Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2024 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10451/65408 |
Resumo: | © The Author(s) 2024. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
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Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairmentCognitive impairmentParkinson’s diseaseParkinson’s disease dementiaSelf-rated health© The Author(s) 2024. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Purpose: To investigate the contributors to self-rated health in people with late-stage Parkinson's disease (PD) and cognitive impairment. Methods: A secondary analysis of baseline data from the international Care of Late-Stage Parkinsonism (CLaSP) cohort study was conducted. Participants with PD and either dementia or mild cognitive impairment or MMSE < 24/30 in the absence of major depression were included if they had completed the EQ-5D-3L assessment (n = 277). Factors associated with self-rated health (EQ-5D-3L Index and Visual Analogue Scale) were investigated through multivariable linear regression. Results: More severe PD (motor and non-motor) was associated with worse self-rated health. The EQ-5D-3L dimensions of Mobility, Self-Care and Usual Activities were almost universally affected; the latter two particularly severely. Being unable to perform usual activities or having moderate to extreme anxiety or depression were significantly associated with EQ-5D-3L Visual Analogue Scale, suggesting these are particularly valued. Worse motor impairment and function and the non-motor symptom domains of mood, perception, sexual function, and miscellaneous (e.g., pain) were associated with worse self-rated health, whereas greater burden of gastrointestinal symptoms was associated with better self-rated health in multivariate analysis. Better self-rated health was associated with recent PD nurse consultation, and higher doses of dopaminergic medication. Conclusion: Improvement of activities of daily living, mood and anxiety should be prioritised in clinical practice, with consideration of perception and sexual function in this population. Recent nurse consultations and higher antiparkinsonian doses are associated with better self-rated health, suggesting there is no room for a therapeutic nihilism in this population of people within a complex phase of PD.This report is independent research funded by the Rosetrees Trust and the Royal College of Physicians [RCP-2020\11]. The CLaSP study was funded by the European Commission (Joint Programme – Neurodegenerative Disease Research “European research projects for the evaluation of health care policies, strategies and interventions for Neurodegenerative Diseases”) through national funding bodies in all six countries [Economic and Social Research Council ES/L009250/1; BMBF, Marburg, Germany 01ED1403A, Munich, Germany 01ED1403B, Bordeaux, France: ANR-13-JPHC-0001–07, Lisbon, Portugal: HC/0002/ 2012, Lund, Sweden: HC-559–002, Nijmegen, Holland, 733051003].Springer NatureRepositório da Universidade de LisboaPigott, Jennifer S.Armstrong, MeganDavies, NathanDavis, DanielBloem, Bastiaan R.Lorenzl, StefanMeissner, Wassilios G.Odin, PerFerreira, Joaquim JDodel, RichardSchrag, Anette2024-07-23T11:21:26Z20242024-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/65408engQual Life Res. 2024 Jun 180962-934310.1007/s11136-024-03703-21573-2649info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-11-20T18:30:46Zoai:repositorio.ul.pt:10451/65408Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-11-20T18:30:46Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment |
| title |
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment |
| spellingShingle |
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment Pigott, Jennifer S. Cognitive impairment Parkinson’s disease Parkinson’s disease dementia Self-rated health |
| title_short |
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment |
| title_full |
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment |
| title_fullStr |
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment |
| title_full_unstemmed |
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment |
| title_sort |
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment |
| author |
Pigott, Jennifer S. |
| author_facet |
Pigott, Jennifer S. Armstrong, Megan Davies, Nathan Davis, Daniel Bloem, Bastiaan R. Lorenzl, Stefan Meissner, Wassilios G. Odin, Per Ferreira, Joaquim J Dodel, Richard Schrag, Anette |
| author_role |
author |
| author2 |
Armstrong, Megan Davies, Nathan Davis, Daniel Bloem, Bastiaan R. Lorenzl, Stefan Meissner, Wassilios G. Odin, Per Ferreira, Joaquim J Dodel, Richard Schrag, Anette |
| author2_role |
author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Pigott, Jennifer S. Armstrong, Megan Davies, Nathan Davis, Daniel Bloem, Bastiaan R. Lorenzl, Stefan Meissner, Wassilios G. Odin, Per Ferreira, Joaquim J Dodel, Richard Schrag, Anette |
| dc.subject.por.fl_str_mv |
Cognitive impairment Parkinson’s disease Parkinson’s disease dementia Self-rated health |
| topic |
Cognitive impairment Parkinson’s disease Parkinson’s disease dementia Self-rated health |
| description |
© The Author(s) 2024. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
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2024 |
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2024-07-23T11:21:26Z 2024 2024-01-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10451/65408 |
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http://hdl.handle.net/10451/65408 |
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eng |
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eng |
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Qual Life Res. 2024 Jun 18 0962-9343 10.1007/s11136-024-03703-2 1573-2649 |
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openAccess |
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application/pdf |
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Springer Nature |
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Springer Nature |
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