Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2019 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.18/6596 |
Resumo: | Free PMC article |
| id |
RCAP_d2aef4646ebb1f4ca29a0adbd19d3d3a |
|---|---|
| oai_identifier_str |
oai:repositorio.insa.pt:10400.18/6596 |
| network_acronym_str |
RCAP |
| network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| repository_id_str |
7160 |
| spelling |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic AnalysisAmyloidosisApolipoproteinCardiomyopathyHeart FailureImagingNuclear MedicineDoenças GenéticasFree PMC articleAmyloidosis is a group of disorders characterised by the accumulation of extracellular deposits of insoluble protein aggregates. Clinical management depends on the accurate identification of the amyloid precursor and underlying cause. We describe a rare case of apolipoprotein A-IV cardiac amyloidosis, the diagnosis of which required mass spectrometry-based proteomic analysis.Learning points: To be able to perform the differential diagnosis of cardiac amyloidosis subtypes using imaging methods, analytical results and tissue analysis.To recognise the added value of mass spectrometry (MS)-based proteomic analysisThe Authors acknowledge Rede Nacional de Espectrometria de Massa, ROTEIRO/0028/2013, ref. LISBOA-01-0145-FEDER-022125, supported by COMPETE and North Portugal Regional Operational Programme (Norte2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). This work is partially funded by FCT - Fundação para a Ciência e a Tecnologia [UID/BIM/04293/2013].European Federation of Internal MedicineRepositório Científico do Instituto Nacional de SaúdeMartins, ElisabeteUrbano, JoanaLeite, SérgioPinto, AdrianaGarcia, RaquelBergantim, RuiRodrigues-Pereira, PedroCosta, Paulo PinhoOsório, HugoTavares, Isabel2020-05-05T22:30:08Z2019-11-272019-11-27T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/6596engEur J Case Rep Intern Med. 2019 Nov 27;6(12):001237. doi: 10.12890/2019_0012372284-259410.12890/2019_001237info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:41:45Zoai:repositorio.insa.pt:10400.18/6596Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:41:40.478931Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis |
| title |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis |
| spellingShingle |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis Martins, Elisabete Amyloidosis Apolipoprotein Cardiomyopathy Heart Failure Imaging Nuclear Medicine Doenças Genéticas |
| title_short |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis |
| title_full |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis |
| title_fullStr |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis |
| title_full_unstemmed |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis |
| title_sort |
Cardiac Amyloidosis Associated with Apolipoprotein A-IV Deposition Diagnosed by Mass Spectrometry-Based Proteomic Analysis |
| author |
Martins, Elisabete |
| author_facet |
Martins, Elisabete Urbano, Joana Leite, Sérgio Pinto, Adriana Garcia, Raquel Bergantim, Rui Rodrigues-Pereira, Pedro Costa, Paulo Pinho Osório, Hugo Tavares, Isabel |
| author_role |
author |
| author2 |
Urbano, Joana Leite, Sérgio Pinto, Adriana Garcia, Raquel Bergantim, Rui Rodrigues-Pereira, Pedro Costa, Paulo Pinho Osório, Hugo Tavares, Isabel |
| author2_role |
author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
| dc.contributor.author.fl_str_mv |
Martins, Elisabete Urbano, Joana Leite, Sérgio Pinto, Adriana Garcia, Raquel Bergantim, Rui Rodrigues-Pereira, Pedro Costa, Paulo Pinho Osório, Hugo Tavares, Isabel |
| dc.subject.por.fl_str_mv |
Amyloidosis Apolipoprotein Cardiomyopathy Heart Failure Imaging Nuclear Medicine Doenças Genéticas |
| topic |
Amyloidosis Apolipoprotein Cardiomyopathy Heart Failure Imaging Nuclear Medicine Doenças Genéticas |
| description |
Free PMC article |
| publishDate |
2019 |
| dc.date.none.fl_str_mv |
2019-11-27 2019-11-27T00:00:00Z 2020-05-05T22:30:08Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/6596 |
| url |
http://hdl.handle.net/10400.18/6596 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Eur J Case Rep Intern Med. 2019 Nov 27;6(12):001237. doi: 10.12890/2019_001237 2284-2594 10.12890/2019_001237 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
European Federation of Internal Medicine |
| publisher.none.fl_str_mv |
European Federation of Internal Medicine |
| dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
| instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
| instacron_str |
RCAAP |
| institution |
RCAAP |
| reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
| repository.mail.fl_str_mv |
|
| _version_ |
1799132161647837184 |