Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives

Detalhes bibliográficos
Autor(a) principal: Ferreira, Paula M. T.
Data de Publicação: 2000
Outros Autores: Maia, Hernâni L. S., Monteiro, Luís S., Sacramento, Joana, Sebastião, Joana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/2187
Resumo: Several b-substituted alanines are synthesised in high yields by a Michael addition of nucleophiles to N-acyl,N-tert-butyloxycarbonyl-dehydroalanine methyl ester, using mild reaction conditions and simple work-up procedures. The same method can be applied to dipeptides containing dehydroalanine.
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spelling Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivativesScience & TechnologySeveral b-substituted alanines are synthesised in high yields by a Michael addition of nucleophiles to N-acyl,N-tert-butyloxycarbonyl-dehydroalanine methyl ester, using mild reaction conditions and simple work-up procedures. The same method can be applied to dipeptides containing dehydroalanine.Royal Society of ChemistryUniversidade do MinhoFerreira, Paula M. T.Maia, Hernâni L. S.Monteiro, Luís S.Sacramento, JoanaSebastião, Joana20002000-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/2187eng“Journal of the chemical society. Perkin transactions”. 1 (2000) 3317-3324.1470-435810.1039/b003353ginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:55:08Zoai:repositorium.sdum.uminho.pt:1822/2187Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:44:39.903585Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
title Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
spellingShingle Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
Ferreira, Paula M. T.
Science & Technology
title_short Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
title_full Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
title_fullStr Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
title_full_unstemmed Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
title_sort Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
author Ferreira, Paula M. T.
author_facet Ferreira, Paula M. T.
Maia, Hernâni L. S.
Monteiro, Luís S.
Sacramento, Joana
Sebastião, Joana
author_role author
author2 Maia, Hernâni L. S.
Monteiro, Luís S.
Sacramento, Joana
Sebastião, Joana
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Ferreira, Paula M. T.
Maia, Hernâni L. S.
Monteiro, Luís S.
Sacramento, Joana
Sebastião, Joana
dc.subject.por.fl_str_mv Science & Technology
topic Science & Technology
description Several b-substituted alanines are synthesised in high yields by a Michael addition of nucleophiles to N-acyl,N-tert-butyloxycarbonyl-dehydroalanine methyl ester, using mild reaction conditions and simple work-up procedures. The same method can be applied to dipeptides containing dehydroalanine.
publishDate 2000
dc.date.none.fl_str_mv 2000
2000-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/2187
url https://hdl.handle.net/1822/2187
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv “Journal of the chemical society. Perkin transactions”. 1 (2000) 3317-3324.
1470-4358
10.1039/b003353g
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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