Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties

Detalhes bibliográficos
Autor(a) principal: Couto, Joana
Data de Publicação: 2020
Outros Autores: Figueirinha, Artur, Batista, Maria Teresa, Paranhos, António, Nunes, Carla, Gonçalves, Lídia, Marto, Joana, Fitas, Manuel, Pinto, Pedro, Ribeiro, Helena Margarida, Pina, Maria Eugénia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/62012
Resumo: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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spelling Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant PropertiesFragaria vesca L.antioxidant propertieshydrogeltopical applicationcutaneous compatibility© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Fragaria vesca L. (F. vesca), popularly known as wild strawberry, is a plant from the Rosaceae family, found in temperate and subtropical areas of the northern hemisphere. F. vesca leaves have been shown to have antiseptic, emollient, and dermatological protection properties, due to the presence of bioactive compounds, such as flavonoids, phenolic acids, ellagitannins, and proanthocyanidins. In this study, a F. vesca extract was obtained by an optimized extraction process, and was characterized by HPLC, ROS scavenging activity, cytotoxicity assays in HaCaT cells, and tyrosinase inhibitory activity determination. The most active extract was then incorporated in a hydrogel with hydroxyethylcellulose at 2% (w/w), which was characterized at the physicochemical, stability, cytotoxicity, and ROS scavenging activity levels to evaluate its quality, safety, and efficacy. In vivo studies, human repeat insult patch testing, and an assay to determine their antioxidant efficacy, were also performed. The results showed that the Fragaria vesca extracts had antioxidant activity and that the F. vesca extract-based hydrogel exhibited cutaneous compatibility, acceptability and antioxidant efficacy, being stable, and suitable for topical application.This work was supported by UID/QUI/50006/2019 with funding from FCT/MCTES through national funds, and by Programa de Cooperación Interreg V-A España—Portugal (POCTEP) 2014–2020 (project 0377_IBERPHENOL_6_E). This research was also funded by Fundação para a Ciência e a Tecnologia, Portugal (UID/DTP/04138/2019 to iMedUlisboa) and by PhD Trials.MDPIRepositório da Universidade de LisboaCouto, JoanaFigueirinha, ArturBatista, Maria TeresaParanhos, AntónioNunes, CarlaGonçalves, LídiaMarto, JoanaFitas, ManuelPinto, PedroRibeiro, Helena MargaridaPina, Maria Eugénia2024-01-22T17:00:28Z2020-02-142023-02-27T18:31:05Z2020-02-14T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/62012engCouto J, Figueirinha A, Batista MT, Paranhos A, Nunes C, Gonçalves LM, et al. Fragaria vesca l. Extract: a promising cosmetic ingredient with antioxidant properties. Antioxidants [Internet]. 14 de fevereiro de 2020;9(2):154. Disponível em: https://www.mdpi.com/2076-3921/9/2/154cv-prod-117839810.3390/antiox90201542-s2.0-85079683806info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-29T01:19:37Zoai:repositorio.ul.pt:10451/62012Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:58:29.559278Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties
title Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties
spellingShingle Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties
Couto, Joana
Fragaria vesca L.
antioxidant properties
hydrogel
topical application
cutaneous compatibility
title_short Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties
title_full Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties
title_fullStr Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties
title_full_unstemmed Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties
title_sort Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties
author Couto, Joana
author_facet Couto, Joana
Figueirinha, Artur
Batista, Maria Teresa
Paranhos, António
Nunes, Carla
Gonçalves, Lídia
Marto, Joana
Fitas, Manuel
Pinto, Pedro
Ribeiro, Helena Margarida
Pina, Maria Eugénia
author_role author
author2 Figueirinha, Artur
Batista, Maria Teresa
Paranhos, António
Nunes, Carla
Gonçalves, Lídia
Marto, Joana
Fitas, Manuel
Pinto, Pedro
Ribeiro, Helena Margarida
Pina, Maria Eugénia
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Couto, Joana
Figueirinha, Artur
Batista, Maria Teresa
Paranhos, António
Nunes, Carla
Gonçalves, Lídia
Marto, Joana
Fitas, Manuel
Pinto, Pedro
Ribeiro, Helena Margarida
Pina, Maria Eugénia
dc.subject.por.fl_str_mv Fragaria vesca L.
antioxidant properties
hydrogel
topical application
cutaneous compatibility
topic Fragaria vesca L.
antioxidant properties
hydrogel
topical application
cutaneous compatibility
description © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
publishDate 2020
dc.date.none.fl_str_mv 2020-02-14
2020-02-14T00:00:00Z
2023-02-27T18:31:05Z
2024-01-22T17:00:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/62012
url http://hdl.handle.net/10451/62012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Couto J, Figueirinha A, Batista MT, Paranhos A, Nunes C, Gonçalves LM, et al. Fragaria vesca l. Extract: a promising cosmetic ingredient with antioxidant properties. Antioxidants [Internet]. 14 de fevereiro de 2020;9(2):154. Disponível em: https://www.mdpi.com/2076-3921/9/2/154
cv-prod-1178398
10.3390/antiox9020154
2-s2.0-85079683806
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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