An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples

Detalhes bibliográficos
Autor(a) principal: MalariaGEN
Data de Publicação: 2022
Outros Autores: Urbano Ferreira, Marcelo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/143839
Resumo: Publisher Copyright: © 2022 MalariaGEN et al.
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spelling An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samplesData resourceGenomic epidemiologyGenomicsMalariaPlasmodium vivaxMedicine (miscellaneous)Biochemistry, Genetics and Molecular Biology(all)SDG 3 - Good Health and Well-beingPublisher Copyright: © 2022 MalariaGEN et al.This report describes the MalariaGEN Pv4 dataset, a new release of curated genome variation data on 1,895 samples of Plasmodium vivax collected at 88 worldwide locations between 2001 and 2017. It includes 1,370 new samples contributed by MalariaGEN and VivaxGEN partner studies in addition to previously published samples from these and other sources. We provide genotype calls at over 4.5 million variable positions including over 3 million single nucleotide polymorphisms (SNPs), as well as short indels and tandem duplications. This enlarged dataset highlights major compartments of parasite population structure, with clear differentiation between Africa, Latin America, Oceania, Western Asia and different parts of Southeast Asia. Each sample has been classified for drug resistance to sulfadoxine, pyrimethamine and mefloquine based on known markers at the dhfr, dhps and mdr1 loci. The prevalence of all of these resistance markers was much higher in Southeast Asia and Oceania than elsewhere. This open resource of analysis-ready genome variation data from the MalariaGEN and VivaxGEN networks is driven by our collective goal to advance research into the complex biology of P. vivax and to accelerate genomic surveillance for malaria control and elimination.Individual Health Care (IHC)Instituto de Higiene e Medicina Tropical (IHMT)Global Health and Tropical Medicine (GHTM)RUNMalariaGENUrbano Ferreira, Marcelo2022-09-19T22:23:45Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/143839engPURE: 46500083https://doi.org/10.12688/wellcomeopenres.17795.1info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:22:36Zoai:run.unl.pt:10362/143839Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:51:09.883657Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
title An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
spellingShingle An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
MalariaGEN
Data resource
Genomic epidemiology
Genomics
Malaria
Plasmodium vivax
Medicine (miscellaneous)
Biochemistry, Genetics and Molecular Biology(all)
SDG 3 - Good Health and Well-being
title_short An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
title_full An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
title_fullStr An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
title_full_unstemmed An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
title_sort An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
author MalariaGEN
author_facet MalariaGEN
Urbano Ferreira, Marcelo
author_role author
author2 Urbano Ferreira, Marcelo
author2_role author
dc.contributor.none.fl_str_mv Individual Health Care (IHC)
Instituto de Higiene e Medicina Tropical (IHMT)
Global Health and Tropical Medicine (GHTM)
RUN
dc.contributor.author.fl_str_mv MalariaGEN
Urbano Ferreira, Marcelo
dc.subject.por.fl_str_mv Data resource
Genomic epidemiology
Genomics
Malaria
Plasmodium vivax
Medicine (miscellaneous)
Biochemistry, Genetics and Molecular Biology(all)
SDG 3 - Good Health and Well-being
topic Data resource
Genomic epidemiology
Genomics
Malaria
Plasmodium vivax
Medicine (miscellaneous)
Biochemistry, Genetics and Molecular Biology(all)
SDG 3 - Good Health and Well-being
description Publisher Copyright: © 2022 MalariaGEN et al.
publishDate 2022
dc.date.none.fl_str_mv 2022-09-19T22:23:45Z
2022
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/143839
url http://hdl.handle.net/10362/143839
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv PURE: 46500083
https://doi.org/10.12688/wellcomeopenres.17795.1
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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