Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries

Detalhes bibliográficos
Autor(a) principal: Radó, Márta K.
Data de Publicação: 2022
Outros Autores: van Lenthe, Frank J., Laverty, Anthony A., Filippidis, Filippos T., Millett, Christopher, Sheikh, Aziz, Been, Jasper V.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/153981
Resumo: Funding Information: We acknowledge the financial support from Dutch Heart Foundation, Lung Foundation Netherlands, Dutch Cancer Society, Dutch Diabetes Research Foundation, Netherlands Thrombosis Foundation, and Health Data Research UK. Publisher Copyright: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license
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spelling Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countriesa synthetic control studyPublic Health, Environmental and Occupational HealthSDG 3 - Good Health and Well-beingFunding Information: We acknowledge the financial support from Dutch Heart Foundation, Lung Foundation Netherlands, Dutch Cancer Society, Dutch Diabetes Research Foundation, Netherlands Thrombosis Foundation, and Health Data Research UK. Publisher Copyright: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: There are few quantitative studies into the effect of comprehensive smoke-free legislation on neonatal and infant mortality in middle-income countries. We aimed to estimate the effects of implementing comprehensive smoke-free legislation on neonatal mortality and infant mortality across all middle-income countries. Methods: We applied the synthetic control method using 1990–2018 country-level panel data for 106 middle-income countries from the WHO, World Bank, and Penn World datasets. Outcome variables were neonatal (age 0–28 days) mortality and infant (age 0–12 months) mortality rates per 1000 livebirths per year. For each middle-income country with comprehensive smoke-free legislation, a synthetic control country was constructed from middle-income countries without comprehensive smoke-free legislation, but with similar prelegislation trends in the outcome and predictor variables. Overall legislation effect was the mean average of country-specific effects weighted by the number of livebirths. We compared the distribution of the legislation effects with that of the placebo effects to assess the likelihood that the observed effect was related to the implementation of smoke-free legislation and not merely influenced by other processes. Findings: 31 (29%) of 106 middle-income countries introduced comprehensive smoke-free legislation and had outcome data for at least 3 years after the intervention. We were able to construct a synthetic control country for 18 countries for neonatal mortality and for 15 countries for infant mortality. Comprehensive smoke-free legislation was followed by a mean yearly decrease of 1·63% in neonatal mortality and a mean yearly decrease of 1·33% in infant mortality. An estimated 12 392 neonatal deaths in 18 countries and 8932 infant deaths in 15 countries were avoided over 3 years following the implementation of comprehensive smoke-free legislation. We estimated that an additional 104 063 infant deaths (including 95 850 neonatal deaths) could have been avoided over 3 years if the 72 control middle-income countries had introduced this legislation in 2015. 220 (43%) of 514 placebo effects for neonatal mortality and 112 (39%) of 289 for infant mortality were larger than the estimated aggregated legislation effect, indicating a degree of uncertainty around our estimates. Sensitivity analyses showed results that were consistent with the main analysis and suggested a dose–response association related to comprehensiveness of the legislation. Interpretation: Implementing comprehensive smoke-free legislation in middle-income countries could substantially reduce preventable deaths in neonates and infants. Funding: Dutch Heart Foundation, Lung Foundation Netherlands, Dutch Cancer Society, Dutch Diabetes Research Foundation, Netherlands Thrombosis Foundation, Health Data Research UK.Centro de Investigação em Saúde Pública (CISP/PHRC)Comprehensive Health Research Centre (CHRC) - Pólo ENSPEscola Nacional de Saúde Pública (ENSP)RUNRadó, Márta K.van Lenthe, Frank J.Laverty, Anthony A.Filippidis, Filippos T.Millett, ChristopherSheikh, AzizBeen, Jasper V.2023-06-15T22:20:50Z2022-072022-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/153981eng2468-2667PURE: 63727343https://doi.org/10.1016/S2468-2667(22)00112-8info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:36:26Zoai:run.unl.pt:10362/153981Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:55:26.948798Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries
a synthetic control study
title Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries
spellingShingle Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries
Radó, Márta K.
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
title_short Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries
title_full Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries
title_fullStr Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries
title_full_unstemmed Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries
title_sort Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries
author Radó, Márta K.
author_facet Radó, Márta K.
van Lenthe, Frank J.
Laverty, Anthony A.
Filippidis, Filippos T.
Millett, Christopher
Sheikh, Aziz
Been, Jasper V.
author_role author
author2 van Lenthe, Frank J.
Laverty, Anthony A.
Filippidis, Filippos T.
Millett, Christopher
Sheikh, Aziz
Been, Jasper V.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Centro de Investigação em Saúde Pública (CISP/PHRC)
Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Escola Nacional de Saúde Pública (ENSP)
RUN
dc.contributor.author.fl_str_mv Radó, Márta K.
van Lenthe, Frank J.
Laverty, Anthony A.
Filippidis, Filippos T.
Millett, Christopher
Sheikh, Aziz
Been, Jasper V.
dc.subject.por.fl_str_mv Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
topic Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
description Funding Information: We acknowledge the financial support from Dutch Heart Foundation, Lung Foundation Netherlands, Dutch Cancer Society, Dutch Diabetes Research Foundation, Netherlands Thrombosis Foundation, and Health Data Research UK. Publisher Copyright: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license
publishDate 2022
dc.date.none.fl_str_mv 2022-07
2022-07-01T00:00:00Z
2023-06-15T22:20:50Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/153981
url http://hdl.handle.net/10362/153981
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2468-2667
PURE: 63727343
https://doi.org/10.1016/S2468-2667(22)00112-8
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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