Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases
| Autor(a) principal: | |
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| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/1822/68528 |
Resumo: | Supplementary material associated with this article can be found in the online version at: doi:10.1016/j.dib.2020.106598. |
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Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseasesNeurodegenerationNeuroprotectionAntioxidant propertiesC. elegansHyptis spp.Lycium spp.Plant extractsCiências Naturais::Ciências BiológicasScience & TechnologySupplementary material associated with this article can be found in the online version at: doi:10.1016/j.dib.2020.106598.Here, we present the data on the biological effects of Hyptis spp. and Lycium spp. plant extracts in Caenorhabditis elegans (C. elegans) models of neurodegenerative diseases, which is related to the work presented in the article "Neurotherapeutic effect of Hyptis spp. leaf extracts in Caenorhabditis elegans models of tauopathy and polyglutamine disease: role of the glutathione redox cycle" [1]. This dataset was generated to define non-toxic concentrations of these plant extracts and to assess their impact on the motor phenotype and oxidative stress resistance of transgenic C. elegans models of two genetically defined neurodegenerative diseases: Machado-Joseph disease and Frontotemporal dementia with Parkinsonism associated to the chromosome 17. The impact of the plant extracts on toxicity was assessed using the food-clearance assay, absorbance being measured daily for seven days at 595 nm to quantify Escherichia coli (E. coli) strain OP50 bacteria consumption. Worm length and motor behaviour, including spontaneous and stimulated movement, were analysed using videos acquired with an Olympus SZX7 stereomicroscope with an integrated camera (Olympus SC30) and processed using the Image J® software and the Wrmtrck plugin. The resistance to oxidative stress induced by 240 µM juglone was assessed by determining the percentage of live animals after 1 hour of exposure.The authors thank all members of the Maciel and Dias laboratories for helpful tips and discussion; we also thank the Caenorhabditis Genetics Center (CGC), which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440), for providing some of the C. elegans strains; Dr. Brian Kraemer who kindly gave us the C. elegans model of FTDP-17; We thank Federal Institute of Education, Science and Technology Goiano (IF Goiano) for the cultivation and harvesting of Hyptis spp. plant biomass.info:eu-repo/semantics/publishedVersionElsevierUniversidade do MinhoVilasboas-Campos, DanielaCosta, Marta DanielaTeixeira-Castro, AndreiaRios, RejaineSilva, Fabiano GuimarãesAierken, AiliZhang, XiaoyingBessa, CarlosDias, AlbertoMaciel, P.2020-122020-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/68528engVilasboas-Campos, Daniela; Costa, Marta Daniela; Teixeira-Castro, Andreia; Rios, Rejaine; Silva, Fabiano Guimarães; Aierken, Aili; Zhang, Xiaoying; Bessa, Carlos; Dias, Alberto; Maciel, Patrícia, Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases. Data in Brief, 33(106598), 2020. DOI: 10.1016/j.dib.2020.1065982352-340910.1016/j.dib.2020.106598https://www.sciencedirect.com/science/article/pii/S2352340920314785info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:40:29ZPortal AgregadorONG |
| dc.title.none.fl_str_mv |
Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases |
| title |
Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases |
| spellingShingle |
Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases Vilasboas-Campos, Daniela Neurodegeneration Neuroprotection Antioxidant properties C. elegans Hyptis spp. Lycium spp. Plant extracts Ciências Naturais::Ciências Biológicas Science & Technology |
| title_short |
Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases |
| title_full |
Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases |
| title_fullStr |
Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases |
| title_full_unstemmed |
Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases |
| title_sort |
Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases |
| author |
Vilasboas-Campos, Daniela |
| author_facet |
Vilasboas-Campos, Daniela Costa, Marta Daniela Teixeira-Castro, Andreia Rios, Rejaine Silva, Fabiano Guimarães Aierken, Aili Zhang, Xiaoying Bessa, Carlos Dias, Alberto Maciel, P. |
| author_role |
author |
| author2 |
Costa, Marta Daniela Teixeira-Castro, Andreia Rios, Rejaine Silva, Fabiano Guimarães Aierken, Aili Zhang, Xiaoying Bessa, Carlos Dias, Alberto Maciel, P. |
| author2_role |
author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade do Minho |
| dc.contributor.author.fl_str_mv |
Vilasboas-Campos, Daniela Costa, Marta Daniela Teixeira-Castro, Andreia Rios, Rejaine Silva, Fabiano Guimarães Aierken, Aili Zhang, Xiaoying Bessa, Carlos Dias, Alberto Maciel, P. |
| dc.subject.por.fl_str_mv |
Neurodegeneration Neuroprotection Antioxidant properties C. elegans Hyptis spp. Lycium spp. Plant extracts Ciências Naturais::Ciências Biológicas Science & Technology |
| topic |
Neurodegeneration Neuroprotection Antioxidant properties C. elegans Hyptis spp. Lycium spp. Plant extracts Ciências Naturais::Ciências Biológicas Science & Technology |
| description |
Supplementary material associated with this article can be found in the online version at: doi:10.1016/j.dib.2020.106598. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020-12 2020-12-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/1822/68528 |
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http://hdl.handle.net/1822/68528 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Vilasboas-Campos, Daniela; Costa, Marta Daniela; Teixeira-Castro, Andreia; Rios, Rejaine; Silva, Fabiano Guimarães; Aierken, Aili; Zhang, Xiaoying; Bessa, Carlos; Dias, Alberto; Maciel, Patrícia, Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases. Data in Brief, 33(106598), 2020. DOI: 10.1016/j.dib.2020.106598 2352-3409 10.1016/j.dib.2020.106598 https://www.sciencedirect.com/science/article/pii/S2352340920314785 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Elsevier |
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Elsevier |
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