Anaemia of chronic diseases

Detalhes bibliográficos
Autor(a) principal: Sousa, Gabriela
Data de Publicação: 1999
Outros Autores: Alfaiate, Teresa, Ferreira, Mário Rui, Carvalho, Teresa, Veiga e Moura, António
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/2074
Resumo: The authors review and discuss the current concepts concerning anaemia which coexists with multiple chronic diseases, denominated "Anaemia of Chronic Diseases". This is the most common form of anaemia in hospitalised medical patients. lt se/dom requires treatment as it normally resolves once the underlying disease has been successfully controlled. The most important pathogenic mechanism is a block in the re-utilisation of haemoglobin iron. A mechanism, mediated by the release of interleukins and other infiammation mediators, in response to tissue damage. ln terms of differential diagnosis, the problem is to distinguish between "Anaemia of Chronic Diseases" and "Sideropenic Anaemia" as the appropriate treatment differs. The therapeutic role of erythropoietin is discussed.
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spelling Anaemia of chronic diseasesAnemia das doenças crónicasanemiadoença crónicamacrófagosinterleuquinaspatogeniaeritropoietinaAnaemiachronic diseasemacrophagesinterleukinspathogenesiserythropoietinaThe authors review and discuss the current concepts concerning anaemia which coexists with multiple chronic diseases, denominated "Anaemia of Chronic Diseases". This is the most common form of anaemia in hospitalised medical patients. lt se/dom requires treatment as it normally resolves once the underlying disease has been successfully controlled. The most important pathogenic mechanism is a block in the re-utilisation of haemoglobin iron. A mechanism, mediated by the release of interleukins and other infiammation mediators, in response to tissue damage. ln terms of differential diagnosis, the problem is to distinguish between "Anaemia of Chronic Diseases" and "Sideropenic Anaemia" as the appropriate treatment differs. The therapeutic role of erythropoietin is discussed.Os autores revêem e discutem os progressos e conceitos actuais de um grupo de anemias que acompanham uma variedade de doenças crónicas e, por isso, é denominado "Anemia das Doenças Crónicas". O interesse deste tipo de anemias advém do facto de ser a principal causa de anemia em doentes hospitalizados e do seu tratamento passar pela resolução da doença subjacente. O principal mecanismo patogénico é o bloqueio na reutilização do ferro hematínico, que é provocado pela libertação de interleuquinas e outros mediadores de inflamação, em resposta à lesão tecidular crónica. Em termos de diagnóstico diferencial, o problema coloca-se com a anemia por défice de ferro, da qual deve ser distinguida, dadas as diferentes condutas terapêuticas. Analizaremos, ainda, as possibilidades terapêuticas da eritropoietina.Sociedade Portuguesa de Medicina Interna1999-09-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spmi.pt/index.php/rpmi/article/view/2074Internal Medicine; Vol. 6 No. 3 (1999): Julho/ Setembro; 190-196Medicina Interna; Vol. 6 N.º 3 (1999): Julho/ Setembro; 190-1962183-99800872-671Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spmi.pt/index.php/rpmi/article/view/2074https://revista.spmi.pt/index.php/rpmi/article/view/2074/1461Sousa, GabrielaAlfaiate, TeresaFerreira, Mário RuiCarvalho, TeresaVeiga e Moura, Antónioinfo:eu-repo/semantics/openAccess2023-07-01T06:11:34Zoai:oai.revista.spmi.pt:article/2074Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:02:09.005450Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Anaemia of chronic diseases
Anemia das doenças crónicas
title Anaemia of chronic diseases
spellingShingle Anaemia of chronic diseases
Sousa, Gabriela
anemia
doença crónica
macrófagos
interleuquinas
patogenia
eritropoietina
Anaemia
chronic disease
macrophages
interleukins
pathogenesis
erythropoietina
title_short Anaemia of chronic diseases
title_full Anaemia of chronic diseases
title_fullStr Anaemia of chronic diseases
title_full_unstemmed Anaemia of chronic diseases
title_sort Anaemia of chronic diseases
author Sousa, Gabriela
author_facet Sousa, Gabriela
Alfaiate, Teresa
Ferreira, Mário Rui
Carvalho, Teresa
Veiga e Moura, António
author_role author
author2 Alfaiate, Teresa
Ferreira, Mário Rui
Carvalho, Teresa
Veiga e Moura, António
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Sousa, Gabriela
Alfaiate, Teresa
Ferreira, Mário Rui
Carvalho, Teresa
Veiga e Moura, António
dc.subject.por.fl_str_mv anemia
doença crónica
macrófagos
interleuquinas
patogenia
eritropoietina
Anaemia
chronic disease
macrophages
interleukins
pathogenesis
erythropoietina
topic anemia
doença crónica
macrófagos
interleuquinas
patogenia
eritropoietina
Anaemia
chronic disease
macrophages
interleukins
pathogenesis
erythropoietina
description The authors review and discuss the current concepts concerning anaemia which coexists with multiple chronic diseases, denominated "Anaemia of Chronic Diseases". This is the most common form of anaemia in hospitalised medical patients. lt se/dom requires treatment as it normally resolves once the underlying disease has been successfully controlled. The most important pathogenic mechanism is a block in the re-utilisation of haemoglobin iron. A mechanism, mediated by the release of interleukins and other infiammation mediators, in response to tissue damage. ln terms of differential diagnosis, the problem is to distinguish between "Anaemia of Chronic Diseases" and "Sideropenic Anaemia" as the appropriate treatment differs. The therapeutic role of erythropoietin is discussed.
publishDate 1999
dc.date.none.fl_str_mv 1999-09-30
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/2074
url https://revista.spmi.pt/index.php/rpmi/article/view/2074
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/2074
https://revista.spmi.pt/index.php/rpmi/article/view/2074/1461
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
dc.source.none.fl_str_mv Internal Medicine; Vol. 6 No. 3 (1999): Julho/ Setembro; 190-196
Medicina Interna; Vol. 6 N.º 3 (1999): Julho/ Setembro; 190-196
2183-9980
0872-671X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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