStr |
Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides |
title_full_unstemmed |
Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides |
title_sort |
Gelation of charged bio-nanocompartments induced by associative and non-associative polysaccharides |
author |
Antunes, Filipe E. |
author_facet |
Antunes, Filipe E. Coppola, Luigi Rossi, Cesare Oliviero Ranieri, Giuseppe Antonio |
author_role |
author |
author2 |
Coppola, Luigi Rossi, Cesare Oliviero Ranieri, Giuseppe Antonio |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Antunes, Filipe E. Coppola, Luigi Rossi, Cesare Oliviero Ranieri, Giuseppe Antonio |
dc.subject.por.fl_str_mv |
Biovesicle k-Carrageenan Carboxymethyl cellulose Sodium oleate Monoolein Networks |
topic |
Biovesicle k-Carrageenan Carboxymethyl cellulose Sodium oleate Monoolein Networks |
description |
Vesicles composed of sodium oleate (NaO) and monoolein (MO) are adequate candidates for drug nanoencapsulation and controlled release due to their stability and perceived biocompatibility. The object of the present study is to design hydrogels based on those anionic vesicles and polymers of both non-associative and associative type. The selected macromolecules were k-carrageenan (KC), carboxymethyl cellulose (CMC) and hydrophobically modified carboxymethyl cellulose (HMCMC). While the polymer-vesicle association was probed by rheology, the influence of the polymer on the vesicle stability was monitored by cryo-TEM and calorimetric measurements. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/3769 http://hdl.handle.net/10316/3769 https://doi.org/10.1016/j.colsurfb.2008.06.004 |
url |
http://hdl.handle.net/10316/3769 https://doi.org/10.1016/j.colsurfb.2008.06.004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Colloids and Surfaces B: Biointerfaces. 66:1 (2008) 134-140 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
aplication/PDF |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133883623538688 |