Transient Receptor Potential (TRP) and Thermoregulation in Animals: Structural Biology and Neurophysiological Aspects

• Autor(a) principal: Lezama-Garcia, Karina
• Data de Publicação: 2021
• Outros Autores: Mota-Rojas, Daniel, Pereira, Alfredo, Martinez Burnes, Julio, Ghezi, Marcelo, Geraldo, Ana, Hernandez-Avalos, Ismael, Olmos-Hernandez, Adriana, Wang, Dehua
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10174/34240; https://doi.org/Lezama-García, K.; Mota-Rojas, D.; Pereira, A.M.F.; Martínez-Burnes, J.; Ghezzi, M.; Domínguez, A.; Gómez, J.; de Mira Geraldo, A.; Lendez, P.; Hernández-Ávalos, I.; et al. Transient Receptor Potential (TRP) and Thermoregulation in Animals: Structural Biology and Neurophysiological Aspects. Animals 2022, 12, 106. https://doi.org/ 10.3390/ani12010106; https://doi.org/ 10.3390/ani12010106
• topic: TRP; Thermoregulation; ions channels; mammals

In this review, recent discoveries regarding transient receptor potential are discussed and analyzed to comprehend their role in the thermoregulatory mechanisms of animals. Understanding how these receptors are activated and the pathways through which they recognize specific thermal sensations (such as cold, warm, and hot temperatures) will help researchers verify their participation in inflammatory and pathological processes. Research on transient receptor potential and their functions is ongoing, and many current studies are designed to develop therapeutic approaches that will act directly on these receptors to improve the quality of life of non-human animals.