Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10174/29887 https://doi.org/10.3390/jcm9051491 |
Resumo: | In this report, updated information and future perspectives about the use of saliva as a sample for laboratory analysis of the Covid-19 are highlighted. Saliva can be used for the direct detection of the SARS-CoV-2 virus, the quantification of the specific immunoglobulins produced against it, and for the evaluation of the non-specific, innate immune response of the patient. Moreover, a deeper knowledge of potential changes in the saliva proteome in this disease may allow the identification of new diagnostic and prognostic biomarkers, or even help our understanding of the mechanisms associated with the disease. With the development of appropriate sample collection and processing methods and the use of adequate assays, saliva can provide useful clinical information about the disease and could be potentially included in guidelines for sample collection for the diagnosis, disease management, and control of Covid-19. |
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Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General PerspectiveIn this report, updated information and future perspectives about the use of saliva as a sample for laboratory analysis of the Covid-19 are highlighted. Saliva can be used for the direct detection of the SARS-CoV-2 virus, the quantification of the specific immunoglobulins produced against it, and for the evaluation of the non-specific, innate immune response of the patient. Moreover, a deeper knowledge of potential changes in the saliva proteome in this disease may allow the identification of new diagnostic and prognostic biomarkers, or even help our understanding of the mechanisms associated with the disease. With the development of appropriate sample collection and processing methods and the use of adequate assays, saliva can provide useful clinical information about the disease and could be potentially included in guidelines for sample collection for the diagnosis, disease management, and control of Covid-19.Journal of Clinical Medicine2021-06-08T11:03:29Z2021-06-082020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10174/29887http://hdl.handle.net/10174/29887https://doi.org/10.3390/jcm9051491porCeron JJ, Lamy E, Martinez-Subiela S, Lopez-Jornet P, Capela-Silva F, Eckersall PD, Tvarijonaviciute A (2020) Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective. J Clin Med, 9, 1491. DOI: 10.3390/jcm9051491ndecsl@uevora.ptndndfcs@uevora.ptndnd362Ceron, JJLamy, EMartinez-Subiela, SLopez-Jornet, PCapela e Silva, FEckersall, DTvarijonaviciute, Ainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T19:26:11Zoai:dspace.uevora.pt:10174/29887Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:18:55.919824Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective |
title |
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective |
spellingShingle |
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective Ceron, JJ |
title_short |
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective |
title_full |
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective |
title_fullStr |
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective |
title_full_unstemmed |
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective |
title_sort |
Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective |
author |
Ceron, JJ |
author_facet |
Ceron, JJ Lamy, E Martinez-Subiela, S Lopez-Jornet, P Capela e Silva, F Eckersall, D Tvarijonaviciute, A |
author_role |
author |
author2 |
Lamy, E Martinez-Subiela, S Lopez-Jornet, P Capela e Silva, F Eckersall, D Tvarijonaviciute, A |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Ceron, JJ Lamy, E Martinez-Subiela, S Lopez-Jornet, P Capela e Silva, F Eckersall, D Tvarijonaviciute, A |
description |
In this report, updated information and future perspectives about the use of saliva as a sample for laboratory analysis of the Covid-19 are highlighted. Saliva can be used for the direct detection of the SARS-CoV-2 virus, the quantification of the specific immunoglobulins produced against it, and for the evaluation of the non-specific, innate immune response of the patient. Moreover, a deeper knowledge of potential changes in the saliva proteome in this disease may allow the identification of new diagnostic and prognostic biomarkers, or even help our understanding of the mechanisms associated with the disease. With the development of appropriate sample collection and processing methods and the use of adequate assays, saliva can provide useful clinical information about the disease and could be potentially included in guidelines for sample collection for the diagnosis, disease management, and control of Covid-19. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-01T00:00:00Z 2021-06-08T11:03:29Z 2021-06-08 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10174/29887 http://hdl.handle.net/10174/29887 https://doi.org/10.3390/jcm9051491 |
url |
http://hdl.handle.net/10174/29887 https://doi.org/10.3390/jcm9051491 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Ceron JJ, Lamy E, Martinez-Subiela S, Lopez-Jornet P, Capela-Silva F, Eckersall PD, Tvarijonaviciute A (2020) Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective. J Clin Med, 9, 1491. DOI: 10.3390/jcm9051491 nd ecsl@uevora.pt nd nd fcs@uevora.pt nd nd 362 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Journal of Clinical Medicine |
publisher.none.fl_str_mv |
Journal of Clinical Medicine |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799136671269126144 |