Anaemia of chronic diseases
Autor(a) principal: | |
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Data de Publicação: | 1999 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://revista.spmi.pt/index.php/rpmi/article/view/2074 |
Resumo: | The authors review and discuss the current concepts concerning anaemia which coexists with multiple chronic diseases, denominated "Anaemia of Chronic Diseases". This is the most common form of anaemia in hospitalised medical patients. lt se/dom requires treatment as it normally resolves once the underlying disease has been successfully controlled. The most important pathogenic mechanism is a block in the re-utilisation of haemoglobin iron. A mechanism, mediated by the release of interleukins and other infiammation mediators, in response to tissue damage. ln terms of differential diagnosis, the problem is to distinguish between "Anaemia of Chronic Diseases" and "Sideropenic Anaemia" as the appropriate treatment differs. The therapeutic role of erythropoietin is discussed. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
spelling |
Anaemia of chronic diseasesAnemia das doenças crónicasanemiadoença crónicamacrófagosinterleuquinaspatogeniaeritropoietinaAnaemiachronic diseasemacrophagesinterleukinspathogenesiserythropoietinaThe authors review and discuss the current concepts concerning anaemia which coexists with multiple chronic diseases, denominated "Anaemia of Chronic Diseases". This is the most common form of anaemia in hospitalised medical patients. lt se/dom requires treatment as it normally resolves once the underlying disease has been successfully controlled. The most important pathogenic mechanism is a block in the re-utilisation of haemoglobin iron. A mechanism, mediated by the release of interleukins and other infiammation mediators, in response to tissue damage. ln terms of differential diagnosis, the problem is to distinguish between "Anaemia of Chronic Diseases" and "Sideropenic Anaemia" as the appropriate treatment differs. The therapeutic role of erythropoietin is discussed.Os autores revêem e discutem os progressos e conceitos actuais de um grupo de anemias que acompanham uma variedade de doenças crónicas e, por isso, é denominado "Anemia das Doenças Crónicas". O interesse deste tipo de anemias advém do facto de ser a principal causa de anemia em doentes hospitalizados e do seu tratamento passar pela resolução da doença subjacente. O principal mecanismo patogénico é o bloqueio na reutilização do ferro hematínico, que é provocado pela libertação de interleuquinas e outros mediadores de inflamação, em resposta à lesão tecidular crónica. Em termos de diagnóstico diferencial, o problema coloca-se com a anemia por défice de ferro, da qual deve ser distinguida, dadas as diferentes condutas terapêuticas. Analizaremos, ainda, as possibilidades terapêuticas da eritropoietina.Sociedade Portuguesa de Medicina Interna1999-09-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spmi.pt/index.php/rpmi/article/view/2074Internal Medicine; Vol. 6 No. 3 (1999): Julho/ Setembro; 190-196Medicina Interna; Vol. 6 N.º 3 (1999): Julho/ Setembro; 190-1962183-99800872-671Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spmi.pt/index.php/rpmi/article/view/2074https://revista.spmi.pt/index.php/rpmi/article/view/2074/1461Sousa, GabrielaAlfaiate, TeresaFerreira, Mário RuiCarvalho, TeresaVeiga e Moura, Antónioinfo:eu-repo/semantics/openAccess2023-07-01T06:11:34Zoai:oai.revista.spmi.pt:article/2074Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:02:09.005450Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Anaemia of chronic diseases Anemia das doenças crónicas |
title |
Anaemia of chronic diseases |
spellingShingle |
Anaemia of chronic diseases Sousa, Gabriela anemia doença crónica macrófagos interleuquinas patogenia eritropoietina Anaemia chronic disease macrophages interleukins pathogenesis erythropoietina |
title_short |
Anaemia of chronic diseases |
title_full |
Anaemia of chronic diseases |
title_fullStr |
Anaemia of chronic diseases |
title_full_unstemmed |
Anaemia of chronic diseases |
title_sort |
Anaemia of chronic diseases |
author |
Sousa, Gabriela |
author_facet |
Sousa, Gabriela Alfaiate, Teresa Ferreira, Mário Rui Carvalho, Teresa Veiga e Moura, António |
author_role |
author |
author2 |
Alfaiate, Teresa Ferreira, Mário Rui Carvalho, Teresa Veiga e Moura, António |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Sousa, Gabriela Alfaiate, Teresa Ferreira, Mário Rui Carvalho, Teresa Veiga e Moura, António |
dc.subject.por.fl_str_mv |
anemia doença crónica macrófagos interleuquinas patogenia eritropoietina Anaemia chronic disease macrophages interleukins pathogenesis erythropoietina |
topic |
anemia doença crónica macrófagos interleuquinas patogenia eritropoietina Anaemia chronic disease macrophages interleukins pathogenesis erythropoietina |
description |
The authors review and discuss the current concepts concerning anaemia which coexists with multiple chronic diseases, denominated "Anaemia of Chronic Diseases". This is the most common form of anaemia in hospitalised medical patients. lt se/dom requires treatment as it normally resolves once the underlying disease has been successfully controlled. The most important pathogenic mechanism is a block in the re-utilisation of haemoglobin iron. A mechanism, mediated by the release of interleukins and other infiammation mediators, in response to tissue damage. ln terms of differential diagnosis, the problem is to distinguish between "Anaemia of Chronic Diseases" and "Sideropenic Anaemia" as the appropriate treatment differs. The therapeutic role of erythropoietin is discussed. |
publishDate |
1999 |
dc.date.none.fl_str_mv |
1999-09-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revista.spmi.pt/index.php/rpmi/article/view/2074 |
url |
https://revista.spmi.pt/index.php/rpmi/article/view/2074 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spmi.pt/index.php/rpmi/article/view/2074 https://revista.spmi.pt/index.php/rpmi/article/view/2074/1461 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Medicina Interna |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Medicina Interna |
dc.source.none.fl_str_mv |
Internal Medicine; Vol. 6 No. 3 (1999): Julho/ Setembro; 190-196 Medicina Interna; Vol. 6 N.º 3 (1999): Julho/ Setembro; 190-196 2183-9980 0872-671X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
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1799131687554121728 |