Non-invasive ventilation in acute respiratory failure in children

Detalhes bibliográficos
Autor(a) principal: Abadesso, C
Data de Publicação: 2012
Outros Autores: Nunes, P, Silvestre, C, Matias, E, Loureiro, H, Almeida, HI
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.10/647
Resumo: BACKGROUND: There is only sparse data on the use of non-invasive ventilation (NIV) in acute respiratory failure (ARF) in infants and children. For this setting we investigated feasibility and efficacy of NIV and aimed to identify early predictors for treatment failure. PATIENTS AND METHODS: Retrospective chart review was performed for all patients treated with NIV for ARF from 2003 to 2010 on an 8-bed pediatric intensive care unit of a tertiary university hospital. RESULTS: Seventy-four patients were treated with NIV. One patient did not tolerate mask ventilation and needed immediate invasive ventilation. Intubation rate of the remaining patients was 23% and mortality 15%. Institution of NIV led to significant improvement of both respiratory and heart rate in all patients within the first hour and to further stabilization within the next 8-10 hr. In patients with NIV success blood gases improved significantly 1-2 hr after starting NIV. Multivariate analysis identified low pH after 1-2 hr to be an individual risk factor for NIV failure. Other factors tested were age, underlying disease, acute respiratory insufficiency versus post-extubation failure (PEF), and 1-2 hr after starting NIV oxygen saturation, respiratory rate, PCO(2) , and FiO(2) . Patients with PEF tended to show better outcomes compared to those with acute respiratory insufficiency. CONCLUSION: NIV can be effective in infants and children with ARF. Low pH 1-2 hr after start of NIV is associated with NIV failure. It may therefore be useful in the decision to continue or stop mask ventilation.
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spelling Non-invasive ventilation in acute respiratory failure in childrenRespiração artificialCriançaUnidade de cuidados intensivos pediátricosInsuficiência respiratóriaNon-invasive ventilationAcute respiratory failureChildPediatric intensive care unitBACKGROUND: There is only sparse data on the use of non-invasive ventilation (NIV) in acute respiratory failure (ARF) in infants and children. For this setting we investigated feasibility and efficacy of NIV and aimed to identify early predictors for treatment failure. PATIENTS AND METHODS: Retrospective chart review was performed for all patients treated with NIV for ARF from 2003 to 2010 on an 8-bed pediatric intensive care unit of a tertiary university hospital. RESULTS: Seventy-four patients were treated with NIV. One patient did not tolerate mask ventilation and needed immediate invasive ventilation. Intubation rate of the remaining patients was 23% and mortality 15%. Institution of NIV led to significant improvement of both respiratory and heart rate in all patients within the first hour and to further stabilization within the next 8-10 hr. In patients with NIV success blood gases improved significantly 1-2 hr after starting NIV. Multivariate analysis identified low pH after 1-2 hr to be an individual risk factor for NIV failure. Other factors tested were age, underlying disease, acute respiratory insufficiency versus post-extubation failure (PEF), and 1-2 hr after starting NIV oxygen saturation, respiratory rate, PCO(2) , and FiO(2) . Patients with PEF tended to show better outcomes compared to those with acute respiratory insufficiency. CONCLUSION: NIV can be effective in infants and children with ARF. Low pH 1-2 hr after start of NIV is associated with NIV failure. It may therefore be useful in the decision to continue or stop mask ventilation.PAGEPressRepositório do Hospital Prof. Doutor Fernando FonsecaAbadesso, CNunes, PSilvestre, CMatias, ELoureiro, HAlmeida, HI2012-08-10T12:56:49Z2012-01-01T00:00:00Z2012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.10/647engPediatr Rep. 2012 Apr 2; 4(2):e162036-749Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-20T15:51:32Zoai:repositorio.hff.min-saude.pt:10400.10/647Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:51:53.329332Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Non-invasive ventilation in acute respiratory failure in children
title Non-invasive ventilation in acute respiratory failure in children
spellingShingle Non-invasive ventilation in acute respiratory failure in children
Abadesso, C
Respiração artificial
Criança
Unidade de cuidados intensivos pediátricos
Insuficiência respiratória
Non-invasive ventilation
Acute respiratory failure
Child
Pediatric intensive care unit
title_short Non-invasive ventilation in acute respiratory failure in children
title_full Non-invasive ventilation in acute respiratory failure in children
title_fullStr Non-invasive ventilation in acute respiratory failure in children
title_full_unstemmed Non-invasive ventilation in acute respiratory failure in children
title_sort Non-invasive ventilation in acute respiratory failure in children
author Abadesso, C
author_facet Abadesso, C
Nunes, P
Silvestre, C
Matias, E
Loureiro, H
Almeida, HI
author_role author
author2 Nunes, P
Silvestre, C
Matias, E
Loureiro, H
Almeida, HI
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Hospital Prof. Doutor Fernando Fonseca
dc.contributor.author.fl_str_mv Abadesso, C
Nunes, P
Silvestre, C
Matias, E
Loureiro, H
Almeida, HI
dc.subject.por.fl_str_mv Respiração artificial
Criança
Unidade de cuidados intensivos pediátricos
Insuficiência respiratória
Non-invasive ventilation
Acute respiratory failure
Child
Pediatric intensive care unit
topic Respiração artificial
Criança
Unidade de cuidados intensivos pediátricos
Insuficiência respiratória
Non-invasive ventilation
Acute respiratory failure
Child
Pediatric intensive care unit
description BACKGROUND: There is only sparse data on the use of non-invasive ventilation (NIV) in acute respiratory failure (ARF) in infants and children. For this setting we investigated feasibility and efficacy of NIV and aimed to identify early predictors for treatment failure. PATIENTS AND METHODS: Retrospective chart review was performed for all patients treated with NIV for ARF from 2003 to 2010 on an 8-bed pediatric intensive care unit of a tertiary university hospital. RESULTS: Seventy-four patients were treated with NIV. One patient did not tolerate mask ventilation and needed immediate invasive ventilation. Intubation rate of the remaining patients was 23% and mortality 15%. Institution of NIV led to significant improvement of both respiratory and heart rate in all patients within the first hour and to further stabilization within the next 8-10 hr. In patients with NIV success blood gases improved significantly 1-2 hr after starting NIV. Multivariate analysis identified low pH after 1-2 hr to be an individual risk factor for NIV failure. Other factors tested were age, underlying disease, acute respiratory insufficiency versus post-extubation failure (PEF), and 1-2 hr after starting NIV oxygen saturation, respiratory rate, PCO(2) , and FiO(2) . Patients with PEF tended to show better outcomes compared to those with acute respiratory insufficiency. CONCLUSION: NIV can be effective in infants and children with ARF. Low pH 1-2 hr after start of NIV is associated with NIV failure. It may therefore be useful in the decision to continue or stop mask ventilation.
publishDate 2012
dc.date.none.fl_str_mv 2012-08-10T12:56:49Z
2012-01-01T00:00:00Z
2012-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.10/647
url http://hdl.handle.net/10400.10/647
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Pediatr Rep. 2012 Apr 2; 4(2):e16
2036-749X
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dc.publisher.none.fl_str_mv PAGEPress
publisher.none.fl_str_mv PAGEPress
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instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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