Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications

Detalhes bibliográficos
Autor(a) principal: Silva, Aurora
Data de Publicação: 2020
Outros Autores: Silva, Sofia A., Carpena, M., Garcia-Oliveira, P., Gullón, P., Barroso, M. Fátima, Prieto, M.A., Simal-Gandara, J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/18637
Resumo: n the last few decades, attention on new natural antimicrobial compounds has arisen due to a change in consumer preferences and the increase in the number of resistant microorganisms. Macroalgae play a special role in the pursuit of new active molecules as they have been traditionally consumed and are known for their chemical and nutritional composition and their biological properties, including antimicrobial activity. Among the bioactive molecules of algae, proteins and peptides, polysaccharides, polyphenols, polyunsaturated fatty acids and pigments can be highlighted. However, for the complete obtaining and incorporation of these molecules, it is essential to achieve easy, profitable and sustainable recovery of these compounds. For this purpose, novel liquid–liquid and solid–liquid extraction techniques have been studied, such as supercritical, ultrasound, microwave, enzymatic, high pressure, accelerated solvent and intensity pulsed electric fields extraction techniques. Moreover, different applications have been proposed for these compounds, such as preservatives in the food or cosmetic industries, as antibiotics in the pharmaceutical industry, as antibiofilm, antifouling, coating in active packaging, prebiotics or in nanoparticles. This review presents the main antimicrobial potential of macroalgae, their specific bioactive compounds and novel green extraction technologies to efficiently extract them, with emphasis on the antibacterial and antifungal data and their applications.
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spelling Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and ApplicationsAntimicrobial applicationsAntimicrobial compoundsBioactive compoundsMacroalgaeNovel technologiesn the last few decades, attention on new natural antimicrobial compounds has arisen due to a change in consumer preferences and the increase in the number of resistant microorganisms. Macroalgae play a special role in the pursuit of new active molecules as they have been traditionally consumed and are known for their chemical and nutritional composition and their biological properties, including antimicrobial activity. Among the bioactive molecules of algae, proteins and peptides, polysaccharides, polyphenols, polyunsaturated fatty acids and pigments can be highlighted. However, for the complete obtaining and incorporation of these molecules, it is essential to achieve easy, profitable and sustainable recovery of these compounds. For this purpose, novel liquid–liquid and solid–liquid extraction techniques have been studied, such as supercritical, ultrasound, microwave, enzymatic, high pressure, accelerated solvent and intensity pulsed electric fields extraction techniques. Moreover, different applications have been proposed for these compounds, such as preservatives in the food or cosmetic industries, as antibiotics in the pharmaceutical industry, as antibiofilm, antifouling, coating in active packaging, prebiotics or in nanoparticles. This review presents the main antimicrobial potential of macroalgae, their specific bioactive compounds and novel green extraction technologies to efficiently extract them, with emphasis on the antibacterial and antifungal data and their applications.The research leading to these results received financial support from Programa de Cooperación Interreg V-A España—Portugal (POCTEP) 2014–2020 (projects Ref. 0181_NANOEATERS_01_E and Ref. 0377_IBERPHENOL_6_E); from MICINN supporting the Ramón and Cajal grant for M.A. Prieto (RYC-2017-22891); from Xunta de Galicia and University of Vigo supporting the pre-doctoral grant of P. García-Oliveira (ED481A-2019/295); by EcoChestnut Project (Erasmus + KA202) supporting the work of M. Carpena and from postdoctoral support for P. Gullón working under the project Bio Based Industries Joint Undertaking (JU) under grant agreement No 888003 UP4HEALTH Project (H2020-BBI-JTI-2019). This work also received financial support from REQUIMTE/LAQV, National Funds (FCT, Fundação para a Ciência e Tecnologia) through project UID/QUI/50006/2019 and by FEDER—Fundo Europeu de Desenvolvimento Regional funds through the COMPETE 2020—Operational Programme for Competitiveness and Internationalisation (POCI), and by Portuguese funds through FCT—Fundação para a Ciência e a Tecnologia in the framework of the project POCI-01-0145-FEDER-030240—PTDC/OCE-ETA/30240/2017.MDPIRepositório Científico do Instituto Politécnico do PortoSilva, AuroraSilva, Sofia A.Carpena, M.Garcia-Oliveira, P.Gullón, P.Barroso, M. FátimaPrieto, M.A.Simal-Gandara, J.2021-10-01T09:04:54Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/18637eng10.3390/antibiotics9100642info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:10:46Zoai:recipp.ipp.pt:10400.22/18637Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:38:11.521785Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications
title Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications
spellingShingle Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications
Silva, Aurora
Antimicrobial applications
Antimicrobial compounds
Bioactive compounds
Macroalgae
Novel technologies
title_short Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications
title_full Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications
title_fullStr Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications
title_full_unstemmed Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications
title_sort Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications
author Silva, Aurora
author_facet Silva, Aurora
Silva, Sofia A.
Carpena, M.
Garcia-Oliveira, P.
Gullón, P.
Barroso, M. Fátima
Prieto, M.A.
Simal-Gandara, J.
author_role author
author2 Silva, Sofia A.
Carpena, M.
Garcia-Oliveira, P.
Gullón, P.
Barroso, M. Fátima
Prieto, M.A.
Simal-Gandara, J.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Silva, Aurora
Silva, Sofia A.
Carpena, M.
Garcia-Oliveira, P.
Gullón, P.
Barroso, M. Fátima
Prieto, M.A.
Simal-Gandara, J.
dc.subject.por.fl_str_mv Antimicrobial applications
Antimicrobial compounds
Bioactive compounds
Macroalgae
Novel technologies
topic Antimicrobial applications
Antimicrobial compounds
Bioactive compounds
Macroalgae
Novel technologies
description n the last few decades, attention on new natural antimicrobial compounds has arisen due to a change in consumer preferences and the increase in the number of resistant microorganisms. Macroalgae play a special role in the pursuit of new active molecules as they have been traditionally consumed and are known for their chemical and nutritional composition and their biological properties, including antimicrobial activity. Among the bioactive molecules of algae, proteins and peptides, polysaccharides, polyphenols, polyunsaturated fatty acids and pigments can be highlighted. However, for the complete obtaining and incorporation of these molecules, it is essential to achieve easy, profitable and sustainable recovery of these compounds. For this purpose, novel liquid–liquid and solid–liquid extraction techniques have been studied, such as supercritical, ultrasound, microwave, enzymatic, high pressure, accelerated solvent and intensity pulsed electric fields extraction techniques. Moreover, different applications have been proposed for these compounds, such as preservatives in the food or cosmetic industries, as antibiotics in the pharmaceutical industry, as antibiofilm, antifouling, coating in active packaging, prebiotics or in nanoparticles. This review presents the main antimicrobial potential of macroalgae, their specific bioactive compounds and novel green extraction technologies to efficiently extract them, with emphasis on the antibacterial and antifungal data and their applications.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2021-10-01T09:04:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/18637
url http://hdl.handle.net/10400.22/18637
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3390/antibiotics9100642
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
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