Anything but Conventional Chromatography Approaches in Bioseparation
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/141850 |
Resumo: | PTDC/BII-BIO/28878/2017 UIDB/04378/2020 UID/BIO/04565/2020 POCI-01-0145-FEDER-007728 LISBOA-01-0145-FEDER-028878 Future Fellowship (EP/N015916/1) Sem PDF conforme despacho. |
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7160 |
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Anything but Conventional Chromatography Approaches in Bioseparationaqueous-two phase systemscontinuous and integrated processescrystallizationhigh throughput process developmentmembrane technologynon-conventional chromatographyApplied Microbiology and BiotechnologyMolecular MedicinePTDC/BII-BIO/28878/2017 UIDB/04378/2020 UID/BIO/04565/2020 POCI-01-0145-FEDER-007728 LISBOA-01-0145-FEDER-028878 Future Fellowship (EP/N015916/1) Sem PDF conforme despacho.While packed bed chromatography, known as conventional chromatography, has been serving the biopharmaceutical industry for decades as the bioseparation method of choice, alternative approaches are likely to take an increasing leading role in the next few years. The high number of new biological drugs under development, and the need to make biopharmaceuticals widely accessible, has been driving the academia and industry in the quest of anything but conventional chromatography approaches. In this perspective paper, these alternative approaches are discussed in view of current and future challenges in the downstream processing field.DQ - Departamento de QuímicaUCIBIO - Applied Molecular Biosciences UnitRUNRoque, Ana Cecília AfonsoPina, Ana SofiaAzevedo, Ana MargaridaAires-Barros, RaquelJungbauer, AloisDi Profio, GianlucaHeng, Jerry Y. Y.Haigh, JonathanOttens, Marcel2022-07-13T22:19:50Z2020-08-012020-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/141850eng1860-6768PURE: 18349628https://doi.org/10.1002/biot.201900274info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:19:10Zoai:run.unl.pt:10362/141850Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:50:04.363651Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Anything but Conventional Chromatography Approaches in Bioseparation |
title |
Anything but Conventional Chromatography Approaches in Bioseparation |
spellingShingle |
Anything but Conventional Chromatography Approaches in Bioseparation Roque, Ana Cecília Afonso aqueous-two phase systems continuous and integrated processes crystallization high throughput process development membrane technology non-conventional chromatography Applied Microbiology and Biotechnology Molecular Medicine |
title_short |
Anything but Conventional Chromatography Approaches in Bioseparation |
title_full |
Anything but Conventional Chromatography Approaches in Bioseparation |
title_fullStr |
Anything but Conventional Chromatography Approaches in Bioseparation |
title_full_unstemmed |
Anything but Conventional Chromatography Approaches in Bioseparation |
title_sort |
Anything but Conventional Chromatography Approaches in Bioseparation |
author |
Roque, Ana Cecília Afonso |
author_facet |
Roque, Ana Cecília Afonso Pina, Ana Sofia Azevedo, Ana Margarida Aires-Barros, Raquel Jungbauer, Alois Di Profio, Gianluca Heng, Jerry Y. Y. Haigh, Jonathan Ottens, Marcel |
author_role |
author |
author2 |
Pina, Ana Sofia Azevedo, Ana Margarida Aires-Barros, Raquel Jungbauer, Alois Di Profio, Gianluca Heng, Jerry Y. Y. Haigh, Jonathan Ottens, Marcel |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
DQ - Departamento de Química UCIBIO - Applied Molecular Biosciences Unit RUN |
dc.contributor.author.fl_str_mv |
Roque, Ana Cecília Afonso Pina, Ana Sofia Azevedo, Ana Margarida Aires-Barros, Raquel Jungbauer, Alois Di Profio, Gianluca Heng, Jerry Y. Y. Haigh, Jonathan Ottens, Marcel |
dc.subject.por.fl_str_mv |
aqueous-two phase systems continuous and integrated processes crystallization high throughput process development membrane technology non-conventional chromatography Applied Microbiology and Biotechnology Molecular Medicine |
topic |
aqueous-two phase systems continuous and integrated processes crystallization high throughput process development membrane technology non-conventional chromatography Applied Microbiology and Biotechnology Molecular Medicine |
description |
PTDC/BII-BIO/28878/2017 UIDB/04378/2020 UID/BIO/04565/2020 POCI-01-0145-FEDER-007728 LISBOA-01-0145-FEDER-028878 Future Fellowship (EP/N015916/1) Sem PDF conforme despacho. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-08-01 2020-08-01T00:00:00Z 2022-07-13T22:19:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/141850 |
url |
http://hdl.handle.net/10362/141850 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1860-6768 PURE: 18349628 https://doi.org/10.1002/biot.201900274 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799138098039226368 |