Monoclonal antibodies. General approach and radioimmunotherapy.

Detalhes bibliográficos
Autor(a) principal: Sousa, O
Data de Publicação: 1998
Outros Autores: Vieira, E
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2242
Resumo: Two major obstacles to systemic cancer therapy are the lack of specificity of therapeutic modalities and the intrapatient and interpatient heterogeneity of cancer cells. Because of their natural specificity, antibodies directed against tumor specific or tumor associated antigens have been raising interest in oncology. This article makes an overview of the basic principles of monoclonal antibodies, their limitations and perspectives, with particular attention to Immunoradioconjugates. The most important Immunoradiotherapy clinical studies are also reviewed.
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spelling Monoclonal antibodies. General approach and radioimmunotherapy.Anticorpos Monoclonais. Abordagem Geral e Radioimunoterapia.Two major obstacles to systemic cancer therapy are the lack of specificity of therapeutic modalities and the intrapatient and interpatient heterogeneity of cancer cells. Because of their natural specificity, antibodies directed against tumor specific or tumor associated antigens have been raising interest in oncology. This article makes an overview of the basic principles of monoclonal antibodies, their limitations and perspectives, with particular attention to Immunoradioconjugates. The most important Immunoradiotherapy clinical studies are also reviewed.Two major obstacles to systemic cancer therapy are the lack of specificity of therapeutic modalities and the intrapatient and interpatient heterogeneity of cancer cells. Because of their natural specificity, antibodies directed against tumor specific or tumor associated antigens have been raising interest in oncology. This article makes an overview of the basic principles of monoclonal antibodies, their limitations and perspectives, with particular attention to Immunoradioconjugates. The most important Immunoradiotherapy clinical studies are also reviewed.Ordem dos Médicos1998-04-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2242oai:ojs.www.actamedicaportuguesa.com:article/2242Acta Médica Portuguesa; Vol. 11 No. 4 (1998): Abril; 337-47Acta Médica Portuguesa; Vol. 11 N.º 4 (1998): Abril; 337-471646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2242https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2242/1661Sousa, OVieira, Einfo:eu-repo/semantics/openAccess2022-12-20T11:00:06Zoai:ojs.www.actamedicaportuguesa.com:article/2242Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:17:36.967364Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Monoclonal antibodies. General approach and radioimmunotherapy.
Anticorpos Monoclonais. Abordagem Geral e Radioimunoterapia.
title Monoclonal antibodies. General approach and radioimmunotherapy.
spellingShingle Monoclonal antibodies. General approach and radioimmunotherapy.
Sousa, O
title_short Monoclonal antibodies. General approach and radioimmunotherapy.
title_full Monoclonal antibodies. General approach and radioimmunotherapy.
title_fullStr Monoclonal antibodies. General approach and radioimmunotherapy.
title_full_unstemmed Monoclonal antibodies. General approach and radioimmunotherapy.
title_sort Monoclonal antibodies. General approach and radioimmunotherapy.
author Sousa, O
author_facet Sousa, O
Vieira, E
author_role author
author2 Vieira, E
author2_role author
dc.contributor.author.fl_str_mv Sousa, O
Vieira, E
description Two major obstacles to systemic cancer therapy are the lack of specificity of therapeutic modalities and the intrapatient and interpatient heterogeneity of cancer cells. Because of their natural specificity, antibodies directed against tumor specific or tumor associated antigens have been raising interest in oncology. This article makes an overview of the basic principles of monoclonal antibodies, their limitations and perspectives, with particular attention to Immunoradioconjugates. The most important Immunoradiotherapy clinical studies are also reviewed.
publishDate 1998
dc.date.none.fl_str_mv 1998-04-30
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url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2242
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 11 No. 4 (1998): Abril; 337-47
Acta Médica Portuguesa; Vol. 11 N.º 4 (1998): Abril; 337-47
1646-0758
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